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Alumis Announces Late-Breaker Psoriasis Phase 2 Data Presentation for Allosteric TYK2 Inhibitor ESK-001 at the American Academy of Dermatology 2024 Annual Meeting

Key Takeaway: Alumis Inc. has announced that it will present late-breaking data from its Phase 2 clinical trial of ESK-001, a selective oral TYK2 inhibitor for moderate-to-severe plaque psoriasis, at the American Academy of Dermatology Annual Meeting. The presentations will include both efficacy and safety results, as well as pharmacokinetic and pharmacodynamic data. Following the Phase 2 data presentation, the company will host a virtual investor event to discuss the results.

Market Sentiment Analysis

POSITIVE FACTORS

  • Positive data expected from the Phase 2 trial for ESK-001.
  • Potential for ESK-001 to be a best-in-class TYK2 inhibitor.
  • Company advancing a pipeline of oral therapies using precision data analytics.

Full Press Release Details

– Late-breaking oral presentation to highlight efficacy and safety of ESK-001 in a Phase 2 clinical trial and open label extension (OLE) study in adults with moderate-to-severe plaque psoriasis (STRIDE) –
– Additional Phase 1 poster presentation to describe pharmacokinetic and pharmacodynamic characteristics of ESK-001 in healthy participants –
– The Company will host a virtual investor event following the Phase 2 data presentation –
SOUTH SAN FRANCISCO, Calif., March 04, 2024 (GLOBE NEWSWIRE) -- Alumis Inc., a clinical stage biopharmaceutical company developing oral therapies using a precision approach to transform the lives of patients with immune-mediated diseases, today announced two clinical data presentations at the American Academy of Dermatology Annual Meeting taking place March 8-12, 2024, in San Diego, CA.
Details regarding the presentations are as follows:
Title: Efficacy and Safety of ESK-001, a Highly Selective Oral TYK2 Inhibitor, in a Phase 2 Study in
Adults with Moderate-to-severe Plaque Psoriasis (STRIDE)
Session Title: S026 – Late-Breaking Research: Session 1
Date and Time: March 9, 10:20–10:30 a.m. PT
E-Poster Presentation
Title: Pharmacokinetic and Pharmacodynamic Characteristics of ESK-001, an Oral Allosteric TYK2 Inhibitor, in Phase 1 Healthy Volunteer Trials
Poster number: 53968
Alumis will also host a virtual investor event to review the ESK-001 Phase 2 clinical data being presented at AAD on March 9 at 5:00 p.m. PT. To access the live webcast, please register by visiting the Events page on the Alumis website.
Alumis is a clinical-stage biopharmaceutical company developing oral therapies using a precision approach to optimize outcomes and transform the lives of patients with immune-mediated diseases. Leveraging its precision data analytics and a multi-platform approach, Alumis is advancing a pipeline of oral therapies designed to address immune dysfunction. Alumis’ lead candidate ESK-001 is a highly selective and potentially best-in-class allosteric tyrosine kinase 2 (TYK2) inhibitor that is currently being evaluated for the treatment of patients with moderate to severe plaque psoriasis, systemic lupus erythematosus (SLE), and non-infectious uveitis. Alumis also has discovery efforts in undisclosed immune-mediated diseases and targets identified by its data analytics platform. Incubated by Foresite Labs and led by a team of experts with deep experience and proven track records in drug discovery, development and immunology, Alumis is developing transformative therapies that aim to reimagine the lives of people with immune-mediated diseases. For more information, please visit alumis.com.
Alumis Contact Information
Red House Communications

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Frequently Asked Questions

What is ESK-001 being studied for?

ESK-001 is evaluated for moderate to severe plaque psoriasis.

When will the Phase 2 data be presented?

The Phase 2 data presentation is on March 9, 2024, at 10:20 a.m. PT.

What other presentation will take place at the AAD meeting?

There will be a Phase 1 poster on ESK-001's characteristics.

How can I access the virtual investor event?

Register via the Events page on the Alumis website.

What is Alumis Inc. focused on?

Alumis focuses on developing oral therapies for immune-mediated diseases.

Last updated: Mar 4, 2024