Full Press Release Details
Biologics Announces Signing of Option to License Revolutionary Bone Growth Factor Nell-1 from UCLA for Use in Osteoporosis
of the Option Would Expand Bone Biologics' Exclusive Rights for Nell-1 Beyond Spinal Fusion
June 14, 2016 / - Bone Biologics (OTCQB: BBLG), an orthobiologic company focused on regenerative medicine, announced today
the signing of an option agreement with UCLA, for an opportunity to exclusively license the use of the revolutionary bone growth
factor Nell-1 in the treatment of osteoporosis.
Bone Biologics is funding the development and formulation of a Nell-1-based product for use as a bone graft substitute focused
on bone regeneration in spinal fusion procedures, also under exclusive license from UCLA. Nell-1 has already demonstrated a unique
ability to form bone in a targeted fashion with a significantly greater safety profile, making it a significantly more attractive
treatment modality than other bone growth factors and implanted devices.
debilitating condition of osteoporosis, the severe loss of bone mass that puts sufferers at increased risk of bone fractures,
is currently treated with drugs. The market for osteoporosis therapies is estimated at over $11bn globally. While most therapies
only help prevent further bone loss by inhibiting the osteoclasts, Nell-1 works by inducing the osteoblasts. Competing drugs are
expensive, and require daily injections.
La Neve, CEO and President of Bone Biologics, noted, "We believe that Nell-1 may have significant advantages over currently-available
osteoporosis therapies. We intend to meet the requirements that would allow Bone Biologics to exercise the option to become the
exclusive licensee for the use of Nell-1 for osteoporosis therapy. These requirements include the demonstration of Nell-1's
ability to target multi-billion-dollar target markets in osteoporosis and the demonstration of efficacy in animals. Given the
development path we are taking with Nell-1 in the spinal fusion market, we expect to be able to build on that experience as we
seek an opportunity to develop Nell-1 for osteoporosis."
Biologics (OTCQB:BBLG) was founded to pursue regenerative medicine for bone.
Biologics Corporation is undertaking groundbreaking work with the three founders and select strategic partners, building on unprecedented
research on the Nell-1 molecule that has produced a significant number of studies and publications in peer reviewed scientific
Biologics is currently focusing its development efforts for its bone graft substitute product on bone regeneration in spinal fusion.
Nell-1 is a recombinant human protein growth factor that is essential for normal bone development.
more information, please visit the company's website at www.bonebiologics.com.
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press release contains forward-looking statements that reflect the Company's current beliefs, expectations or intentions
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forward-looking statements. Words such as "will," "will be," "anticipate," "predict,"
"continue," "future," and similar expressions are intended to identify such forward-looking statements.
These forward-looking statements include, without limitation, the Company's expectations with respect to trading in the
Company's common stock on the OTC Bulletin Board; the next phase of the Company's development and testing work; the
Company's expectation about moving its technology forward and setting the stage for future growth and enhanced shareholder
value; and the future need for regenerative bone solutions. All forward-looking statements involve significant risks and uncertainties
that could cause actual results to differ materially from those expressed or implied in the forward-looking statements, many of
which are generally outside the control of the Company and are difficult to predict. Examples of such risks and uncertainties
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current cash and working capital to fund present and planned operations and financing needs, expansion of and demand for product
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that could cause actual results to differ materially from those expressed or implied in the forward-looking statements can be
found in the most recent current report on Form 10-K, filed with the Securities and Exchange Commission on March 28, 2015 and
Form 10-Q, filed with the Securities and Exchange Commission on May 13, 2016. The Company anticipates that subsequent events and
developments may cause their views and expectations to change. The Company assumes no obligation, and they specifically disclaim
any intention or obligation, to update any forward-looking statements, whether as a result of new information, future events or
Frelick, Chief Operating Officer
Collinson, 714-222-5161
Williams, 310-824-9000