Onconetix, Inc. Announces 1-for-5 Reverse Stock Split

Onconetix, Inc. Announces 1-for-5 Reverse Stock Split

CINCINNATI, Ohio, March 23, 2026 (GLOBE NEWSWIRE) -- Onconetix, Inc.

(NASDAQ: ONCO) ("Onconetix" or the "Company"), a commercial-stage biotechnology company focused on the research,

development, and commercialization of innovative solutions for men's health and oncology, today announced that its Board of Directors

(the "Board of Directors" or "Board") has approved a 1-for-5 reverse stock split of its outstanding shares of

common stock, to be effective as of 12:01 a.m. Eastern Time on March 25, 2026.

On February 3, 2026, Onconetix held a special meeting of stockholders

(the "Special Meeting"), at which the Company's stockholders approved a proposal to effect a reverse split, at a ratio

in the range of 1-for-2 to 1-for-50, at any time prior to the one-year anniversary date of the Special Meeting, with such ratio to be

determined by the Board without further approval or authorization of the stockholders. Since the receipt of such stockholder approval,

the Company's Board of Directors has determined to fix a split ratio of 1-for-5 shares. The Company's common stock will begin

trading on a reverse stock split-adjusted basis at the opening of the market on March 25, 2026. Following the reverse stock split, the

Company's common stock will continue to trade on The Nasdaq Capital Market under the symbol "ONCO" under the new CUSIP

number 68237Q 302. The reverse stock split is intended to enable the Company to maintain compliance with the minimum bid price requirement

of $1.00 per share of common stock for continued listing on The Nasdaq Capital Market.

At the effective time of the reverse split, every 5 issued and outstanding

shares of the Company's common stock will be converted automatically into one share of the Company's common stock without

any change in the par value per share. No fractional shares will be issued in connection with the reverse stock split, and fractional

shares resulting from the reverse stock split will be canceled with the holders thereof receiving cash compensation. The amount of compensation

will be determined by multiplying the fractional share by the closing price per share of the Company's common stock on The Nasdaq

Capital Market at the close of business on the trading day prior to the effective date of the reserve stock split, or March 24, 2026.

The reverse split will have no effect on the number of authorized shares of the Company's common stock, and the ownership percentage

of each stockholder will remain unchanged other than as a result of fractional shares. The reverse stock split will additionally apply

to the Company's common stock issuable upon exercise or conversion of the Company's equity awards, convertible preferred stock

and warrants, as well as the applicable exercise price.

The reverse stock split will reduce the number of outstanding shares

of the Company's common stock from approximately 3.6 million to approximately 0.7 million.

About Onconetix, Inc.

Onconetix (Nasdaq: ONCO) is a commercial stage biotechnology company

focused on the research, development and commercialization of innovative solutions for men's health and oncology. Onconetix owns

Proclarix , an in vitro diagnostic test for prostate cancer originally developed by Proteomedix and approved for sale in the European

Union ("EU") under the IVDR, which it anticipates will be marketed in the U.S. as a lab developed test ("LDT")

through its license agreement with Labcorp. For more information, visit www.onconetix.com.

Forward-Looking Statements

Certain statements in this press release are forward-looking within

the meaning of the Private Securities Litigation Reform Act of 1995. These statements may be identified by the use of forward-looking

words such as "anticipate," "believe," "forecast," "estimate," "expect," and

"intend," among others. These forward-looking statements (including, without limitation, statements regarding the timing and

effectiveness of the anticipated reverse split and compliance with applicable Nasdaq continued listing requirements) are based on Onconetix's

current expectations and actual results could differ materially. There are a number of factors that could cause actual events to differ

materially from those indicated by such forward-looking statements. These factors include, but are not limited to, market and other conditions;

our ability to comply with the continued listing requirements of, and remain trading on, the Nasdaq Stock Market, LLC; our

ability to consummate the transaction on a timely basis as contemplated by the Share Exchange Agreement with Realbotix, LLC ("Realbotix"

and the "Share Exchange Agreement" and the transactions contemplated therein, the "Realbotix Transaction") and

the anticipated benefits of the Realbotix Transaction; our ability to complete the Realbotix Transactions on the same term

as contemplated in the Share Exchange Agreement; our ability to successfully integrate our business and Realbotix's

business in the expected timeframe; risks related to unexpected market disruptions that may cause major losses to us not anticipated under

the Share Exchange Agreement; risks related to pending Realbotix Transactions that may divert the attention of our management; the failure

to obtain and maintain the necessary regulatory approvals to market and commercialize Onconetix's products; risks related to the

Company's ability to obtain and maintain intellectual property protection for its current products; and the Company's reliance

on third parties, including manufacturers and logistics companies. As with any commercial-stage pharmaceutical product or any product

candidate under clinical development, there are significant risks in the development, regulatory approval and commercialization of biotechnology

products. Onconetix does not undertake an obligation to update or revise any forward-looking statement. Investors should read the risk

factors set forth in Onconetix's Annual Report on Form 10-K, filed with the SEC on March 13, 2026 and periodic reports filed with

the SEC on or after the date thereof. All of Onconetix's forward-looking statements are expressly qualified by all such risk factors

and other cautionary statements. The information set forth herein speaks only as of the date thereof.

For more information:

201 E. Fifth Street, Suite 1900

Cincinnati, OH 45202

Phone: (513) 620-4101

Investor Contact Information:

Onconetix Investor Relations

Email: investors@onconetix.com