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Allogene Therapeutics to Announce Interim Futility Analysis Data from its Pivotal Phase 2 ALPHA3 Trial with Cemacabtagene Ansegedleucel (Cema-Cel) in First-Line Consolidation LBCL on Monday, April 13, 2026

Key Takeaway: Allogene Therapeutics will announce the interim futility analysis data from its pivotal Phase 2 ALPHA3 trial involving cemacabtagene ansegedleucel (Cema-Cel) for first-line consolidation in large B-cell lymphoma. The conference call and webcast are scheduled for April 13, 2026, at 5:30 a.m. PT. This analysis is a significant step in evaluating the therapy's effectiveness.
Price reaction · baseline $2.91 (2026-04-09 close) · hit after-hours · 5 other ALLO headline(s) in the window, move may be shared
day 0 close
-6.5%
day 1
+5.2%
day 3 · peak
-25.4%

Market Sentiment Analysis

POSITIVE FACTORS

  • Allogene is advancing its pivotal Phase 2 ALPHA3 trial.
  • The interim futility analysis may provide valuable insights.
  • The company is pioneering allogeneic CAR T therapies.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+57%
120-day peak, hindsight
Typical move
5.6%
average across 5 past catalysts
Cash runway
~39 mo
Minimal dilution risk
Lead asset
ALLO-715
Phase 1 · Relapsed/Refractory Multiple Myeloma

Full Press Release Details

SOUTH SAN FRANCISCO, Calif., April 10, 2026 (GLOBE NEWSWIRE) -- Allogene Therapeutics, Inc. (Nasdaq: ALLO), a clinical-stage biotechnology company pioneering the development of allogeneic CAR T (AlloCAR T) products for cancer and autoimmune disease, today announced the Company will host a conference call and webcast to review the interim futility analysis from its pivotal, randomized Phase 2 ALPHA3 trial with cemacabtagene ansegedleucel (cema-cel) in first-line (1L) consolidation large B-cell lymphoma (LBCL) on Monday, April 13, 2026.
The live conference call and webcast will take place at 5:30 a.m. PT / 8:30 a.m. ET. Please use thislinkto register. The webcast will be made available on the Company's website atwww.allogene.comunder the Investors tab in the News and Events section.
About Allogene TherapeuticsAllogene Therapeutics, with headquarters in South San Francisco, is a clinical-stage biotechnology company pioneering the development of allogeneic chimeric antigen receptor T cell (AlloCAR T) products for cancer and autoimmune disease. Led by cell therapy veterans applying proven CAR T experience, Allogene is developing a pipeline of “off-the-shelf” CAR T cell product candidates with the goal of delivering readily available cell therapy on-demand, more reliably, and at greater scale to more patients. For more information, please visitwww.allogene.com, and follow Allogene Therapeutics on X and LinkedIn.

Allogene Media/Investor Contact:Christine CassianoEVP, Chief Corporate Affairs & Brand Strategy OfficerChristine.Cassiano@allogene.com

Frequently Asked Questions

What is the ALPHA3 trial about?

The ALPHA3 trial evaluates cemacabtagene ansegedleucel (Cema-Cel) for first-line consolidation in large B-cell lymphoma.

When will the interim analysis data be announced?

The interim futility analysis data will be announced on April 13, 2026.

How can I access the conference call?

You can register for the conference call and webcast through Allogene's website.

What is Allogene Therapeutics focused on?

Allogene Therapeutics focuses on developing allogeneic CAR T therapies for cancer and autoimmune diseases.

Last updated: Apr 10, 2026