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BridgeBio to Present Primary Results from the Phase 3 CALIBRATE Trial at 2026 ECE

Key Takeaway: BridgeBio Pharma announced it will present primary results from the Phase 3 CALIBRATE trial of encaleret at the 2026 European Congress of Endocrinology. The trial focuses on individuals with autosomal dominant hypocalcemia type 1 (ADH1). Additional presentations will cover genetic testing and quality of life measures related to hypoparathyroidism.

Market Sentiment Analysis

POSITIVE FACTORS

  • BridgeBio is sharing promising results from its Phase 3 CALIBRATE trial.
  • The presentation at a major congress highlights the importance of their research.
  • Encaleret shows potential in restoring mineral homeostasis in ADH1 patients.

Full Press Release Details

PALO ALTO, Calif., May 05, 2026 (GLOBE NEWSWIRE) -- BridgeBio Pharma, Inc. (Nasdaq: BBIO) (“BridgeBio” or the “Company”), a biopharmaceutical company focused on developing medicines for genetic conditions, announced today that additional data in individuals with autosomal dominant hypocalcemia type 1 (ADH1) from CALIBRATE, its Phase 3 study of encaleret, will be shared in an oral presentation at the 2026 European Congress of Endocrinology (ECE) taking place in Prague, Czech Republic on May 9-12, 2026. The Company will also share an additional oral presentation, one poster, and one eposter at the meeting.
Oral Presentations:Encaleret Restores Mineral Homeostasis in ADH1: Primary Results from the Phase 3 CALIBRATE TrialPresenter:Filomena Cetani, M.D., Ph.D., University of Pisa, ITDate & Time:Tuesday, May 12 at 11:50 am CEST
Genetic Testing of Over 400 Individuals with Non-Surgical Hypoparathyroidism Shows Gain-of-FunctionCASRVariants as the Most Common Genetic Cause IdentifiedPresenter:Arun Mathew, BridgeBio Endocrinology, U.S.Date & Time:Tuesday, May 12 at 12:20 pm CEST
Poster:Autosomal Dominant Hypocalcemia Type 1 and Type 2: Baseline Quality of Life Measures in Adult Participants in the CLARIFY Disease Monitoring StudyPresenter:Heide Siggelkow, M.D., University Medical Center of Göttingen, DEPoster ID:P72Date & Time:Sunday, May 10 at 4:55 pm CEST and Monday, May 11 at 5 pm CEST
ePoster:Epidemiology and Clinical Management of ADH1: A Systematic Literature ReviewPresenter:Arun Mathew, BridgeBio Endocrinology, U.S.Poster ID:EP260
About BridgeBioBridgeBio exists to develop transformative medicines for genetic conditions. Millions of people worldwide living with genetic conditions lack treatment options, often because drug development for small patient populations can be commercially challenging. We aim to bridge the gap between advancements in genetic science and meaningful medicines for underserved patient populations. Our decentralized, hub-and-spoke model is designed for speed, precision, and scalability. Autonomous and empowered teams focus on individual conditions, while a central hub provides the clinical, regulatory, and commercial capabilities needed to bring innovation to market. For more information, visitbridgebio.comand follow us onLinkedIn,X,Facebook,Instagram,YouTube, andTikTok.

BridgeBio Media Contact:Bubba Murarka, Executive Vice Presidentcontact@bridgebio.com(650)-789-8220

BridgeBio Investor Contact:Chinmay Shukla, Senior Vice President, Strategic Financeir@bridgebio.com

Frequently Asked Questions

What is the CALIBRATE trial?

The CALIBRATE trial is a Phase 3 study evaluating encaleret for treating autosomal dominant hypocalcemia type 1.

When will the results be presented?

The results will be presented on May 12, 2026, at the European Congress of Endocrinology.

Who is presenting the CALIBRATE trial results?

Filomena Cetani, M.D., Ph.D., from the University of Pisa, will present the results.

What additional presentations will BridgeBio make?

BridgeBio will also present a poster and an eposter related to ADH1 and hypoparathyroidism.

Last updated: May 5, 2026