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AbbVie Reports First-Quarter 2025 Financial Results Reports First-Quarter Diluted EPS of $0.72 on a GAAP Basis, a Decrease of 6.5 Percent; Adjusted Diluted EPS of $2.46, an Increase of 6.5 Percent;...

Key Takeaway: AbbVie reported better-than-expected financial results for the first quarter of 2025, with adjusted diluted EPS increasing 6.5% to $2.46, despite a GAAP EPS decline. The company raised its full-year adjusted EPS guidance to between $12.09 and $12.29, indicating confidence in ongoing business fundamentals and pipeline advancements. However, it faced challenges with a 6.5% drop in GAAP EPS and potential impacts from trade policies and acquired expenses. Overall, AbbVie's outlook remains strong, bolstered by robust revenue growth in its immunology and oncology segments.

Market Sentiment Analysis

POSITIVE FACTORS

  • AbbVie's first-quarter results exceeded expectations.
  • The company raised its adjusted diluted EPS guidance for the full year 2025.
  • Strong performance in immunology and certain oncological products.

CONCERNS & RISKS

  • GAAP diluted EPS showed a decline of 6.5 percent.
  • The company's full-year guidance includes an unfavorable impact of $0.13 per share from acquired IPR&D and milestones.

Full Press Release Details

NORTH CHICAGO, Ill. , April 25, 2025 /PRNewswire/ -- AbbVie (NYSE: ABBV ) announced financial results for the first quarter ended March 31, 2025 .
"AbbVie's first-quarter results were well ahead of our expectations and reflect an excellent start to the year," said Robert A. Michael , chief executive officer, AbbVie. "The fundamentals of our business are strong and we continue to bolster our outlook with pipeline advancements and strategic investments. Based on the progress we are making, AbbVie is well positioned for the long term."
First -Quarter Results
Full-Year 2025 Outlook
AbbVie is raising its adjusted diluted EPS guidance for the full year 2025 from $11.99 - $12.19 to $12.09 - $12.29 , which includes an unfavorable impact of $0.13 per share related to acquired IPR&D and milestones expense incurred year-to-date through the first quarter 2025. The company's 2025 adjusted diluted EPS guidance excludes any impact from acquired IPR&D and milestones that may be incurred beyond the first quarter of 2025, as both cannot be reliably forecasted. This guidance does not reflect the acquired IPR&D and milestones impact related to AbbVie and Gubra's licensing agreement to develop GUB014295, as that transaction closed after the first quarter of 2025. Additionally, this guidance is based on the existing trade environment and does not reflect any trade policy shifts, including pharmaceutical sector tariffs, that could impact AbbVie's business.
AbbVie's mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas: immunology, neuroscience, oncology, and eye care - and products and services across our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on X (formerly Twitter), Facebook , Instagram , YouTube or LinkedIn .
Conference Call
AbbVie will host an investor conference call today at 8:00 a.m. Central Time to discuss our first-quarter performance. The call will be webcast through AbbVie's Investor Relations website at investors.abbvie.com . An archived edition of the call will be available after 11:00 a.m. Central Time .
Non-GAAP Financial Results
Financial results for 2025 and 2024 are presented on both a reported and a non-GAAP basis. Reported results were prepared in accordance with GAAP and include all revenue and expenses recognized during the period. Non-GAAP results adjust for certain non-cash items and for factors that are unusual or unpredictable, and exclude those costs, expenses, and other specified items presented in the reconciliation tables later in this release. AbbVie's management believes non-GAAP financial measures provide useful information to investors regarding AbbVie's results of operations and assist management, analysts, and investors in evaluating the performance of the business. Non-GAAP financial measures should be considered in addition to, and not as a substitute for, measures of financial performance prepared in accordance with GAAP.
Forward-Looking Statements
Some statements in this news release are, or may be considered, forward-looking statements for purposes of the Private Securities Litigation Reform Act of 1995. The words "believe," "expect," "anticipate," "project" and similar expressions and uses of future or conditional verbs, generally identify forward-looking statements. AbbVie cautions that these forward-looking statements are subject to risks and uncertainties that may cause actual results to differ materially from those expressed or implied in the forward-looking statements. Such risks and uncertainties include, but are not limited to, challenges to intellectual property, competition from other products, difficulties inherent in the research and development process, adverse litigation or government action, changes to laws and regulations applicable to our industry, the impact of global macroeconomic factors, such as economic downturns or uncertainty, international conflict, trade disputes and tariffs, and other uncertainties and risks associated with global business operations. Additional information about the economic, competitive, governmental, technological and other factors that may affect AbbVie's operations is set forth in Item 1A, "Risk Factors," of AbbVie's 2024 Annual Report on Form 10-K, which has been filed with the Securities and Exchange Commission, as updated by its Quarterly Reports on Form 10-Q and in other documents that AbbVie subsequently files with the Securities and Exchange Commission that update, supplement or supersede such information. AbbVie undertakes no obligation, and specifically declines, to release publicly any revisions to forward-looking statements as a result of subsequent events or developments, except as required by law.
Media: Investors:
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AbbVie Inc. Key Product Revenues Quarter Ended March 31, 2025 (Unaudited)
% Change vs. 1Q24
Net Revenues (in millions) Reported Operational a
U.S. Int'l. Total U.S. Int'l. Total Int'l. Total
NET REVENUES $9,979 $3,364 $13,343 10.4 % 2.9 % 8.4 % 8.3 % 9.8 %
Immunology 4,883 1,381 6,264 17.6 13.4 16.6 20.1 18.1
Skyrizi 2,919 506 3,425 76.2 43.9 70.5 52.3 72.0
Rinvoq 1,220 498 1,718 68.3 35.3 57.2 42.8 59.7
Humira 744 377 1,121 (58.0) (24.4) (50.6) (19.5) (49.5)
Neuroscience 1,972 310 2,282 15.0 24.0 16.1 31.0 17.0
Vraylar 763 2 765 10.3 13.1 10.3 20.2 10.3
Botox Therapeutic 723 143 866 18.2 4.8 15.8 11.4 17.0
Ubrelvy 233 7 240 17.6 23.3 17.8 29.3 18.0
Qulipta 172 21 193 34.2 >100.0 47.6 >100.0 48.3
Vyalev 6 57 63 n/m >100.0 >100.0 >100.0 >100.0
Duodopa 20 76 96 (19.4) (16.0) (16.7) (11.7) (13.3)
Other Neuroscience 55 4 59 (9.5) (1.0) (8.9) 6.5 (8.4)
Oncology 1,027 606 1,633 6.0 5.4 5.8 10.0 7.5
Imbruvica b 529 209 738 (13.3) (8.2) (11.9) (8.2) (11.9)
Venclexta 312 353 665 11.0 6.0 8.3 13.4 12.3
Elahere 165 14 179 >100.0 n/m >100.0 n/m >100.0
Epkinly c 21 30 51 66.7 >100.0 89.8 >100.0 94.8
Aesthetics 640 462 1,102 (17.4) (2.4) (11.7) 1.6 (10.2)
Botox Cosmetic 295 261 556 (24.3) 6.9 (12.3) 11.1 (10.7)
Juvederm Collection 75 156 231 (29.0) (18.5) (22.2) (15.0) (20.0)
Other Aesthetics 270 45 315 (3.5) 18.1 (0.9) 23.2 (0.3)
Eye Care 221 285 506 (2.6) (8.0) (5.7) (2.0) (2.2)
Ozurdex 30 93 123 (12.1) (3.8) (6.0) 1.1 (2.4)
Lumigan/Ganfort 48 58 106 69.2 (6.8) 17.0 (0.5) 21.4
Alphagan/Combigan 26 34 60 68.5 (21.4) 1.9 (15.4) 6.3
Other Eye Care 117 100 217 (21.4) (7.1) (15.4) (0.2) (12.5)
Other Key Products 636 173 809 (7.2) (19.4) (10.1) (14.8) (9.0)
Mavyret 142 164 306 (0.7) (20.4) (12.3) (15.8) (9.6)
Creon 355 355 24.6 n/m 24.6 n/m 24.6
Linzess/Constella 139 9 148 (46.1) 3.1 (44.4) 9.3 (44.2)
a "Operational" comparisons are presented at constant currency rates that reflect comparative local currency net revenues at the prior year's foreign exchange rates.
b Reflects profit sharing for Imbruvica international revenues.
c Epkinly U.S. revenues reflect profit sharing. International revenues reflect product revenues as well as profit sharing from certain international territories.
n/m = not meaningful
AbbVie Inc. Consolidated Statements of Earnings (Unaudited)
(in millions, except per share data) First Quarter Ended March 31
2025 2024
Net revenues $ 13,343 $ 12,310
Cost of products sold 4,002 4,094
Selling, general and administrative 3,293 3,315
Research and development 2,067 1,939
Acquired IPR&D and milestones 248 164
Total operating costs and expenses 9,610 9,512
Operating earnings 3,733 2,798
Interest expense, net 627 453
Net foreign exchange loss 4 4
Other expense, net 1,441 586
Earnings before income tax expense 1,661 1,755
Income tax expense 372 383
Net earnings 1,289 1,372
Net earnings attributable to noncontrolling interest 3 3
Net earnings attributable to AbbVie Inc. $ 1,286 $ 1,369
Diluted earnings per share attributable to AbbVie Inc. $ 0.72 $ 0.77
Adjusted diluted earnings per share a $ 2.46 $ 2.31
Weighted-average diluted shares outstanding 1,772 1,773
AbbVie Inc. Reconciliation of GAAP Reported to Non-GAAP Adjusted Information (Unaudited)
1. Specified items impacted results as follows:
Quarter Ended March 31, 2025
(in millions, except per share data) Earnings Diluted
Pre-tax After-tax a EPS
As reported (GAAP) $ 1,661 $ 1,286 $ 0.72
Adjusted for specified items:
Intangible asset amortization 1,858 1,574 0.89
Change in fair value of contingent consideration 1,518 1,477 0.83
Other 62 33 0.02
As adjusted (non-GAAP) $ 5,099 $ 4,370 $ 2.46
a Represents net earnings attributable to AbbVie Inc. Specified items reflect the impact of applicable statutory tax rates.
Reported GAAP earnings and adjusted non-GAAP earnings for the three months ended March 31, 2025 included acquired IPR&D and milestones expense of $248 million on a pre-tax and $238 million on an after-tax basis, representing an unfavorable impact of $0.13 to both diluted EPS and adjusted diluted EPS.
2. The impact of the specified items by line item was as follows:
Quarter Ended March 31, 2025
(in millions) Cost of products sold SG&A R&D Other expense, net
As reported (GAAP) $ 4,002 $ 3,293 $ 2,067 $ 1,441
Adjusted for specified items:
Intangible asset amortization (1,858)
Change in fair value of contingent consideration (1,518)
Other (28) (13) (16) (5)
As adjusted (non-GAAP) $ 2,116 $ 3,280 $ 2,051 $ (82)
3. The adjusted tax rate for the first quarter of 2025 was 14.2 percent, as detailed below:
Quarter Ended March 31, 2025
(dollars in millions) Pre-tax earnings Income taxes Tax rate
As reported (GAAP) $ 1,661 $ 372 22.4 %
Specified items 3,438 354 10.3 %
As adjusted (non-GAAP) $ 5,099 $ 726 14.2 %
AbbVie Inc. Reconciliation of GAAP Reported to Non-GAAP Adjusted Information (Unaudited)
1. Specified items impacted results as follows:
Quarter Ended March 31, 2024
(in millions, except per share data) Earnings Diluted
Pre-tax After-tax a EPS
As reported (GAAP) $ 1,755 $ 1,369 $ 0.77
Adjusted for specified items:
Intangible asset amortization 1,891 1,603 0.90
Acquisition and integration costs 511 486 0.27
Change in fair value of contingent consideration 660 643 0.36
Other 21 19 0.01
As adjusted (non-GAAP) $ 4,838 $ 4,120 $ 2.31
a Represents net earnings attributable to AbbVie Inc. Specified items reflect the impact of applicable statutory tax rates.
Acquisition and integration costs primarily reflect costs related to the ImmunoGen acquisition.
Reported GAAP earnings and adjusted non-GAAP earnings for the three months ended March 31, 2024 included acquired IPR&D and milestones expense of $164 million on a pre-tax and $138 million on an after-tax basis, representing an unfavorable impact of $0.08 to both diluted EPS and adjusted diluted EPS.
2. The impact of the specified items by line item was as follows:
Quarter Ended March 31, 2024
(in millions) Cost of products sold SG&A R&D Interest expense, net Other expense, net
As reported (GAAP) $ 4,094 $ 3,315 $ 1,939 $ 453 $ 586
Adjusted for specified items:
Intangible asset amortization (1,891)
Acquisition and integration costs (79) (280) (128) (24)
Change in fair value of contingent consideration (660)
Other (16) (3) (2)
As adjusted (non-GAAP) $ 2,108 $ 3,032 $ 1,811 $ 429 $ (76)
3. The adjusted tax rate for the first quarter of 2024 was 14.8 percent, as detailed below:
Quarter Ended March 31, 2024
(dollars in millions) Pre-tax earnings Income taxes Tax rate
As reported (GAAP) $ 1,755 $ 383 21.8 %
Specified items 3,083 332 10.8 %
As adjusted (non-GAAP) $ 4,838 $ 715 14.8 %

21 %

Frequently Asked Questions

What was AbbVie’s first-quarter net revenue for 2025?

AbbVie reported a net revenue of $13.343 billion for the first quarter of 2025.

What is AbbVie's adjusted EPS guidance for 2025?

AbbVie has raised its adjusted EPS guidance to a range of $12.09 to $12.29 for 2025.

Who is AbbVie’s CEO?

Robert A. Michael is the Chief Executive Officer of AbbVie.

How did AbbVie perform compared to expectations?

AbbVie’s first-quarter results exceeded expectations, indicating a strong business start.

When will AbbVie hold its investor conference call?

AbbVie will host an investor conference call today at 8:00 a.m. Central Time.

Last updated: Apr 25, 2025