CalciMedica Announces Pricing of Public Offering of Common Stock

CalciMedica Announces Pricing of Public Offering of Common Stock

LA JOLLA, Calif., October 30, 2024 /PRNewswire/ CalciMedica, Inc. ( CalciMedica or the Company ) (Nasdaq: CALC), a

clinical-stage biopharmaceutical company focused on developing novel calcium release-activated calcium ( CRAC ) channel inhibition therapies for acute and chronic inflammatory and immunologic illnesses, today announced the pricing of an

underwritten public offering of 2,720,000 shares of its common stock at a price to the public of $3.75 per share. The gross proceeds to the Company from the offering, before deducting underwriting discounts and commissions and offering expenses, are

expected to be $10,200,000. In addition, the Company has granted the underwriters a 30-day option to purchase up to an additional 408,000 shares of its common stock at the public offering price, less

underwriting discounts and commissions. All of the shares are to be sold by the Company. The offering is expected to close on or about November 1, 2024, subject to satisfaction of customary closing conditions.

Jones is acting as the sole book-running manager for the offering.

The underwritten public offering is being made pursuant to a shelf registration statement on Form S-3 (File No. 333-273949) (including a base prospectus) previously filed with the Securities and Exchange Commission (the SEC ) on August 11, 2023 and declared effective by the SEC on August 18,

2023. A preliminary prospectus supplement and the accompanying prospectus relating to and describing the terms of the underwritten public offering were filed with the SEC on October 30, 2024. A final prospectus supplement relating to the

offering will be filed with the SEC and will be available on the SEC s website at www.sec.gov. When available, electronic copies of the final prospectus supplement and the accompanying prospectus relating to the underwritten public offering may

also be obtained by contacting: JonesTrading Institutional Services LLC, Attention: Equity Capital Markets, 325 Hudson Street, 6th Floor New York, New York 10013; email: ecm@jonestrading.com.

This press release does not constitute an offer to sell or the solicitation of an offer to buy, nor shall there be any sale of these securities in any state

or jurisdiction in which such offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such state or jurisdiction.

CalciMedica is a clinical-stage

biopharmaceutical company focused on developing novel CRAC channel inhibition therapies for inflammatory and immunologic diseases. CalciMedica s proprietary technology targets the inhibition of CRAC channels to modulate the immune response and

protect against tissue cell injury, with the potential to provide therapeutic benefits in life-threatening inflammatory and immunologic diseases for which there are currently no approved therapies. CalciMedica s lead product candidate

Auxora has demonstrated positive and consistent clinical results in multiple completed efficacy clinical trials. CalciMedica has announced data for a Phase 2b trial (called CARPO

NCT04681066) in patients with AP with SIRS and completed a Phase 2 trial (called CARDEA NCT04345614) in patients with COVID pneumonia. The Company is currently conducting a Phase 2 trial (called KOURAGE

NCT06374797) in patients with AKI with associated AHRF with data expected in 2025 and continuing to support the ongoing Phase 1/2 trial (called CRSPA NCT04195347) in patients with AIPT with data expected in 2025. CalciMedica

was founded by scientists from Torrey Pines Therapeutics and the Harvard CBR Institute for Biomedical Research, and is headquartered in La Jolla, CA.

Forward-Looking Statements

Any statements in this press release about future expectations, plans and prospects for CalciMedica, including statements about the timing and completion of

the underwritten public offering, and other statements containing the words anticipate, believe, estimate, expect, intend, may, plan, predict,

project, target, potential, will, would, could, should, continue, and similar expressions, constitute forward-looking statements within the meaning of

The Private Securities Litigation Reform Act of 1995. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including: CalciMedica s inability, or the inability of

the underwriter, to satisfy the conditions to closing for the underwritten public offering; and economic, business, competitive, and/or regulatory factors affecting the business of CalciMedica generally. Additional risks and uncertainties that

could cause actual outcomes and results to differ materially from those contemplated by the forward-looking statements are included under the caption Risk Factors in CalciMedica s Quarterly Report on Form 10-Q for the quarter ended June 30, 2024 filed with the SEC on August 12, 2024 and other filings CalciMedica makes with the SEC from time to time and available at www.sec.gov. All forward-looking

statements contained in this press release speak only as of the date on which they were made. CalciMedica undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were

made, except as required by law.

CalciMedica Contact:

Sarah Sutton/Kevin Murphy