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Alumis Announces Proposed Public Offering of Common Stock

Key Takeaway: Alumis Inc. has announced a proposed underwritten public offering of $175 million worth of common stock, with an additional option for underwriters to purchase another $26.25 million in shares. The offering aims to fund the development of its pipeline of targeted therapies for immune-mediated diseases. The company has filed a registration statement with the SEC for the offering, which remains subject to market conditions and uncertainties regarding completion.

Market Sentiment Analysis

POSITIVE FACTORS

  • Alumis is raising $175 million to support its clinical-stage biopharmaceutical development.
  • The company is working on next-generation therapies targeting immune-mediated diseases.
  • The offering demonstrates confidence in Alumis's growth potential and innovative therapies.

CONCERNS & RISKS

  • The proposed offering is subject to market conditions and may not be completed.
  • There is no assurance of the actual size or terms of the offering yet.

Full Press Release Details

SOUTH SAN FRANCISCO, Calif., Jan. 06, 2026 (GLOBE NEWSWIRE) -- Alumis Inc. (Nasdaq: ALMS), a clinical-stage biopharmaceutical company developing next-generation targeted therapies for patients with immune-mediated diseases, today announced its plans to commence an underwritten public offering of $175.0 million of shares of its common stock. All of the shares are being offered by Alumis. In addition, Alumis expects to grant the underwriters a 30-day option to purchase up to an additional $26.25 million of shares of its common stock at the public offering price per share. The proposed offering is subject to market and other conditions, and there can be no assurance as to whether or when the proposed offering may be completed or as to the actual size or terms of the proposed offering.
Morgan Stanley, Leerink Partners, Cantor and Wells Fargo Securities are acting as joint book-running managers for the proposed offering.
The proposed offering is being made pursuant to a shelf registration statement on Form S-3, including a base prospectus, that was previously filed with the Securities and Exchange Commission (the “SEC”) and declared effective by the SEC on August 19, 2025. A preliminary prospectus supplement and accompanying prospectus relating to the proposed offering will be filed with the SEC and will be available for free on the SEC’s website located at http://www.sec.gov. Copies of the preliminary prospectus supplement and the accompanying prospectus relating to the proposed offering may be obtained, when available from: Morgan Stanley & Co. LLC, Attention: Prospectus Department, 180 Varick Street, 2nd Floor, New York, NY 10014, by telephone at (866) 718-1649, or by email at prospectus@morganstanley.com; Leerink Partners LLC, Syndicate Department, 53 State Street, 40th Floor, Boston, MA 02109, by telephone at (800) 808-7525 ext. 6105, or by email at syndicate@leerink.com; Cantor Fitzgerald & Co., Attention: Capital Markets, 110 East 59th Street, 6th Floor, New York, New York 10022, or by email at prospectus@cantor.com; or Wells Fargo Securities, LLC, Attention: Wells Fargo Securities, 90 South 7th Street, 5th Floor, Minneapolis, MN 55402, at 800-645-3751 (option #5) or email a request to WFScustomerservice@wellsfargo.com.
This press release shall not constitute an offer to sell or a solicitation of an offer to buy, nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.
Alumis is a clinical-stage biopharmaceutical company developing next-generation targeted therapies with the potential to significantly improve patient health and outcomes across a range of immune-mediated diseases. Leveraging its proprietary data analytics platform and precision approach, Alumis is developing a pipeline of oral tyrosine kinase 2 inhibitors, consisting of envudeucitinib (or envu, formerly known as ESK-001) for the treatment of systemic immune-mediated disorders, such as moderate-to-severe plaque psoriasis and systemic lupus erythematosus, and A-005 for the treatment of neuroinflammatory and neurodegenerative diseases. In addition, the pipeline includes lonigutamab, a subcutaneously delivered anti–insulin-like growth factor 1 receptor therapy for the treatment of thyroid eye disease, as well as several preclinical programs identified through this precision approach.

Tags

immune-mediated diseases

Frequently Asked Questions

What type of company is Alumis Inc.?

Alumis Inc. is a clinical-stage biopharmaceutical company focused on developing targeted therapies for immune-mediated diseases.

How much is Alumis' public offering worth?

Alumis plans to commence a public offering of $175.0 million in shares.

Who are the underwriters for Alumis' offering?

Morgan Stanley, Leerink Partners, Cantor, and Wells Fargo Securities are the underwriters.

What is Alumis developing for immune-mediated disorders?

Alumis is developing oral tyrosine kinase 2 inhibitors, including envudeucitinib for various disorders.

Where can I find Alumis' preliminary prospectus?

The preliminary prospectus can be accessed on the SEC’s website and from the underwriters.

Last updated: Jan 6, 2026