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Supporting more consistent PBMC cryopreservation with CryoStor®
In translational research and cell-based workflows, sample handling decisions made early in the process can have a lasting impact on downstream data quality. For organizations working with peripheral blood mononuclear cells, or PBMCs, cryopreservation is not simply a storage step. It is a critical process parameter that can influence viability, recovery, consistency, and usability after thaw.
That is why BioLife Solutions is pleased to share that Sanguine Bio has standardized on CryoStor for its PBMC cryopreservation workflow .
Sanguine Bio is known for providing high-quality human biospecimens that support translational and clinical research. In recent public content, the company has emphasized the importance of optimized PBMC isolation, processing, cryopreservation, and long-term storage to reduce downstream variability and preserve sample integrity. For a workflow where consistency matters, selecting a defined, ready-to-use cryopreservation medium can help remove unnecessary variability from the process.
“By leveraging CryoStor cryopreservation media, we have found it maintains cellular integrity and viability through the freeze-thaw process, ensuring optimal performance in downstream applications,” Richard Mercado, Associate Director, Biorepository and Lab Operations.
CryoStor CS10 is a serum-free, animal component-free, defined cryopreservation medium containing 10% DMSO and is recommended for a range of sensitive cell types, including human peripheral blood. It is manufactured under cGMP conditions and supported by sterility, endotoxin, and cell-based quality control testing. These attributes make it a strong fit for teams that need a more controlled and reproducible approach to cell preservation.
By standardizing on CryoStor, Sanguine Bio is reinforcing an important principle: biopreservation media should be treated as a purposeful process input, not a background reagent. A standardized medium can help support more consistent handling across operators, sites, and studies while giving researchers greater confidence in the quality of cryopreserved PBMC samples.
As more research and therapy developers seek higher-quality starting materials and stronger process control, decisions around cryopreservation continue to move upstream in importance. Sanguine Bio’s adoption of CryoStor reflects that broader shift toward greater consistency, reliability, and rigor in biospecimen workflows.
BioLife Solutions is proud to support organizations like Sanguine Bio with biopreservation tools designed to help protect cell integrity through freezing, storage, and thawing.
About CryoStor
CryoStor is BioLife Solutions’ line of optimized cryopreservation media designed to provide a protective environment for cells during the freeze-thaw process. CryoStor CS10 is widely used for sensitive cell types and is formulated to support consistent cryopreservation performance in research and clinical workflows.