Full Press Release Details
AI Announces Issuance of U.S. Patent Protecting Novel Prodrugs of Mebendazole and Their Use in Treating Cancer
compounds show improved bioavailability relative to mebendazole
MD - July 25, 2023 - BullFrog AI Holdings, Inc. (NASDAQ: BFRG; BFRGW) ("BullFrog AI" or the "Company"),
a precision medicine company using artificial intelligence (AI) and machine learning to enable the successful development of pharmaceuticals
and biologics, today announced that the United States Patent and Trademark Office (USPTO) will, on August 1, 2023, issue U.S. Patent
No. 11,712,435 protecting the Company's novel prodrugs derived from mebendazole and their use in treating cancers and other diseases.
The patented compounds exhibit improved solubility and oral bioavailability relative to the parent drug, thereby addressing a key difficulty
encountered in evaluating the potential use of mebendazole for oncology indications.
Patent No. 11,712,435 represents the first issued patent resulting from intellectual property BullFrog AI licensed from Johns
Hopkins University in October 2022. BullFrog AI's exclusive, worldwide, royalty-bearing license includes the rights to commercialize
prodrugs of mebendazole that demonstrate improved solubility and bioavailability relative to the parent compound.
patent grant further strengthens intellectual property protection of our carefully curated and strategically acquired licensed product
portfolio," said Vin Singh, founder and CEO of BullFrog AI. "Mebendazole has shown promise in treating various types of cancer,
and these N-substituted prodrugs of mebendazole demonstrate significantly improved solubility and bioavailability relative to the parent
compound, enhancing their therapeutic potential and improving the likelihood of clinical success. We look forward to working with strategic
partners to monetize this promising asset for the treatment of glioblastoma and other oncology indications."
AI is a precision medicine company using AI and machine learning to enable the successful development of pharmaceuticals and biologics
by predicting which patients will respond to therapies in development. Through its collaborations with leading research institutions,
including Johns Hopkins University, BullFrog AI is at the forefront of AI-driven drug development using its proprietary bfLEAP
artificial intelligence platform. BullFrog AI is deploying bfLEAP for use at several critical stages of development with the intention
of streamlining data analytics in therapeutics development, decreasing the overall development costs by decreasing failure rates for
more information visit BullFrog AI at:
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