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Benitec Biopharma to Provide Phase 1b/2a Clinical Study Update for BB-301 in Oculopharyngeal Muscular Dystrophy

Key Takeaway: Benitec Biopharma announced an upcoming update on its Phase 1b/2a clinical study of BB-301 for Oculopharyngeal Muscular Dystrophy (OPMD). The update will cover six patients from the initial cohort. The webcast is scheduled for November 3, 2025, at 8:00 am EST, reflecting the company's commitment to transparency in its clinical trials.
Price reaction · baseline $16.36 (2025-10-31 close) · 4 other BNTC headline(s) in the window, move may be shared
day 0 close
-3.1%
day 1
-4%
day 3 · peak
-26.7%

Market Sentiment Analysis

POSITIVE FACTORS

  • Benitec Biopharma is advancing its innovative gene therapy platform.
  • The update on the Phase 1b/2a study indicates progress in treating OPMD.
  • The company is focused on developing solutions for serious health conditions.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+36%
120-day peak, hindsight
Typical move
8.7%
average across 3 past catalysts
Cash runway
~38 mo
Minimal dilution risk
Lead asset
BB-401
Phase 2 · Head and Neck Squamous Cell Carcinoma

Full Press Release Details

HAYWARD, Calif., Nov. 02, 2025 (GLOBE NEWSWIRE) -- Benitec Biopharma Inc. (NASDAQ: BNTC) (“Benitec” or the “Company”), a clinical-stage, gene therapy-focused, biotechnology company developing novel genetic medicines based on its proprietary “Silence and Replace” DNA-directed RNA interference (“ddRNAi”) platform, today announced that it will provide an update on the six treated patients from Cohort 1 of its Phase 1b/2a Clinical Study of BB-301 being investigated for the treatment of Oculopharyngeal Muscular Dystrophy (OPMD).

Webcast details:Date:November 3, 2025Time:8:00 am ESTTo register for the webcast, please clickhere.

AboutBenitecBiopharmaInc.Benitec Biopharma Inc. (“Benitec” or the “Company”) is a clinical-stage biotechnology company focused on the advancement of novel genetic medicines with headquarters in Hayward, California. The proprietary “Silence and Replace” DNA-directed RNA interference platform combines RNA interference, or RNAi, with gene therapy to create medicines that simultaneously facilitate sustained silencing of disease-causing genes and concomitant delivery of wildtype replacement genes following a single administration of the therapeutic construct. The Company is developing Silence and Replace-based therapeutics for chronic and life-threatening human conditions including Oculopharyngeal Muscular Dystrophy (OPMD). A comprehensive overview of the Company can be found on Benitec’s website atwww.benitec.com.

InvestorRelationsContact:Irina KofflerLifeSci AdvisorsTel: (917) 734-7387ikoffler@lifesciadvisors.com

Frequently Asked Questions

What is the focus of Benitec Biopharma?

Benitec Biopharma focuses on developing novel genetic medicines using its ddRNAi platform.

When will the update on BB-301 be provided?

The update on BB-301 will be provided on November 3, 2025, at 8:00 am EST.

What condition is BB-301 targeting?

BB-301 is being investigated for the treatment of Oculopharyngeal Muscular Dystrophy (OPMD).

How many patients are included in the update?

The update will cover six treated patients from Cohort 1 of the study.

Last updated: Nov 3, 2025