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Rapid, profound and durable antiviral effects in treatment-naïve or currently-not-treated subjects with chronic hepatitis B virus infection that received 300 mg pevifoscorvir sodium monotherapy for 96 weeks

Key Takeaway: The study reports significant antiviral effects from 300 mg pevifoscorvir sodium monotherapy in treatment-naïve or currently untreated patients with chronic hepatitis B virus infection. The treatment demonstrated rapid and durable results over a 96-week period, indicating its potential as a viable therapeutic option for this patient population.
Price reaction · baseline $11.03 (2025-12-09T19:38:00.000Z) · hit during market hours · 2 other ALGS headline(s) in the window, move may be shared
day 0 close · peak
+0.5%

Market Sentiment Analysis

POSITIVE FACTORS

  • Demonstrated rapid antiviral effects in chronic HBV patients.
  • Treatment showed durability over a 96-week period.
  • Monotherapy with pevifoscorvir sodium is promising for treatment-naïve subjects.

BiopharmaWatch Analysis

From our catalyst data and publicly available data · not financial advice
Best trade, last catalyst
+153%
120-day peak, hindsight
Typical move
6.1%
average across 6 past catalysts
Cash runway
~3 mo
High dilution risk
Lead asset
ALG-055009
Phase 2 · NASH

Full Press Release Details

• About Overview Management Board of Directors
• Science Pipeline Posters & Presentations
• Patients Chronic HBV Infection MASH Clinical Trials Expanded Access Policy
• News & Media Press Releases Presentations & Events
• Investors Overview Stock Stock Quote & Chart Analyst Coverage News & Events News Releases Investor Calendar Financials SEC Filings Quarterly Results Governance Governance Highlights Committee Composition Resources Investor FAQs Email Alerts Contact IR
• Careers
• Overview
• Management
• Board of Directors
• Pipeline
• Posters & Presentations
• Chronic HBV Infection
• MASH
• Clinical Trials
• Expanded Access Policy
• Press Releases
• Presentations & Events
• Overview
• Stock Stock Quote & Chart Analyst Coverage
• News & Events News Releases Investor Calendar
• Financials SEC Filings Quarterly Results
• Governance Governance Highlights Committee Composition
• Resources Investor FAQs Email Alerts Contact IR
• Stock Quote & Chart
• Analyst Coverage
• News Releases
• Investor Calendar
• SEC Filings
• Quarterly Results
• Governance Highlights
• Committee Composition
• Investor FAQs
• Email Alerts
• Contact IR

Frequently Asked Questions

What is pevifoscorvir sodium?

Pevifoscorvir sodium is an antiviral medication used to treat chronic hepatitis B virus infection.

How long was the treatment duration in the study?

The treatment duration was 96 weeks.

Who were the subjects in the study?

The subjects included treatment-naïve or currently untreated patients with chronic HBV infection.

What were the results of the treatment?

The treatment showed rapid and durable antiviral effects in the patients.

Last updated: Dec 9, 2025