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Philadelphia Chromosome Positive Acute Lymphocytic Leukemia: one US-listed biotech with a clinical-stage programme

OncologyUncontestedData as of 2026-09-04

Competitors1in the clinic
Median market cap$1.6Buniverse median $1.20B
Allocated capital$180M$1.6B competing
Phase 3 or filed10 mid, 0 early
Pure plays0this indication only
Capital rank259/299crowding rank 261

Philadelphia Chromosome Positive Acute Lymphocytic Leukemia is uncontested. Ascentage Pharma Group International Unsponsored (AAPG) is the only US-listed developer in the $100M to $20B band running a clinical programme here, with olverembatinib in phase 3.

There is no public comparable to price it against. AAPG spreads its $1.6B market cap across 9 indications, so $180M of it is allocated here.

The one programme here is in late-stage development, but it carries no dated catalyst in the next 12 months.

$180M of allocated capital sits in Philadelphia Chromosome Positive Acute Lymphocytic Leukemia, ranking it 259th of 299 indications by the money committed to it.

Companies developing drugs for Philadelphia Chromosome Positive Acute Lymphocytic Leukemia 1

TickerCompanyLead assetPhaseTrialsMarket capPure playIndicationsNext catalyst
AAPGAscentage Pharma Group International UnsponsoredolverembatinibPhase 32$1.6BNo9No dated event

Sorted by phase, then by market capitalisation. Ticker links open the company profile.

Why Philadelphia Chromosome Positive Acute Lymphocytic Leukemia counts as uncontested

Uncontested. One US-listed developer in the size band is running a clinical programme here, so there is no public comparable to price it against.

The map splits indications on two folds: six or more competitors counts as crowded, and a median company above $1.20B counts as richly priced. Philadelphia Chromosome Positive Acute Lymphocytic Leukemia has one competitor and a median of $1.6B.

Oncology

Oncology holds $187B of the map's capital, 27.8% of the total, spread across 119 indications and 103 companies. 34 of those indications have more than one company competing.

See every Oncology indication on the map

Related indications in Oncology

Chronic Myeloid Leukemia1 company · $180M · median $1.6BUncontestedLiposarcoma1 company · $180M · median $1.6BUncontestedLeukemia1 company · $176M · median $176MUncontestedAdvanced Hepatocellular Carcinoma1 company · $175M · median $175MUncontestedMetastatic Lung Cancer1 company · $162M · median $486MUncontestedRefractory/ Relapsed Non-Hodgkin Lymphoma1 company · $203M · median $610MUncontestedRelapsed and Refractory Multiple Myeloma1 company · $156M · median $156MUncontestedT-Cell Lymphoblastic Leukemia/Lymphoma2 companies · $149M · median $374MOrphan corner

Philadelphia Chromosome Positive Acute Lymphocytic Leukemia pipeline questions

Which biotech companies are developing drugs for Philadelphia Chromosome Positive Acute Lymphocytic Leukemia?

Ascentage Pharma Group International Unsponsored (AAPG, olverembatinib, Phase 3). Those are the 1 US-listed developer in the $100M to $20B market cap band with a clinical-stage programme in Philadelphia Chromosome Positive Acute Lymphocytic Leukemia.

How advanced is the Philadelphia Chromosome Positive Acute Lymphocytic Leukemia pipeline?

Of the 1 clinical-stage programme in Philadelphia Chromosome Positive Acute Lymphocytic Leukemia, 1 is in Phase 3 or filed, 0 are in mid-stage development and 0 are in early-stage development.

Is anyone else developing a drug for Philadelphia Chromosome Positive Acute Lymphocytic Leukemia?

No. AAPG is the only US-listed company in the $100M to $20B market cap band with a clinical-stage programme in Philadelphia Chromosome Positive Acute Lymphocytic Leukemia, which is why the indication is classified as uncontested.

How this page is built

  • Universe is US-listed drug developers with a $100M to $20B market capitalisation, identified by SEC SIC code 2833, 2834 or 2836 or by a pharmaceutical or biotechnology industry classification, less a reviewed exclusion list of contract research organisations, device and diagnostics makers and diversified generics manufacturers.
  • An asset attributed to three or more different companies is treated as shared standard of care rather than any one company’s programme and excluded. Pembrolizumab alone appears under 21 tickers in raw trial data.
  • A programme counts only where at least one industry-sponsored trial supports it, so investigator-initiated academic studies of third-party drugs are excluded.

Allocated capital divides each company’s market capitalisation evenly across the indications it is running clinical programmes in, so every dollar of the universe is counted exactly once. Total market capitalisation competing counts a company in each of its indications and therefore sums to more than the universe.

Third-party market size estimates are not used anywhere on this page. Approved incumbents are excluded from competitor counts, and companies above $20B are outside the universe by construction.

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