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Specialist biotech fund · SEC 13F

TCG Crossover Management 13F Holdings (Q2 2026)

According to its SEC 13F filed on Aug 14, 2026, TCG Crossover Management reported 54 long positions worth $4.16B as of Jun 30, 2026. ABVX is 19.2% of the portfolio and the top 10 holdings are 57%. Against Q1 2026 it opened 12 new positions, added to 2, trimmed 9 and exited 7. 15 holdings have a dated FDA decision or data readout in the next 90 days, and 17 more expect one in a stated window such as "H2 2026".

Data as of Jun 30, 2026SEC 13F filed Aug 14, 2026Next filing (Q3 2026) due Nov 16, 2026Value as filed; options at underlying sharesLong positions only
Market Value$ 4.16 B13F value, as filed
QoQ Changes19.03 %13F value vs the previous quarter
Holdings54 54 stocks · 0 option positions
PeriodQ2 202613F reporting quarter
Holdings in Top 20 % top 10: 57% of the portfolio
Activity vs Q1 202612 new2 added · 9 trimmed · 7 exits
Catalysts ahead15dated in 90 days · +17 in a stated window

Catalysts ahead in this portfolio

Dated FDA decisions and data readouts for its holdings in the next 90 days, with our probability of approval

Nov 5, 2026MIRMPhase 2b data presentation: VolixibatPoA 35%
Nov 5, 2026CATXPhase 1/2a data readout: [212Pb]Bamzireotide Navoxetan (VMT-α-NET)PoA 22%

13 more with a subscription

What changed vs Q1 2026

ZLABZai Lab Limited$117M
AURAAura Biosciences$68M

Full lists with a subscription

Portfolio over time

13F value by quarter, Q4 2021 to Q2 2026

Q4 2021: $214MQ2 2026: $4.16B

By company stage (share of value)

Clinical 83%Commercial 11%Other 6%

Holdings

Every position in the 13F, with the change since the fund's previous filing, how many of the 45 specialist funds also own it, and its next FDA catalyst. Option positions are labelled CALL or PUT.

Showing 6 Stocks Out Of 54. Click On The Tickers For More Details
Stock Company Name Shares Held Market Value % of Portfolio QoQ Change Position Change Also Held By Stage Next Catalyst
FBRX
FBRX
FORTE BIOSCIENCES INC
920.00 K
19.55 M
0.5
New
Clinical
None in 90 days
RACC
RACC
RESEARCH ALLIANCE CORP CL A
500.00 K
5.35 M
0.1
New
—
None in 90 days
TRAX
TRAX
FIRST TRACKS BIOTHERAPEUTICS
2.90 M
58.25 M
1.4
New
—
Nov 30, 2026
Phase 1b data presentation
SLN
SLN
SILENCE THERAPEUTICS PLC
3.03 M
33.31 M
0.8
Unchanged
Clinical
Dec 12, 2026
Phase 2 data readout
MBX
MBX
MBX BIOSCIENCES INC
650.00 K
35.88 M
0.9
Unchanged
Clinical
Expected 2026
Phase 2a data readout
XNCR
XNCR
XENCOR INC
2.45 M
39.48 M
0.9
Unchanged
Clinical
Expected by end of 2026
Phase 2b data readout

Top 20 Holdings

Size = share of the portfolio. Option positions show CALL or PUT.

Who else owns these stocks?

All Stock Holdings ranks every biotech stock by how many of the 45 specialist funds own it, and whether that number rose or fell this quarter. Click "of 45 funds" on any row above, or open the full view.

Open All Stock Holdings ›

Questions about TCG Crossover Management's 13F

What does TCG Crossover Management own?

54 stocks worth $4.16B at Jun 30, 2026, as reported in its 13F, led by ABVX (19.2% of the portfolio). The full list is in the Holdings table above.

What did it buy and sell last quarter?

Against Q1 2026: 12 new positions, 2 increases, 9 reductions and 7 full exits, from its 13F filings.

How current is this data?

13F filings are due 45 days after each quarter ends, so they show positions at quarter end, not today. The next filing (Q3 2026) is due Nov 16, 2026.

Why are some positions labelled CALL or PUT?

Those are option positions (calls and puts). The 13F reports them as the shares underlying the option, with no strike or expiry, so they are listed apart from share positions.

Source: SEC EDGAR Form 13F-HR filed by TCG Crossover Management, LLC, accession 0001214659-26-010290, filed Aug 14, 2026. Values as filed; option positions are shown at the value of the underlying shares and labelled CALL or PUT.