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Atara Biotherapeutics Announces Third Quarter Financial Results and Operational Progress Tab-cel Prescription Drug User Fee Act (PDUFA) Target Action Date of

Key Takeaway: Atara Biotherapeutics reported its third quarter financial results and detailed its progress regarding the Biologics License Application (BLA) for tab-cel, aimed at treating EBV+ PTLD. The BLA has been accepted by the FDA with a target action date set for January 10, 2026. Additionally, Atara has transitioned much of its tab-cel operations to Pierre Fabre, allowing for potential milestone payments. However, the company announced a workforce reduction of approximately 29%, which may affect its strategic execution moving forward.

Market Sentiment Analysis

POSITIVE FACTORS

  • Atara is progressing towards the FDA's acceptance of its Biologics License Application (BLA) for tab-cel.
  • Potential $40 million milestone payment from Pierre Fabre upon BLA approval could enhance financial position.
  • The company is strategically transitioning activities to Pierre Fabre, streamlining operations.

CONCERNS & RISKS

  • Atara's workforce reduction by 29% could impact its operational capacity.
  • The financial outlook shows a significant loss for the third quarter, raising concerns about future profitability.
  • There are inherent risks associated with regulatory approval and the pharmaceutical development process.

Full Press Release Details

Atara Biotherapeutics Announces Third Quarter Financial Results and Operational Progress
Tab-cel Prescription Drug User Fee Act (PDUFA) Target Action Date of January 10, 2026
Atara has completed the transfer of substantially all tab-cel activities, including BLA sponsorship, and associated costs to Pierre Fabre
Approval of BLA would unlock a $40 Million milestone payment from Pierre Fabre Laboratories
THOUSAND OAKS, Calif.-(BUSINESS WIRE)- Atara Biotherapeutics, Inc. (Nasdaq: ATRA), a leader in
T-cell immunotherapy, leveraging its novel allogeneic Epstein-Barr virus (EBV) T-cell platform to develop transformative therapies for patients with cancer and
autoimmune diseases, today reported financial results for the third quarter 2025 and business updates.
Tabelecleucel (tab-cel or Ebvallo ) for Post-Transplant Lymphoproliferative Disease (PTLD)
The U.S. Food and Drug Administration (FDA) has accepted the filing of Atara's Biologics License Application (BLA) for tabelecleucel (tab-cel ) indicated as monotherapy for treatment of adult and pediatric patients two years of age and older with Epstein-Barr virus positive post-transplant lymphoproliferative disease (EBV+ PTLD) who
have received at least one prior therapy. There are no FDA approved therapies in this treatment setting.
The BLA has been granted Priority Review with a
Class 2 Resubmission Prescription Drug User Fee Act (PDUFA) target action date of January 10, 2026.
Atara expects to receive an additional
$40 million milestone payment from Pierre Fabre Laboratories contingent upon FDA approval of the tab-cel BLA.
In October, Atara completed the
transfer of regulatory activities, including BLA sponsorship, to Pierre Fabre Laboratories. Atara will continue to support Pierre Fabre Laboratories, at Pierre Fabre Laboratories expense, with certain regulatory activities related to the BLA.
Substantially all operational activities and associated costs related to tab-cel have been transitioned to Pierre Fabre Laboratories.
Strategic Alternatives Evaluation: As previously communicated, Atara continues to actively explore and assess potential strategic
alternatives with the goal of maximizing shareholder value.
Organizational Restructuring: In October 2025, Atara announced a reduction in its
workforce that impacted approximately 29% of its current employees, retaining approximately 15 employees essential to executing on the Company's strategic priorities.
Third Quarter 2025 Financial Results:
2025 Outlook and Cash Runway:
About Atara Biotherapeutics, Inc.
Atara is harnessing the natural power of the immune system to develop
off-the-shelf cell therapies for difficult-to-treat cancers and autoimmune conditions
that can be rapidly delivered to patients from inventory. With cutting-edge science and differentiated approach, Atara is the first company in the world to receive regulatory approval of an allogeneic T-cell
immunotherapy. Our advanced and versatile T-cell platform does not require T-cell receptor or HLA gene editing and forms the basis of a diverse portfolio of
investigational therapies that target EBV, the root cause of certain diseases. Atara is headquartered in Southern California. For more information, visit atarabio.com and
follow @Atarabio on X and LinkedIn.
Forward-Looking Statements
This press release contains or may imply "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933 and
Section 21E of the Securities Exchange Act of 1934. For example, forward-looking statements include statements regarding: (1) the development, timing and progress of tab-cel, including the timing for FDA review of the resubmission of the
BLA, the potential characteristics and benefits of tab-cel, and the results of, and prospects for, the global partnership with Pierre Fabre Medicament involving tab-cel, and the potential financial benefits to Atara as a result of the global
partnership with Pierre Fabre Medicament, including the receipt, timing and amount of any payments to be received by Atara thereunder; (2) Atara's cash runway, receipt of potential milestone payments, and estimated reduction in operating
expenses; and (3) Atara's evaluation of strategic alternatives and ability to consummate one or more strategic transactions. Because such statements deal with future events and are based on Atara's current expectations, they are
subject to various risks and uncertainties and actual results, performance or achievements of Atara could differ materially from those described in or implied by the statements in this press release. These forward-looking statements are subject to
risks and uncertainties, including, without limitation, risks and uncertainties associated with the costly and time-consuming pharmaceutical product development process and the uncertainty of clinical success; risks related to FDA's review of
the resubmitted BLA for tab-cel; our ability to access capital, and the sufficiency of Atara's cash resources and access to additional capital on favorable terms or at all; the timing of the strategic review process; whether Atara will pursue
any strategic alternatives; in the event Atara pursues a strategic alternative, that the strategic alternative may not be attractive or ultimately consummated; whether any strategic alternative will result in additional value for Atara and its
stockholders; whether the process will have an adverse impact on Atara and other risks and uncertainties affecting Atara, including those discussed in Atara's filings with the Securities and Exchange Commission, including in the "Risk
Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations" sections of the Company's most recently filed periodic reports on Form 10-K
and Form 10-Q and subsequent filings and in the documents incorporated by reference therein. Except as otherwise required by law, Atara disclaims any intention or obligation to update or revise any
forward-looking statements, which speak only as of the date hereof, whether as a result of new information, future events or circumstances or otherwise.
ATARA BIOTHERAPEUTICS, INC.
Condensed Consolidated Balance Sheets
September 30, 2025 December 31, 2024
Assets
Current assets:
Cash and cash equivalents $ 5,742 $ 25,030
Short-term investments 7,970 17,466
Restricted cash - 146
Accounts receivable 1,913 1,482
Inventories - 10,655
Other current assets 2,807 10,115
Total current assets 18,432 64,894
Property and equipment, net 147 1,294
Operating lease assets 10,707 39,807
Other assets 881 3,103
Total assets $ 30,167 $ 109,098
Liabilities and stockholders' equity (deficit)
Current liabilities:
Accounts payable $ 318 $ 4,367
Accrued compensation 2,067 6,589
Accrued research and development expenses 342 7,984
Deferred revenue 1,011 95,092
Liability related to the sale of future revenues - current portion 9,670 382
Other current liabilities 4,649 20,160
Total current liabilities 18,057 134,574
Operating lease liabilities - long-term 15,005 29,914
Liability related to the sale of future revenues - long-term 31,976 38,624
Other long-term liabilities 1,763 3,269
Total liabilities 66,801 206,381
Commitments and contingencies (Note 9)
Stockholders' equity (deficit):
Common stock-$0.0001 par value, 500,000 shares authorized as of September 30, 2025 and December 31, 2024; 7,210 and 5,859 shares issued and outstanding as of September 30, 2025 and December 31, 2024, respectively 1 1
Additional paid-in capital 1,981,822 1,957,261
Accumulated other comprehensive income (loss) 2 8
Accumulated deficit (2,018,459 ) (2,054,553 )
Total stockholders' equity (deficit) (36,634 ) (97,283 )
Total liabilities and stockholders' equity (deficit) $ 30,167 $ 109,098
ATARA BIOTHERAPEUTICS, INC.
Condensed Consolidated Statements of Operations and Comprehensive Loss
thousands, except per share amounts)
Three Months Ended September 30, Nine Months Ended September 30,
2025 2024 2025 2024
Commercialization revenue $ 3,453 $ 40,190 $ 119,177 $ 96,187
Costs and operating expenses:
Cost of commercialization revenue 115 7,602 21,108 14,214
Research and development expenses 2,925 43,924 37,668 122,762
General and administrative expenses 3,987 10,421 21,976 30,446
Total costs and operating expenses 7,027 61,947 80,752 167,422
Income (loss) from operations (3,574 ) (21,757 ) 38,425 (71,235 )
Other income (expense), net:
Interest income 204 459 583 1,513
Interest expense (909 ) (1,183 ) (2,898 ) (3,598 )
Other income (expense), net 4 555 15 617
Total other income (expense), net (701 ) (169 ) (2,300 ) (1,468 )
Income (loss) before provision for (benefit from) income taxes (4,275 ) (21,926 ) 36,125 (72,703 )
Provision for (benefit from) income taxes 28 (17 ) 31 7
Net income (loss) $ (4,303 ) $ (21,909 ) $ 36,094 $ (72,710 )
Other comprehensive gain (loss):
Unrealized gain (loss) on available-for-sale securities 2 36 (6 ) 226
Comprehensive income (loss) $ (4,301 ) $ (21,873 ) $ 36,088 $ (72,484 )
Basic earnings (loss) per common share $ (0.32 ) $ (2.93 ) $ 2.96 $ (11.34 )
Diluted earnings (loss) per common share $ (0.32 ) $ (2.93 ) $ 2.93 $ (11.34 )
Basic and diluted weighted-average shares outstanding 13,564 7,466 12,185 6,414
Diluted weighted-average shares outstanding 13,564 7,466 12,319 6,414
Investor and Media Relations
Sr. Director, Strategy and Operations

Frequently Asked Questions

What is the PDUFA date for Atara's tab-cel?

The PDUFA target action date for tab-cel is January 10, 2026.

What milestone payment is expected from Pierre Fabre?

Atara anticipates a $40 million milestone payment upon tab-cel BLA approval.

What did Atara transfer to Pierre Fabre?

Atara transferred virtually all tab-cel activities and BLA sponsorship to Pierre Fabre.

What recent workforce change did Atara announce?

Atara announced a 29% reduction in its workforce in October 2025.

What is tab-cel used to treat?

Tab-cel is indicated for Epstein-Barr virus positive post-transplant lymphoproliferative disease.

Last updated: Nov 12, 2025