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Kost Forer Gabbay & Kasierer 144 Menachem Begin Road Tel-Aviv 6492102, Israel Tel: +972-3-6232525 Fax: +972-3-5622555 ey.com REPORT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM To the Shareholders and Board of Direct

Key Takeaway: OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM the Shareholders and Board of Directors of on the Financial Statements have audited the accompanying consolidated balance sheet of Can-Fite Ltd and its subsidiary (the "Company") as of December 31, 2019 and 2018, and the relate

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OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM
the Shareholders and Board of Directors of
on the Financial Statements
have audited the accompanying consolidated balance sheet of Can-Fite Ltd and its subsidiary (the "Company") as of
December 31, 2019 and 2018, and the related consolidated statements of comprehensive loss, shareholders' equity and cash
flows for each of the three years in the period ended December 31, 2019, and the related notes (collectively referred to as the
"consolidated financial statements"). In our opinion, the consolidation financial statements present fairly, in all
material respects, the financial position of the Company at December 31, 2019 and 2018, and the results of its operations and
its cash flows for each of the three years in the period ended December 31, 2019, in conformity with U.S. generally accepted accounting
financial statements are the responsibility of the Company's management. Our responsibility is to express an opinion on
the Company's financial statements based on our audits. We are a public accounting firm registered with the Public Company
Accounting Oversight Board (United States) (PCAOB) and are required to be independent with respect to the Company in accordance
with the U.S. federal securities laws and the applicable rules and regulations of the Securities and Exchange Commission and the
conducted our audits in accordance with the standards of the PCAOB. Those standards require that we plan and perform the audit
to obtain reasonable assurance about whether the financial statements are free of material misstatement, whether due to error
or fraud. The Company is not required to have, nor were we engaged to perform, an audit of its internal control over financial
reporting. As part of our audits we are required to obtain an understanding of internal control over financial reporting but not
for the purpose of expressing an opinion on the effectiveness of the Company's internal control over financial reporting.
Accordingly, we express no such opinion.
audits included performing procedures to assess the risks of material misstatement of the financial statements, whether due to
error or fraud, and performing procedures that respond to those risks. Such procedures included examining, on a test basis, evidence
regarding the amounts and disclosures in the financial statements. Our audits also included evaluating the accounting principles
used and significant estimates made by management, as well as evaluating the overall presentation of the financial statements.
We believe that our audits provide a reasonable basis for our opinion.
FORER GABBAY & KASIERER
have served as the Company's auditor since at least 2001, but we are unable to determine the specific year.
BIOPHARMA LTD. AND ITS SUBSIDIARY
dollars in thousands except for share and per share data)
December 31,
2019 2018
Note USD
ASSETS
CURRENT ASSETS:
Cash and cash equivalents $ 2,697 $ 3,615
Other accounts receivables and prepaid expenses 3 4,383 4,015
Short-term investment 4 64 273
Total current assets 7,144 7,903
NON-CURRENT ASSETS:
Lease deposit - 2
Other non-current receivables 5 912 -
Operating lease right of use assets 12 82 -
Property, plant and equipment, net 6 36 47
Total long-term assets 1,030 49
Total assets $ 8,174 $ 7,952
accompanying notes are an integral part of the consolidated financial statements.
BIOPHARMA LTD. AND ITS SUBSIDIARY
dollars in thousands except for share and per share data)
December 31,
2019 2018
Note USD
LIABILITIES AND SHAREHOLDERS' EQUITY
CURRENT LIABILITIES:
Trade payables $ 2,156 $ 1,071
Current maturity of operating lease liability 12 36 -
Deferred revenues 11 469 926
Other accounts payable 7 610 1,122
Total current liabilities 3,271 3,119
NON-CURRENT LIABILITIES:
Long - term operating lease liability 12 39 -
Deferred revenues 9 2,422 1,818
Total Long-term liabilities 2,461 1,818
CONTIGENT LIABILITIES AND COMMITMENTS 9
SHAREHOLDERS' EQUITY: 10
Ordinary shares of NIS 0.25 par value - Authorized: 500,000,000 shares at December 31, 2019 and 2018; Issued and outstanding: 120,652,683 shares as of December 31, 2019; 40,399,290 shares as of December 31, 2018 8,225 2,635
Additional paid-in capital 103,401 96,939
Accumulated other comprehensive income 1,127 1,127
Accumulated deficit (110,311 ) (97,686 )
Total shareholders' equity 2,442 3,015
Total liabilities and shareholders' equity $ 8,174 $ 7,952
accompanying notes are an integral part of the consolidated financial statements.
BIOPHARMA LTD. AND ITS SUBSIDIARY
STATEMENTS OF COMPREHENSIVE LOSS
dollars in thousands except for share and per share data)
Year ended December 31,
2019 2018 2017
Note USD
Revenues 9 $ 2,032 $ 3,820 $ 789
Research and development expenses (10,976 ) (6,075 ) (5,106 )
General and administrative expenses (3,063 ) (3,159 ) (2,868 )
Operating loss (12,007 ) (5,414 ) (7,185 )
Other income 1b - - 769
Total Financial income (expense), net 13 (618 ) (1,153 ) 1,603
Loss before taxes on income (12,625 ) (6,567 ) (4,813 )
Taxes on income 15 - (4 ) (29 )
Net loss $ (12,625 ) $ (6,571 ) $ (4,842 )
Basic and diluted net loss per share 14 $ (0.14 ) $ (0.17 ) $ (0.14 )
Other comprehensive loss:
Adjustment arising from translating financial statements from functional currency to presentation currency - - 636
Total comprehensive loss $ (12,625 ) $ (6,571 ) $ (4,206 )
Net loss Attributable to:
Equity holders of the Company $ (12,625 ) $ (6,571 ) $ (4,748 )
Non-controlling interests - - (94 )
(12,625 ) (6,571 ) (4,842 )
Total comprehensive loss attributable to:
Equity holders of the Company (12,625 ) (6,571 ) (4,112 )
Non-controlling interests - - (94 )
$ (12,625 ) $ (6,571 ) $ (4,206 )
Weighted average number of ordinary shares used in computing basic and diluted net loss per share 85,909,859 38,902,214 32,525,138
accompanying notes are an integral part of the consolidated financial statements.
BIOPHARMA LTD. AND ITS SUBSIDIARY
STATEMENTS OF CHANGES IN EQUITY
dollars in thousands except for share and per share data)
Can-Fite Biopharma Ltd. Shareholders' Equity
Ordinary shares Additional paid-in Treasury Accumulated other comprehensive Accumulated Non- controlling Total
Number Amount capital Shared Income deficit Total interests Equity
Balance as of January 1, 2017 28,156,728 $ 1,783 $ 88,578 $ (970 ) $ 491 $ (86,017 ) $ 3,865 $ 42 $ 3,907
Net loss - - - - - (4,748 ) (4,748 ) (94 ) (4,842 )
Adjustment arising from translating financial statements from functional currency to presentation currency - - - - 636 - 636 - 636
Total comprehensive loss - - - - 636 (4,748 ) (4,112 ) (94 ) (4,206 )
Issuance of share capital and warrants, net of issuance expenses of $ 621 5,000,000 330 2,482 - - - 2,812 - 2,812
Issuance of share capital 138,890 10 85 - - - 95 - 95
Proceeds from sale of subsidiary in previously consolidated subsidiaries - - (838 ) 970 - - 132 52 184
Share-based payments - - 192 - - - 192 - 192
Balance as of December 31, 2017 33,295,618 $ 2,123 $ 90,499 - $ 1,127 $ (90,765 ) $ 2,984 - $ 2,984
accompanying notes are an integral part of the consolidated financial statements.
BIOPHARMA LTD. AND ITS SUBSIDIARY
STATEMENTS OF CHANGES IN EQUITY
dollars in thousands except for share and per share data)
Ordinary shares Additional paid- Accumulated other comprehensive Accumulated Total shareholders'
Number Amount in capital Income deficit equity
Balance as of January 1, 2018 33,295,618 $ 2,123 $ 90,499 $ 1,127 $ (90,765 ) $ 2,984
Liability reclassified to equity (*) - - 2,030 - - 2,030
Cumulative effect of initial adoption of ASC 606 as of January 1, 2018 - - - - (350 ) (350 )
Issuance of share capital and warrants, net of issuance expenses of $ 613 6,667,672 482 3,905 - - 4,387
Issuance of share capital 437,000 30 252 - - 282
Share-based payments - - 253 - - 253
Net loss - - 0 - (6,571 ) $ (6,571 )
Balance as of December 31, 2018 40,399,290 $ 2,635 $ 96,939 $ 1,127 $ (97,686 ) $ 3,015
Issuance of share capital and warrants, net of issue expenses of $ 1,382 79,256,703 5,518 6,149 - - 11,667
Issuance of share capital 996,690 72 43 - - 115
Share-based payments - - 270 - - 270
Net loss - - - - (12,625 ) (12,625 )
Balance as of December 31, 2019 120,652,683 $ 8,225 $ 103,401 $ 1,127 $ (110,311 ) $ 2,442
accompanying notes are an integral part of the consolidated financial statements.
BIOPHARMA LTD. AND ITS SUBSIDIARY
STATEMENTS OF CASH FLOWS
dollars in thousands except for share and per share data)
Year ended December 31,
2019 2018 2017
USD
Cash flows from operating activities:
Net loss $ (12,625 ) $ (6,571 ) $ (4,842 )
Adjustments required to reconcile net loss to net cash used in operating activities:
Depreciation of property, plant and equipment and amortization 14 14 19
Decrease in operating lease right of use asset 28 - -
Change in other receivables 201 - -
Share-based payment 385 535 192
Changes in fair value of warrants liability exercisable into shares - - (1,965 )
Changes in fair value of short-term investment 209 644 5
Gain from sale of investment in previously consolidated subsidiary - - (769 )
Issuance costs - - 302
Decrease in operating lease liability (33 ) - -
Exchange differences on balances of cash and cash equivalents (2 ) 89 83
Increase in accounts receivable, prepaid expenses 270 (853 ) (2,907 )
Increase in trade payable 1,085 644 293
Increase (decrease) in deferred revenues 146 1,218 (289 )
Increase (decrease) in other accounts payable (512 ) 125 906
Net cash used in operating activities $ (10,834 ) $ (4,155 ) $ (8,972 )
Cash flows from investing activities:
Purchase of property, plant and equipment (3 ) (33 ) (7 )
Increase in other receivables (250 ) - -
Proceeds from sale of investments in previously consolidated subsidiary - - (22 )
Net cash used in investing activities (253 ) (33 ) (29 )
Cash flows from financing activities:
Issuance of share capital and warrants, net of issuance expenses 10,167 4,387 4,474
Net cash provided by financing activities 10,167 4,387 4,474
Exchange differences on balances of cash and cash equivalents 2 (89 ) (83 )
Increase (decrease) in cash and cash equivalents (918 ) 110 (4,610 )
Cash and cash equivalents at the beginning of the year 3,615 3,505 8,115
Cash and cash equivalents at the end of the year 2,697 3,615 3,505
Supplemental disclosure of cash flow information:
Cash paid during the year for income taxes - 4 29
Cash paid during the year for interest 29 18 23
accompanying notes are an integral part of the consolidated financial statements.
BIOPHARMA LTD. AND ITS SUBSIDIARY
TO CONSOLIDATED FINANCIAL STATEMENTS
dollars in thousands except for share and per share data)
Biopharma Ltd. (the "Company") was incorporated and started to operate in September 1994 as a private Israeli company.
Can-Fite is a clinical-stage biopharmaceutical company focused on developing orally bioavailable small molecule therapeutic products
for the treatment of autoimmune-inflammatory, oncological and sexual dysfunction indications. Its platform technology utilizes
the Gi protein associated A3AR as a therapeutic target. A3AR is highly expressed in inflammatory and cancer cells, and not significantly
expressed in normal cells, suggesting that the receptor could be a unique target for pharmacological intervention. The Company's
pipeline of drug candidates are synthetic, highly specific agonists and allosteric modulators, or ligands or molecules that initiate
molecular events when binding with target proteins, targeting the A3AR.
The Company's ordinary
shares have been publicly traded on the Tel-Aviv Stock Exchange since October 2005 under the symbol "CFBI" and the
Company's American Depositary Shares ("ADSs") began public trading on the over the counter market in the U.S.
in October 2012 and since November 2013 the Company's ADSs have been publicly traded on the NYSE American under the symbol
"CANF". Each ADS represents 30 ordinary shares of the Company.
May 21, 2017, OphthaliX and a wholly-owned private Israeli subsidiary of OphthaliX, Bufiduck Ltd. (the "Merger Sub"),
and Wize Pharma Ltd. ("Wize"), an Israeli company formerly listed on the Tel Aviv Stock Exchange currently focused
on the treatment of ophthalmic disorders, including dry eye syndrome, entered into an Agreement and Plan of Merger (the "Merger
Agreement"), providing for the merger of the Merger Sub with and into Wize, with Wize becoming a wholly-owned subsidiary
of OphthaliX and the surviving corporation of the merger (the "Merger"). On November 16, 2017, the Merger was completed.
As a result of the Merger, the Company's ownership of OphthaliX, immediately post-Merger, became approximately 8% of the
outstanding shares of common stock. In addition, immediately prior to the Merger, OphthaliX sold on an "as is" basis
to the Company all the ordinary shares of Eyefite in exchange for the irrevocable cancellation and waiver of all indebtedness
owed by OphthaliX and Eyefite to the Company, including approximately USD 5,000 of deferred payments owed by OphthaliX and Eyefite
to the Company and, as part of the purchase of Eyefite, the Company also assumed certain accrued milestone payments in the amount
of USD 175 under a license agreement previously entered into with the NIH. In addition, that certain exclusive license of Piclidenoson
granted to OphthaliX by the Company and a related services agreement was terminated. In connection with the Merger, OphthaliX
was renamed Wize Pharma, Inc. As a result of the Merger, the Company recorded a capital gain of USD 769.
of December 31, 2019, Eyefite had no activity.
the Company intends to continue to finance its operating activities by raising capital and seeking collaborations with multinational
companies in the industry. There are no assurances that the Company will be successful in obtaining an adequate level of financing
needed for its long-term research and development activities.
the Company will not have sufficient liquidity resources, the Company may not be able to continue the development of all of its
products or may be required to implement a cost reduction and may be required to delay part of its development programs. The Company's
management and board of directors are of the opinion that its current financial resources will be sufficient to continue the development
of the Company's products for at least the next twelve months.
BIOPHARMA LTD. AND ITS SUBSIDIARY
TO CONSOLIDATED FINANCIAL STATEMENTS
dollars in thousands except for share and per share data)
the principal adjustments made in representing its IFRS financial statements, in order to comply with U.S. GAAP, is provided below.
Under IFRS, the Company recognized depreciation expense of operating
lease right of use assets and interest expense on lease liabilities. Under U.S. GAAP, the Company recognized a single lease cost,
calculated so that the remaining cost of the lease is allocated over the remaining lease term on a straight-line basis. As a result,
as of December 31, 2019, operating lease right of use assets has decreased by $1, finance expenses decreased by $3 and general
and administrative expense increased by $4 for the year ended December 31, 2019.
Under IFRS, the Company has
Last updated: Jun 1, 2020