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Results of 2025 Annual General Meeting MELBOURNE, AUSTRALIA AND SAN FRANCISCO, USA - 21 November 2025: In accordance with ASX Listing rule 3.13.2 and Section 251AA of the Corporations Act 2001 (Cth), the attached informa

Key Takeaway: Alterity Therapeutics Limited held its Annual General Meeting on November 21, 2025, where shareholders approved several resolutions. The company has shown positive clinical data for its lead asset, ATH434, particularly in treating Multiple System Atrophy. Alterity continues to focus on developing innovative therapies for neurodegenerative diseases and has a robust drug discovery platform. CEO David Stamler authorized this announcement, highlighting the company's commitment to addressing significant medical needs.

Market Sentiment Analysis

POSITIVE FACTORS

  • Shareholders of Alterity Therapeutics approved resolutions at the AGM.
  • Discussed positive data for lead asset ATH434 in multiple trials.
  • The company focuses on developing therapies for neurodegenerative diseases.

Full Press Release Details

Results of 2025 Annual General Meeting
MELBOURNE, AUSTRALIA AND SAN FRANCISCO, USA
- 21 November 2025: In accordance with ASX Listing rule 3.13.2 and Section 251AA of the Corporations Act 2001 (Cth), the attached
information is provided in relation to the resolutions passed by the shareholders of Alterity Therapeutics Limited (ASX: ATH, NASDAQ:
ATHE) ("Alterity" or "the Company") at its Annual General Meeting held on 21 November 2025.
About Alterity Therapeutics Limited
Alterity Therapeutics is a clinical
stage biotechnology company dedicated to creating an alternate future for people living with neurodegenerative diseases. The Company is
initially focused on developing disease modifying therapies in Parkinson's disease and related disorders. Alterity has demonstrated
clinically meaningful efficacy for its lead asset, ATH434, in a randomized, double blind, placebo-controlled Phase 2 clinical trial in
participants with Multiple System Atrophy (MSA), a rare and rapidly progressive Parkinsonian disorder. ATH434 recently reported positive
data in its open label Phase 2 clinical trial in advanced MSA. In addition, Alterity has a broad drug discovery platform generating patentable
chemical compounds to treat the underlying pathology of neurological diseases. The Company is based in Melbourne, Australia, and San Francisco,
California, USA. For further information please visit the Company's website at www.alteritytherapeutics.com.
Authorisation & Additional information
This announcement was authorised by David Stamler,
CEO of Alterity Therapeutics Limited.
Investors Media
Tara Speranza Casey McDonald
Head of Investor Relations and Communications Tiberend Strategic Advisors, Inc.
tsperanza@alteritytx.com cmcdonald@tiberend.com
+61 (0) 432 961 533 +1 (646) 577-8520
Remy Bernarda
Investor Relations Advisory Solutions
ir@alteritytx.com
+1 (415) 203-6386
Forward Looking Statements
This press release contains
"forward-looking statements" within the meaning of section 27A of the Securities Act of 1933 and section 21E of the Securities
Exchange Act of 1934. The Company has tried to identify such forward-looking statements by use of such words as "expects," "intends,"
"hopes," "anticipates," "believes," "could," "may," "evidences" and "estimates,"
and other similar expressions, but these words are not the exclusive means of identifying such statements.
Important factors that
could cause actual results to differ materially from those indicated by such forward-looking statements are described in the sections
titled "Risk Factors" in the Company's filings with the SEC, including its most recent Annual Report on Form 20-F as
well as reports on Form 6-K, including, but not limited to the following: statements relating to the Company's drug development program,
including, but not limited to the initiation, progress and outcomes of clinical trials of the Company's drug development program, including,
but not limited to, ATH434, and any other statements that are not historical facts. Such statements involve risks and uncertainties, including,
but not limited to, those risks and uncertainties relating to the difficulties or delays in financing, development, testing, regulatory
approval, production and marketing of the Company's drug components, including, but not limited to, ATH434, the ability of the Company
to procure additional future sources of financing, unexpected adverse side effects or inadequate therapeutic efficacy of the Company's
drug compounds, including, but not limited to, ATH434, that could slow or prevent products coming to market, the uncertainty of obtaining
patent protection for the Company's intellectual property or trade secrets, the uncertainty of successfully enforcing the Company's
patent rights and the uncertainty of the Company freedom to operate.
Any forward-looking statement
made by us in this press release is based only on information currently available to us and speaks only as of the date on which it is
made. We undertake no obligation to publicly update any forward-looking statement, whether written or oral, that may be made from time
to time, whether as a result of new information, future developments or otherwise.

Frequently Asked Questions

What is the focus of Alterity Therapeutics?

Alterity Therapeutics is focused on developing therapies for neurodegenerative diseases, particularly Parkinson's disease.

What trial data was recently reported for ATH434?

ATH434 recently reported positive results in an open label Phase 2 trial for advanced MSA.

When was the Annual General Meeting held?

The Annual General Meeting took place on 21 November 2025.

Who authorized the announcement?

The announcement was authorized by David Stamler, CEO of Alterity Therapeutics.

Where is Alterity Therapeutics based?

Alterity Therapeutics is based in Melbourne, Australia, and San Francisco, USA.

Last updated: Nov 21, 2025