Applied DNA Sciences Announces Pricing of Upsized $12.0 Million Underwritten Public Offering

Applied DNA Sciences

Announces Pricing of Upsized $12.0 Million Underwritten Public Offering

STONY BROOK, N.Y., November 13, 2019 - Applied DNA Sciences, Inc. (NASDAQ:

APDN) ("Applied DNA" or the "Company") a leader in Polymerase Chain Reaction (PCR)-based DNA manufacturing

for product authenticity, traceability solutions and nucleic acid-based biotherapeutic research, today announced the pricing of

an underwritten public offering of 2,285,000 shares of its common stock and warrants to purchase up to an aggregate of 2,285,000

shares of common stock. Each share of common stock is being sold together with one warrant to purchase one share of common stock

at a combined effective price to the public of $5.25 per share and accompanying warrant. Gross proceeds, before underwriting discounts

and commissions and estimated offering expenses, are expected to be approximately $12.0 million, not including any amounts received

upon exercise of the warrants.

The warrants will be immediately

exercisable at a price of $5.25 per share of common stock and will expire five years from the date of issuance. The shares of

common stock and the accompanying warrants, can only be purchased together in the offering, but will be issued separately. The

offering is expected to close on or about November 15, 2019, subject to customary closing conditions.

Maxim Group LLC is acting

as the book-running manager and Joseph Gunnar & Co. LLC is acting as a co-manager in connection with the offering.

Applied DNA has granted

the underwriters a 45-day option to purchase up to an additional 342,750 shares of common stock and/or warrants to purchase up

to 342,750 shares of common stock, at the public offering price less discounts and commissions.

The Securities and Exchange

Commission (the "SEC") declared effective a registration statement on Form S-1 (File No. 333-233830) relating to these

securities on November 13, 2019. A final prospectus relating to the offering will be filed with the SEC and will be available

on the SEC's website at http://www.sec.gov. The offering is being made only by means of a prospectus forming part of the effective

registration statement. Electronic copies of the prospectus relating to this offering, when available, may be obtained from Maxim

Group LLC, 405 Lexington Avenue, 2nd Floor, New York, NY 10174, at (212) 895-3745. Before investing in this offering, interested

parties should read in its entirety the registration statement that the Company has filed with the SEC, which provides additional

information about the Company and this offering.

This press release shall

not constitute an offer to sell, or the solicitation of an offer to buy, nor may there be any sale of these securities in any

state or jurisdiction in which such an offer, solicitation or sale would be unlawful prior to registration or qualification under

the securities laws of any such state or jurisdiction.

About Applied DNA Sciences

Applied DNA is a provider of molecular

technologies that enable supply chain security, anti-counterfeiting and anti-theft technology, product genotyping, and pre-clinical

nucleic acid-based therapeutic drug candidates.

life real and safe by providing innovative, molecular-based technology solutions and services that can help protect products,

brands, entire supply chains, and intellectual property of companies, governments and consumers from theft, counterfeiting, fraud

Visit adnas.com for more information.

listed on NASDAQ under the symbol APDN, and warrants are listed under the symbol APDNW.

Forward-Looking Statements

The statements made by Applied DNA in

this press release may be "forward-looking" in nature within the meaning of the Private Securities Litigation Reform

Act of 1995. Forward-looking statements describe Applied DNA's future plans, projections, strategies and expectations, and

are based on assumptions and involve a number of risks and uncertainties, many of which are beyond the control of Applied DNA.

Actual results could differ materially from those projected due to the substantial doubt relating to Applied DNA's ability

to continue as a going concern, our ability to successfully enter into commercial contracts for the implementation of our CertainT

platform, the possibility of failure to make timely payment on its outstanding secured convertible notes and resulting enforcement

by noteholders of remedies on collateral which includes substantially all of Applied DNA's assets, the Company's history

of net losses, limited financial resources, limited market acceptance, the uncertainties inherent in research and development,

future clinical data and analysis, including whether any of Applied DNA's product candidates will advance further in the

preclinical research or clinical trial process, uncertainties relating to its ability to maintain its NASDAQ listing after December

31, 2019 in light of delisting notices received and its recent hearing, and various other factors detailed from time to time in

Applied DNA's SEC reports and filings, including our Annual Report on Form 10-K filed on December 18, 2018, as amended,

and our subsequent quarterly reports on Form 10-Q filed on February 7, 2019, May 9, 2019 and August 13, 2019, and other reports

we file with the SEC, which are available at www.sec.gov. Applied DNA undertakes no obligation to update publicly any forward-looking

statements to reflect new information, events or circumstances after the date hereof to reflect the occurrence of unanticipated

events, unless otherwise required by law.

Investor contact: Sanjay

M. Hurry, LHA Investor Relations, 212-838-3777, shurry@lhai.com