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Onco360® Has Been Selected as a National Specialty Pharmacy Provider for JYLAMVO® (methotrexate) Oral Solution

Key Takeaway: Onco360 has been chosen as the national specialty pharmacy provider for JYLAMVO, an oral solution of methotrexate used to treat various cancers and chronic conditions. This partnership aims to enhance patient support and accessibility to the medication. JYLAMVO is stable at room temperature and addresses the current shortages of methotrexate in other forms. However, it is contraindicated for certain patients and carries risks of serious adverse reactions.
Price reaction · baseline $60.88 (2026-06-03 close) · hit pre-market · clean, no other BTSG news in the window
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POSITIVE FACTORS

  • Onco360 selected as national pharmacy partner for JYLAMVO.
  • JYLAMVO offers an easy-to-administer oral solution.
  • The solution remains stable at room temperature for 90 days.
  • Supports treatment for various cancers and chronic immune conditions.

CONCERNS & RISKS

  • Methotrexate has experienced shortages in other dosage forms.
  • Serious adverse reactions, including death, have been reported.

Full Press Release Details

Louisville, KY – June 4, 2026 – Onco360 ® , the nation’s leading independent Specialty Pharmacy, has been selected as the national pharmacy partner by Shorla Oncology for JYLAMVO ® (methotrexate) , indicated for the treatment of adults and pediatric patients with acute lymphoblastic leukemia (ALL), mycosis fungoides, adults with rheumatoid arthritis, adults with relapsed or refractory non-Hodgkin lymphoma, pediatric patients with polyarticular juvenile idiopathic arthritis, and adults with severe psoriasis. 1
“Supporting therapies that serve patients across multiple cancers and chronic immune conditions reflects our commitment to meeting patients where they are in their treatment journey,” said Benito Fernandez, Chief Commercial Officer. “Working alongside Shorla Oncology, we are proud to help deliver this oral solution along with the personalized pharmacy support patients and providers depend on.”
JYLAMVO ® inhibits dihydrofolic acid reductase. Dihydrofolates must be reduced to tetrahydrofolates by this enzyme before they can be utilized as carriers of one-carbon groups in the synthesis of purine nucleotides and thymidylate; therefore, JYLAMVO ® interferes with DNA synthesis, repair, and cellular replication.
JYLAMVO ® is an easy-to-administer, orange-flavored oral solution of methotrexate that eliminates the need for crushing or splitting pills or compounding into a liquid formulation. Methotrexate has recently suffered shortages in other dosage forms. JYLAMVO ® is an alternative solution that offers advantages over similar drugs because it remains stable at room temperature and does not require cold chain storage. Once opened, JYLAMVO ® is stable at room temperature (68°F to 77°F) for up to 90 days.
JYLAMVO ® is contraindicated in pregnant women for treatment of non-neoplastic diseases and patients with a history of severe hypersensitivity reactions, including anaphylaxis, to methotrexate. Serious adverse reactions, including death, have been reported with methotrexate. Closely monitor for infections and adverse reactions of the bone marrow, gastrointestinal tract, liver, lungs, skin, and kidneys. Withhold or discontinue JYLAMVO ® as appropriate.
Please read the full prescribing information for JYLAMVO ® .
About Onco360 Oncology Pharmacy Onco360 is the nation’s largest independent Oncology Pharmacy and clinical support services company. Onco360 was founded in 2003 to bring together the stakeholders involved in the cancer treatment process and serve the specialized needs of oncologists, patients, hospitals, cancer centers of excellence, manufacturers, health plans, and payers. It dispenses nationally through its network of URAC-, and ACHC-accredited Oncology Pharmacies. Onco360 is headquartered in Louisville, Kentucky, and is a flagship specialty pharmacy brand of PharMerica Corporation, a leading institutional pharmacy, specialty infusion, and hospital services company servicing healthcare facilities in the United States. For more information about Onco360, please visit Onco360.com .
Benito Fernandez, Chief Commercial Officer Benito.fernandez@onco360.com 516-640-1332
References [1]JYLAMVO ® (methotrexate) [Package Insert]. Cambridge, MA. Shorla Oncology. 2024.

Frequently Asked Questions

What is JYLAMVO used for?

JYLAMVO is used to treat various conditions including acute lymphoblastic leukemia and rheumatoid arthritis.

What are the benefits of JYLAMVO?

JYLAMVO is an easy-to-administer oral solution that remains stable at room temperature.

Who is Onco360?

Onco360 is the largest independent oncology pharmacy in the U.S., providing clinical support services.

What are the risks associated with JYLAMVO?

JYLAMVO can cause serious adverse reactions, including infections and hypersensitivity reactions.

Last updated: Jun 4, 2026