Full Press Release Details
Aditxt Subsidiary Pearsanta Completes the Acquisition
of Proprietary Adductomics Technology to Develop and Advance the Platform toward Clinical and Commercial Applications for Monitoring Early
Signs of Increased Cancer Risk
Acquisition is key to Pearsanta's mission
of addressing cancer through early detection and prevention
Pearsanta plans further validation and regulatory
submissions to support commercialization within its Richmond, Virginia CLIA/CAP-certified monitoring center and laboratories
MOUNTAIN VIEW, Calif., March 24, 2025 - (BUSINESS WIRE) -
Aditxt, Inc. (NASDAQ: ADTX) ("Aditxt" or the "Company"), a social innovation platform accelerating promising health
innovations, today announced that its subsidiary, Pearsanta, Inc. ("Pearsanta"), has acquired key patents related to adductomics-based
DNA damage detection, which it believes will further strengthen its position in the cancer prevention-focused diagnostic industry.
Pearsanta acquired the patents in exchange for the issuance of Pearsanta
Convertible Preferred Stock in a transaction valued at approximately $1 million. Over the next two to three years, Pearsanta will seek
to advance clinical validation, regulatory submissions, and commercialization efforts to integrate this technology into its diagnostic
The acquisition aligns with Pearsanta's mission to advance early
cancer detection and prevention that is globally accessible. Mitomic Technology, Pearsanta's proprietary platform, uses mitochondrial
DNA biomarkers designed for non-invasive cancer detection. With the addition of adductomics-based DNA damage analysis, Pearsanta is expanding
its capabilities to assess carcinogen exposure and genomic instability before permanent mutations occur, reinforcing its commitment to
proactive cancer risk assessment.
Enhancing Early Cancer Detection with Adductomics
The acquired patents cover proprietary advancements in DNA adduct detection
and analysis, providing the capability to assess genomic instability caused by environmental toxins and metabolic byproducts. DNA adducts-chemical
modifications to DNA nucleotides caused by carcinogens-are among the earliest detectable indicators of cancer risk.
Pearsanta intends to develop this platform into a comprehensive, panoramic
assessment tool for DNA adducts, utilizing urine, blood or solid tissue samples to provide actionable insights into DNA damage before
mutations occur. This approach has the potential to identify environmental or biological factors contributing to cancer risk, offering
earlier intervention strategies for individuals at elevated risk.
Advancing Toward Commercialization
Pearsanta is advancing a strategic development plan to bring adductomics-based
diagnostics to market, focusing on:
Over the next two to three years, Pearsanta aims to incorporate adductomics-based
screening into its expanding portfolio of precision oncology solutions, reinforcing its commitment to shifting cancer diagnostics from
late-stage detection to proactive prevention.
Pearsanta's Role in the Future of Cancer Prevention
Current cancer diagnostics predominantly detect tumors after they have
developed, leaving patients with limited treatment options that are often costly and less effective. Pearsanta's approach, strengthened
by the acquisition of adductomics technology, represents a new frontier in cancer prevention, potentially facilitating identification
of DNA damage at its earliest molecular stages-before irreversible mutations occur.
"We envision a world where cancer risk can be assessed before
symptoms appear, giving patients and physicians the opportunity to intervene when it matters most," said Chris Mitton, President
of Pearsanta. "We believe that Pearsanta is uniquely positioned to shift cancer care from reactive treatment to proactive prevention.
This advancement has the potential to redefine cancer care by enabling earlier risk assessment, allowing individuals to adjust lifestyle
factors, reduce exposure to carcinogens and adopt personalized prevention strategies. In underserved regions, where access to oncology
treatments remains limited, we believe that adductomics-based screening could provide a cost-effective tool for early cancer risk assessment,
empowering preventive measures when they are most effective."
Additionally, by detecting DNA damage before disease progression, this
technology has the potential to lower the overall economic burden of cancer, reducing the reliance on late-stage treatments and hospitalizations.
"Pearsanta's acquisition reflects Aditxt's commitment
to driving innovation with the potential of addressing some of the most pressing health challenges such as cancer," said Amro Albanna,
Co-Founder, Chairman, and CEO of Aditxt. "We believe that this technology has the potential to redefine how we assess and mitigate
cancer risk, which could reshape the future of early detection and prevention of cancer."
Pearsanta is at the forefront of precision health, focusing on early
cancer detection through advanced diagnostic technologies. Its proprietary Mitomic Technology Platform leverages the unique properties
of mitochondrial DNA to detect cancer and other diseases with high accuracy via non-invasive, blood-based liquid biopsy tests. Pearsanta's
asset portfolio also includes a range of other innovative diagnostic technologies, all aimed at transforming early disease detection and
monitoring, enabling more informed treatment decisions and ultimately improving patient outcomes. For more information, please visit www.pearsanta.com.
Aditxt, Inc. is a social innovation platform dedicated to accelerating
promising health innovations. Aditxt's ecosystem of research institutions, industry partners, and shareholders collaboratively drives
its mission to "Make Promising Innovations Possible Together." The innovation platform is the cornerstone of Aditxt's
strategy, where multiple disciplines drive disruptive growth and address significant societal challenges. Aditxt operates a unique model
that democratizes innovation, ensures every stakeholder's voice is heard and valued, and empowers collective progress.
Aditxt currently operates two programs focused on immune health and
precision health. The Company plans to introduce two additional programs dedicated to public health and women's health. For these,
Aditxt has entered into an Arrangement Agreement with Appili Therapeutics, Inc. ("Appili") (TSX: APLI; OTCPink: APLIF), which
focuses on infectious diseases, and a Merger Agreement with Evofem Biosciences, Inc. ("Evofem") (OTCQB: EVFM). Each program
will be designed to function autonomously while collectively advancing Aditxt's mission of discovering, developing and deploying
innovative health solutions to tackle some of the most urgent health challenges. The closing of each of the transactions with Appili and
Evofem is subject to several conditions, including but not limited to approval of the transactions by the respective target shareholders
and Aditxt raising sufficient capital to fund its obligations at closing. These obligations include cash payments of approximately $17
million for Appili and $17 million for Evofem, which includes approximately $15.2 million required to satisfy Evofem's senior secured
noteholder; should Aditxt fail to secure these funds, Evofem's senior secured noteholder is expected to seek to prevent the closing of
the merger with Evofem. On Dec. 23, 2024, Evofem announced the cancellation of its special stockholders meeting and the withdrawal of
the merger proposal with Aditxt from consideration by the stockholders. No assurance can be provided that all of the conditions to closing
will be obtained or satisfied or that either of the transactions will ultimately close.
Forward-Looking Statements
Certain statements in this press release constitute "forward-looking
statements" within the meaning of federal securities laws. Forward-looking statements include statements regarding the Company's
intentions, beliefs, projections, outlook, analyses, or current expectations concerning, among other things, the Company's ongoing
and planned product and business development; the Company's ability to finance and execute its strategic M&A initiatives; the
Company's ability to obtain the necessary funding and partner to commence clinical trials; the Company's intellectual property
position; the Company's ability to develop commercial functions; expectations regarding product launch and revenue; the Company's
results of operations, cash needs, spending, financial condition, liquidity, prospects, growth, and strategies; the Company's ability
to raise additional capital; expected usage of the Company's ELOC and ATM facilities; the industry in which the Company operates;
and the trends that may affect the industry or the Company. Forward-looking statements are not guarantees of future performance, and actual
results may differ materially from those indicated by these forward-looking statements as a result of various important factors, as well
as market and other conditions and those risks more fully discussed in the section titled "Risk Factors" in Aditxt's most
recent Annual Report on Form 10-K, as well as discussions of potential risks, uncertainties, and other important factors in the Company's
other filings with the Securities and Exchange Commission. All such statements speak only as of the date made, and the Company undertakes
no obligation to update or revise publicly any forward-looking statements, whether as a result of new information, future events or otherwise,
except as required by law.
Corporate Communications
Jeff Ramson, PCG Advisory, Inc.