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Acrivon Therapeutics Appoints Seasoned Industry Executive Ivana Magov evi -Liebisch, Ph.D., J.D., to Board of Directors

Key Takeaway: Acrivon Therapeutics has appointed Ivana Magov evi-Liebisch, Ph.D., J.D., to its Board of Directors. With over 25 years of industry experience, she has led various strategic initiatives in biopharmaceutical companies, including successful partnerships and commercialization efforts. Acrivon is currently developing precision oncology medicines using its proprietary platform, with a focus on its lead candidate ACR-368, which is advancing into clinical trials. The company aims to improve patient outcomes through innovative therapy strategies.

Market Sentiment Analysis

POSITIVE FACTORS

  • Appointment of Ivana Magov evi-Liebisch is expected to enhance Acrivon's strategic capabilities.
  • Dr. Magov evi-Liebisch brings over 25 years of industry experience that can benefit Acrivon's pipeline.
  • Acrivon is advancing clinical-stage programs with promising drug candidates like ACR-368.

Full Press Release Details

Acrivon Therapeutics Appoints Seasoned Industry Executive Ivana Magov evi -Liebisch, Ph.D.,
J.D., to Board of Directors
WATERTOWN, Massachusetts, February 8, 2024 Acrivon Therapeutics, Inc.
( Acrivon or Acrivon Therapeutics ) (Nasdaq: ACRV), a clinical stage biopharmaceutical company developing precision oncology medicines that it matches to patients whose tumors are predicted to be sensitive to each specific
medicine by utilizing its proprietary proteomics-based patient responder identification platform, Acrivon Predictive Precision Proteomics or AP3, today announced the appointment of Ivana Magov evi -Liebisch, Ph.D., J.D., to its board of
We are excited to welcome Ivana to our board of directors, said Peter Blume-Jensen, M.D., Ph.D., chief executive officer,
president, and founder of Acrivon Therapeutics. She brings more than 25 years of experience spanning global business and R&D operations, including leading partnering activities, commercialization, research and development, as well as
counseling on regulatory, legal and IP strategies. Her diverse and substantial expertise will benefit us as we advance our pipeline of novel compounds.
Dr. Magov evi -Liebisch is the president and chief executive officer at Vigil Neuroscience, Inc., where she led the in-licensing deal that secured the company s anchor assets from Amgen. Under her strong leadership, Vigil has evolved from inception through IPO, to an organization with two clinical-stage development programs.
Prior to Vigil, Dr. Magov evi -Liebisch was the executive vice president and chief business officer at Ipsen where she was responsible for growing the pipeline through strategic transactions. Before joining Ipsen,
Dr. Magov evi -Liebisch served as senior vice president and head of global business development for the specialty drug business at Teva Pharmaceutical Industries Ltd. where she executed multiple transactions across different
therapeutic areas and modalities. Prior to Teva, Dr. Magov evi -Liebisch held multiple pivotal roles at Dyax including executive vice president, chief operating officer, chief business officer, and general counsel. During her time,
she established the commercial infrastructure for the company s first approved drug with high-touch patient services, developed and executed IP strategy for a successful licensing program as well as equity financings, revenue monetization,
corporate partnerships, and licensing agreements. Dr. Magov evi -Liebisch has served on the Board of Directors of Absci, Aeglea Therapeutics and Applied Genetic Technologies Corporation. She holds a Ph.D. in genetics from Harvard
University and a J.D. in high technology law from Suffolk University Law School. She graduated from Wheaton College with a B.A. (summa cum laude) in biology and chemistry.
Dr. Magov evi -Liebisch added, I am inspired by the pursuit of innovation, and I believe that Acrivon s AP3 platform is poised to
make a major impact in the field of precision medicine. I look forward to working with Peter, the board, and the executive team to develop multiple promising drug candidates to improve patient lives.
About Acrivon Therapeutics
Acrivon is a clinical stage biopharmaceutical company developing precision oncology medicines that it matches to patients whose tumors are predicted to be
sensitive to each specific medicine by utilizing Acrivon s proprietary proteomics-based patient responder identification platform, Acrivon Predictive Precision Proteomics, or AP3. The AP3 platform is engineered to measure compound-specific
effects on the entire tumor cell protein signaling network and drug-induced resistance mechanisms in an unbiased manner. These distinctive capabilities enable AP3 s direct application for drug design optimization for monotherapy activity, the
identification of rational drug combinations, and the creation of drug-specific proprietary OncoSignature companion diagnostics that are used to identify the patients most likely to benefit from Acrivon s drug candidates. Acrivon is currently
advancing its lead candidate, ACR-368, a selective small molecule inhibitor targeting CHK1 and CHK2 in a potentially registrational Phase 2 trial across multiple tumor types. The company has received Fast
Track designation from the Food and Drug Administration, or FDA, for the investigation of ACR-368 as monotherapy based on OncoSignature-predicted sensitivity in patients with platinum-resistant ovarian or
endometrial cancer. Acrivon s ACR-368 OncoSignature test, which has not yet obtained regulatory approval, has been extensively evaluated in preclinical studies, including in two separate, blinded,
prospectively-designed studies on pretreatment tumor biopsies collected from past third-party Phase 2 trials in patients with ovarian cancer treated with ACR-368. The FDA has granted Breakthrough Device
designation for the ACR-368 OncoSignature assay for the identification of ovarian cancer patients who may benefit from ACR-368 treatment. In addition to ACR-368, Acrivon is also leveraging its proprietary AP3 precision medicine platform for developing its co-crystallography-driven, internally-discovered preclinical stage
pipeline programs, including its development candidate, ACR-2316, a selective, dual WEE1/PKMYT1 inhibitor, and an undisclosed cell cycle program.
Forward-Looking Statements
This press release includes
certain disclosures that contain forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995 about us and our industry that involve substantial risks and uncertainties. All statements other than
statements of historical facts contained in this press release, including statements regarding our future results of operations or financial condition, business strategy and plans and objectives of management for future operations, are
forward-looking statements. In some cases, you can identify forward-looking statements because they contain words such as anticipate, believe, contemplate, continue, could,
estimate, expect, intend, may, plan, potential, predict, project, should, target, will, or would or the
negative of these words or other similar terms or expressions. Forward-looking statements are based on Acrivon s current expectations and are subject to inherent uncertainties, risks and assumptions that are difficult to predict. Factors that
could cause actual results to differ include, but are not limited to, risks and uncertainties that are described more fully in the section titled Risk Factors in our reports filed with the Securities and Exchange Commission.
Forward-looking statements contained in this press release are made as of this date, and Acrivon undertakes no duty to update such information except as required under applicable law.
Investor and Media Contacts:
Adam D. Levy, Ph.D.,

Frequently Asked Questions

Who has been appointed to Acrivon's Board of Directors?

Ivana Magov evi -Liebisch, Ph.D., J.D., has joined Acrivon's Board.

What is Acrivon's primary focus in drug development?

Acrivon specializes in precision oncology medicines tailored to patient tumor sensitivity.

What platform does Acrivon use for patient identification?

Acrivon utilizes the AP3 platform for proteomics-based patient responder identification.

What is ACR-368's significance in Acrivon's pipeline?

ACR-368 targets CHK1 and CHK2 and is in a Phase 2 trial for various tumors.

What regulatory designations has ACR-368 received?

ACR-368 has received Fast Track and Breakthrough Device designations from the FDA.

Last updated: Feb 8, 2024