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NOTE PURCHASE AGREEMENT
THIS NOTE PURCHASE AGREEMENT (this
Agreement ) is made as of February 10, 2023 (the Effective Date ), by and between CALCIMEDICA, INC., a Delaware corporation (the
Company ), and GRAYBUG VISION, INC., a Delaware corporation ( Purchaser ). Capitalized terms used herein and not otherwise defined have the meanings ascribed to
them in that certain Agreement and Plan of Merger and Reorganization, dated as of November 21, 2022, as amended February 10, 2023 (the Merger Agreement ), by and among the Company, Purchaser and Camaro Merger Sub, Inc., a
Delaware corporation and wholly-owned subsidiary of Purchaser.
To provide the Company with additional resources to conduct its business and to consummate the Merger, Purchaser is willing to provide a
bridge loan to the Company in an aggregate principal amount of up to $2,000,000.00 subject to the terms and conditions specified herein.
NOW, THEREFORE, in consideration of the foregoing, and the representations, warranties,
covenants and conditions set forth below, the Company and Purchaser, intending to be legally bound, hereby agree as follows:
AMOUNT AND TERMS OF THE LOAN. Subject to the terms and conditions of this Agreement, Purchaser agrees to lend to the Company at the Closings (as
hereinafter defined) an aggregate principal amount of up to $2,000,000.00 (the Loan Amount and the Loan ), against the issuance and delivery by the Company of promissory notes for up to the Loan Amount, in
substantially the form attached hereto as EXHIBIT A (the Note ).
2.1 Initial Closing. The initial sale and purchase of a Note, which shall be for a principal amount of $500,000.00 (the Initial
Closing ) shall be held at the Company s offices on the third Business Day following the Effective Date or at such other place and time as the Company and Purchaser may mutually agree.
2.2 Additional Closings. Subject to the terms and conditions of this Agreement, the Company may issue and deliver, and the Purchaser may
purchase from the Company, additional Notes, each for a principal amount of $500,000.00, at one or more additional closings (the Additional Closings and collectively with the Initial Closing, the Closings , and
each a Closing ) following the Initial Closing through the Closing Date (as defined in the Merger Agreement).
2.3 Delivery. At the Closings (i) Purchaser shall deliver to the Company a check or wire transfer funds in the principal amount of
the applicable Note; and (ii) the Company shall issue and deliver to Purchaser a Note in favor of Purchaser payable in the principal amount of such Note.
The Company hereby represents and warrants to Purchaser
and agrees with Purchaser as follows:
3.1 Organization. The Company is a corporation duly organized, validly existing and in good
standing under the laws of the State of Delaware.
3.2 Corporate Power. The Company will have at the Closing all requisite
corporate power to execute and deliver this Agreement and to issue the applicable Note (collectively, the Loan Documents ) and to carry out and perform its obligations under the terms of this Agreement and under the terms of the
applicable Note. The Company s Board of Directors has approved the Loan Documents.
3.3 Authorization. All corporate action on
the part of the Company, its directors and its stockholders necessary for the authorization, execution, delivery and performance of this Agreement by the Company and the performance of the Company s obligations hereunder has been taken. This
Agreement and the Notes, when executed and delivered by the Company, shall constitute valid and binding obligations of the Company enforceable in accordance with their terms, subject to laws of general application relating to bankruptcy, insolvency,
the relief of debtors and, with respect to rights to indemnity, subject to federal and state securities laws.
Consents. All material consents, approvals, orders, or authorizations of, or registrations, qualifications, designations, declarations, or filings with, any governmental authority, required on the part of the Company in connection with the valid
execution and delivery of this Agreement, the offer, sale or issuance of the applicable Note or the consummation of any other transaction hereunder shall have been obtained and will be effective at the Closing.
3.5 Offering. Assuming the accuracy of the representations and warranties of Purchaser contained in Section 4 hereof, the offer,
issue, and sale of the applicable Note is and will be exempt from the registration and prospectus delivery requirements of the Securities Act of 1933, as amended (the Act ), and have been registered or qualified (or are exempt from
registration and qualification) under the registration, permit, or qualification requirements of all applicable state securities laws.
3.6 Use of Proceeds. The Company shall use the proceeds of the Loan solely for the payment of payroll, rent, preclinical and clinical
trial expenses, regulatory consulting fees and other similar operating expenses in the ordinary course of business, and for the payment of the fees of Ernst & Young LLP in connection with the Merger, or other expenses if pre-approved by the Chief Executive Officer or Chief Financial Officer of Purchaser.
Indebtedness. The Company shall not repay or prepay any of the Company s indebtedness for borrowed money (including the indebtedness evidenced by the promissory notes the Company issued in connection with the signing of the Merger
Agreement) other than the Notes (collectively, the Other Indebtedness ) for so long as any principal or interest under the Notes remains outstanding.
4.1 Organization. Purchaser is a corporation duly organized, validly existing and in
good standing under the laws of the State of Delaware.
4.2 Corporate Power. Purchaser will have at the Closing all requisite
corporate power to execute and deliver each Loan Document to which it is party and to carry out and perform its obligations under the terms of such Loan Documents. The Board of Directors of Purchaser has approved the Loan Documents.
4.3 Authorization. All corporate action on the part of Purchaser, its directors and its stockholders necessary for the authorization,
execution, delivery and performance of this Agreement by Purchaser and the performance of Purchaser s obligations hereunder has been taken. This Agreement, when executed and delivered by Purchaser, shall constitute a valid and binding
obligation of Purchaser enforceable in accordance with their terms, subject to laws of general application relating to bankruptcy, insolvency, the relief of debtors and, with respect to rights to indemnity, subject to federal and state securities
4.4 Purchase for Own Account. Purchaser represents that it is acquiring the applicable Note solely for its own account and
beneficial interest for investment and not for sale or with a view to distribution of the applicable Note or any part thereof, has no present intention of selling (in connection with a distribution or otherwise), granting any participation in, or
otherwise distributing the same, and does not presently have reason to anticipate a change in such intention.
Sophistication. Without lessening or obviating the representations and warranties of the Company set forth in Section 3, Purchaser hereby: (i) acknowledges that it has received all the information it has requested from the Company and
it considers necessary or appropriate for deciding whether to acquire the applicable Note, (ii) represents that it has had an opportunity to ask questions and receive answers from the Company regarding the terms and conditions of the offering
of the applicable Note and to obtain any additional information necessary to verify the accuracy of the information given Purchaser and (iii) further represents that it has such knowledge and experience in financial and business matters that it
is capable of evaluating the merits and risk of this investment.
4.6 Ability to Bear Economic Risk. Purchaser acknowledges that
investment in the applicable Note involves a high degree of risk, and represents that it is able, without materially impairing its financial condition, to hold the applicable Note for an indefinite period of time and to suffer a complete loss of its
4.7 Accredited Investor Status. Purchaser is an accredited investor as such term is defined in Rule 501
The obligations of Purchaser under Section 2 of this Agreement are subject to the
fulfillment or Purchaser s waiver, on or before each Closing (except as set forth below), of each of the following conditions:
Representations and Warranties. Each of the representations and warranties of the Company contained in Section 3 shall be true and complete.
5.2 Covenants. The Company shall have performed and complied with all agreements, obligations and conditions contained in this Agreement
that are required to be performed or complied with by it.
5.3 Use of Proceeds. The Company shall be compliance with
Section 3.6 of this Agreement with respect to use of proceeds of the Loan.
5.4 Approvals. Solely with respect to an Additional
Closing, the Chief Executive Officer or the Chief Financial Officer of Purchaser shall have approved Purchaser s purchase of the Note, which approval shall be at Purchaser s good faith discretion.
6.1 Binding Agreement. The terms and conditions of this Agreement shall inure to the benefit of and be binding upon the
respective successors and assigns of the parties. Nothing in this Agreement, expressed or implied, is intended to confer upon any third party any rights, remedies, obligations, or liabilities under or by reason of this Agreement, except as expressly
provided in this Agreement.
6.2 Governing Law. This Agreement shall be governed by, and construed in accordance with, the laws of
the State of Delaware, regardless of the laws that might otherwise govern under applicable principles of conflicts of laws. In any action or suit between the Company and Purchaser arising out of or relating to this Agreement: (a) each of the
Company and Purchaser irrevocably and unconditionally consents and submits to the exclusive jurisdiction and venue of the state and federal courts located in the State of Delaware; (b) if any such action or suit is commenced in a state court,
then, subject to applicable Legal Requirements, neither the Company nor Purchaser shall object to the removal of such action or suit to any federal court located in the District of Delaware; and (c) each of the Company and Purchaser irrevocably
waives the right to trial by jury.
6.3 Counterparts. This Agreement may be executed in two or more counterparts, each of which
shall be deemed an original, but all of which together shall constitute one and the same instrument.
6.4 Titles and Subtitles. The
titles and subtitles used in this Agreement are used for convenience only and are not to be considered in construing or interpreting this Agreement.
6.5 Notices. All notices required or permitted hereunder shall be made in accordance with Section 10.8 of the Merger Agreement.
6.6 Modification; Waiver. No modification or waiver of any provision of this
Agreement or consent to departure therefrom shall be effective unless in writing and approved by the Company and Purchaser. Any provision of the Notes may be amended or waived by the written consent of the Company and Purchaser.
6.7 Expenses. The Company and Purchaser shall each bear its respective expenses and legal fees incurred with respect to this Agreement
and the transactions contemplated herein.
6.8 Delays or Omissions. It is agreed that no delay or omission to exercise any right,
power or remedy accruing to Purchaser, upon any breach or default of the Company under this Agreement or the Notes shall impair any such right, power or remedy, nor shall it be construed to be a waiver of any such breach or default, or any
acquiescence therein, or of or in any similar breach or default thereafter occurring; nor shall any waiver of any single breach or default be deemed a waiver of any other breach or default theretofore or thereafter occurring. It is further agreed
that any waiver, permit, consent or approval of any kind or character by Purchaser of any breach or default under this Agreement, or any waiver by Purchaser of any provisions or conditions of this Agreement must be in writing and shall be effective
only to the extent specifically set forth in writing and that all remedies, either under this Agreement, or by law or otherwise afforded to Purchaser, shall be cumulative and not alternative.
6.9 Entire Agreement. This Agreement and the Notes constitute the full and entire understanding and agreement between the parties with
regard to the subjects hereof, and no party shall be liable or bound to any other party in any manner by any representations, warranties, covenants and agreements except as specifically set forth herein.
6.10 Termination. This Agreement shall terminate and be of no further force or effect at such time as the Notes issued under this
Agreement have been canceled or terminated in accordance with the terms of the Notes.
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IN WITNESS WHEREOF, the parties have
executed this NOTE PURCHASE AGREEMENT as of the date first written above.
[Signature Page to Note Purchase Agreement]
FORM OF PROMISSORY NOTE
THIS PROMISSORY NOTE HAS NOT BEEN REGISTERED UNDER THE SECURITIES ACT OF 1933, AS AMENDED. NO SALE OR
DISPOSITION MAY BE EFFECTED EXCEPT IN COMPLIANCE WITH RULE 144 UNDER SAID ACT OR AN EFFECTIVE REGISTRATION STATEMENT RELATED THERETO OR AN OPINION OF COUNSEL FOR THE HOLDER SATISFACTORY TO PAYOR THAT SUCH REGISTRATION IS NOT REQUIRED UNDER THE ACT
OR RECEIPT OF A NO-ACTION LETTER FROM THE SECURITIES AND EXCHANGE COMMISSION.