Recent Updates
Recently added Catalysts
BCAB Positive Sentiment

BioAtla to Present Clinical Data for Mecbotamab Vedotin (BA3011) in Soft Tissue Sarcoma at SITC 2025

Key Takeaway: BioAtla, Inc. announced that clinical data for its investigational ADC, mecbotamab vedotin (BA3011), will be presented at the SITC 2025 Annual Meeting. The presentation will highlight a median overall survival of 21.5 months among patients with treatment-refractory leiomyosarcoma, liposarcoma, and undifferentiated pleomorphic sarcoma. The event will take place from November 5-9, 2025, in National Harbor, MD.
Price reaction · baseline $33.135 (2025-10-02 close) · hit pre-market · clean, no other BCAB news in the window
day 0 close · peak
+4.7%

Market Sentiment Analysis

POSITIVE FACTORS

  • Clinical data shows promising median overall survival of 21.5 months.
  • Presentation at a prestigious conference indicates recognition in the field.
  • Innovative AXL-targeting ADC may provide new treatment options for sarcoma patients.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+117%
120-day peak, hindsight
Typical move
8.3%
average across 6 past catalysts
Cash runway
~11 mo
Medium dilution risk
Lead asset
CAB-AXL-ADC
Phase 2 · Non-Small-Cell Lung Cancer

Full Press Release Details

SAN DIEGO, Oct. 03, 2025 (GLOBE NEWSWIRE) --BioAtla, Inc. (Nasdaq: BCAB), a global clinical-stage biotechnology company focused on the development of Conditionally Active Biologic (CAB) antibody therapeutics using its proprietary CAB platform for the treatment of solid tumors, today announced that clinical data for its investigational AXL-targeting antibody-drug conjugate (ADC), mecbotamab vedotin (BA3011), will be presented at the upcoming Society for Immunotherapy of Cancer (SITC) 2025 Annual Meeting to be held at National Harbor, MD from November 5-9, 2025.
The presentation, titled“Median OS of 21.5 months among 44 patients with treatment-refractory leiomyosarcoma, liposarcoma, and undifferentiated pleomorphic sarcoma treated with mecbotamab vedotin, an AXL-targeting ADC”, will be delivered byDr. Mihaela DrutaofMoffitt Cancer CenteronFriday, November 7, 2025. The abstract (#523) will be featured in the poster session, with presentation time to be announced.
A copy of the presentation materials can be accessed on the “Publication” section of the Company’s website atwww.bioatla.comonce the presentation has concluded.

About BioAtla®, Inc.

BioAtla is a global clinical-stage biotechnology company with operations in San Diego, California, and in Beijing, China through its contractual relationship with BioDuro-Sundia, a provider of preclinical development services. Utilizing its proprietary CAB platform technology, BioAtla develops novel, reversibly active monoclonal and bispecific antibodies and other protein therapeutic product candidates. CAB product candidates are designed to have more selective targeting, greater efficacy with lower toxicity, and more cost-efficient and predictable manufacturing than traditional antibodies. BioAtla has extensive and worldwide patent coverage for its CAB platform technology and products with greater than 780 active patent matters, more than 500 of which are issued patents. Broad patent coverage in all major markets include methods of making, screening and manufacturing CAB product candidates in a wide range of formats and composition of matter coverage for specific products. To learn more about BioAtla, Inc., visitwww.bioatla.com.

Internal Contact:Richard WaldronChief Financial OfficerBioAtla, Inc.rwaldron@bioatla.com858.356.8945

External Contact:Joyce AllaireLifeSci Advisors, LLCjallaire@lifesciadvisors.com

Frequently Asked Questions

What is mecbotamab vedotin?

Mecbotamab vedotin (BA3011) is an AXL-targeting antibody-drug conjugate developed by BioAtla.

When will the SITC 2025 Annual Meeting take place?

The SITC 2025 Annual Meeting will be held from November 5-9, 2025.

What were the results presented for mecbotamab vedotin?

The presentation will highlight a median overall survival of 21.5 months among patients treated with mecbotamab vedotin.

Who will present the clinical data?

Dr. Mihaela Druta from Moffitt Cancer Center will present the clinical data.

Where can I find the presentation materials?

The presentation materials will be available on BioAtla's website after the presentation.

Last updated: Oct 3, 2025