Recent Updates
Recently added Catalysts
ARTV Positive Sentiment

Base to Base Biotech Podcast: Natural Killer Cell Therapy

Key Takeaway: In a recent podcast episode, Lisa Guerrettaz from Artiva Biotherapeutics discusses the challenges of current rheumatoid arthritis treatments and the potential of AlloNK® therapy. The conversation highlights the need for more effective and durable solutions in autoimmune disease management, drawing on lessons from previous therapies and CAR-T insights.
Price reaction · baseline $4.68 (2026-01-26 close) · hit pre-market · clean, no other ARTV news in the window
day 0 close · peak
+3.6%

Market Sentiment Analysis

POSITIVE FACTORS

  • Discussion on innovative therapies for rheumatoid arthritis.
  • Focus on developing more durable treatment options.
  • Insights from CAR-T therapies informing new approaches.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+215%
120-day peak, hindsight
Typical move
13.1%
average across 2 past catalysts
Cash runway
~51 mo
Minimal dilution risk
Lead asset
Allogeneic NK Cells
Phase 2 · Refractory Rheumatoid Arthritis (RA)

Full Press Release Details

In rheumatoid arthritis, existing therapies frequently fall short of delivering sustained disease control, despite sequential use of biologic and targeted agents.
In a this episode of the 𝗕𝗮𝘀𝗲 𝘁𝗼 𝗕𝗮𝘀𝗲 𝗕𝗶𝗼𝘁𝗲𝗰𝗵 𝗣𝗼𝗱𝗰𝗮𝘀𝘁, Lisa Guerrettaz, Executive Director, Pharmacology and Translational Science at Artiva Biotherapeutics, discusses how the limitations of currently approved treatments are driving the development of new and potentially more durable therapeutic approaches for autoimmune diseases.
The conversation examines lessons from prior approaches in autoimmune disease, the limitations of current treatment sequencing, and how these insights are informing the clinical development of AlloNK® in rheumatoid arthritis.
The conversation explores:
• Why existing therapies often fail to deliver sustained disease control in rheumatoid arthritis
• What deep B-cell depletion means biologically, and how insights from CAR-T in autoimmune disease have shaped current thinking around immune reset
• How AlloNK is being developed to align depth of immune effect with real-world treatment considerations
Listen here.

Frequently Asked Questions

What are the limitations of current rheumatoid arthritis therapies?

Current therapies often fail to provide sustained disease control despite sequential use.

What is AlloNK®?

AlloNK® is a new therapeutic approach being developed for rheumatoid arthritis.

How does CAR-T therapy relate to autoimmune diseases?

Insights from CAR-T therapies are shaping current strategies for immune reset in autoimmune diseases.

Who is Lisa Guerrettaz?

Lisa Guerrettaz is the Executive Director of Pharmacology and Translational Science at Artiva Biotherapeutics.

Last updated: Jan 27, 2026