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Inflammatory Bowel Disease: one US-listed biotech with a clinical-stage programme

Immunology & InflammationUncontestedData as of 2026-09-04

Competitors1in the clinic
Median market cap$3.0Buniverse median $1.20B
Allocated capital$609M$3.0B competing
Phase 3 or filed01 mid, 0 early
Pure plays0this indication only
Capital rank191/299crowding rank 201

Inflammatory Bowel Disease is uncontested. Disc Medicine (IRON) is the only US-listed developer in the $100M to $20B band running a clinical programme here, with DISC-0974 in phase 2.

There is no public comparable to price it against. IRON spreads its $3.0B market cap across 5 indications, so $609M of it is allocated here.

Nothing here has reached Phase 3: 1 programme in mid stage and 0 in early stage, so the field is still several years from a first approval.

$609M of allocated capital sits in Inflammatory Bowel Disease, ranking it 191st of 299 indications by the money committed to it.

Companies developing drugs for Inflammatory Bowel Disease 1

TickerCompanyLead assetPhaseTrialsMarket capPure playIndicationsNext catalyst
IRONDisc MedicineDISC-0974Phase 21$3.0BNo5 9 Sep 2026

Sorted by phase, then by market capitalisation. Ticker links open the company profile.

Why Inflammatory Bowel Disease counts as uncontested

Uncontested. One US-listed developer in the size band is running a clinical programme here, so there is no public comparable to price it against.

The map splits indications on two folds: six or more competitors counts as crowded, and a median company above $1.20B counts as richly priced. Inflammatory Bowel Disease has one competitor and a median of $3.0B.

Immunology & Inflammation

Immunology & Inflammation holds $139B of the map's capital, 20.7% of the total, spread across 51 indications and 82 companies. 23 of those indications have more than one company competing.

See every Immunology & Inflammation indication on the map

Related indications in Immunology & Inflammation

Lupus Nephritis5 companies · $589M · median $516MOrphan cornerSystemic Sclerosis4 companies · $582M · median $540MOrphan cornerPsoriatic Arthritis1 company · $646M · median $1.3BUncontestedXerostomia1 company · $671M · median $1.3BUncontestedChronic Granulomatous Disease1 company · $673M · median $673MUncontestedAcne1 company · $673M · median $673MUncontestedIgG4 Related Disease1 company · $536M · median $2.1BUncontestedComplement 3 Glomerulopathy1 company · $461M · median $1.4BUncontested

Inflammatory Bowel Disease pipeline questions

Which biotech companies are developing drugs for Inflammatory Bowel Disease?

Disc Medicine (IRON, DISC-0974, Phase 2). Those are the 1 US-listed developer in the $100M to $20B market cap band with a clinical-stage programme in Inflammatory Bowel Disease.

How advanced is the Inflammatory Bowel Disease pipeline?

Of the 1 clinical-stage programme in Inflammatory Bowel Disease, 0 are in Phase 3 or filed, 1 is in mid-stage development and 0 are in early-stage development.

Is anyone else developing a drug for Inflammatory Bowel Disease?

No. IRON is the only US-listed company in the $100M to $20B market cap band with a clinical-stage programme in Inflammatory Bowel Disease, which is why the indication is classified as uncontested.

When is the next Inflammatory Bowel Disease catalyst?

The next dated catalyst in Inflammatory Bowel Disease is IRON on 9 Sep 2026. 1 dated event across the field fall in the next 12 months.

How this page is built

  • Universe is US-listed drug developers with a $100M to $20B market capitalisation, identified by SEC SIC code 2833, 2834 or 2836 or by a pharmaceutical or biotechnology industry classification, less a reviewed exclusion list of contract research organisations, device and diagnostics makers and diversified generics manufacturers.
  • An asset attributed to three or more different companies is treated as shared standard of care rather than any one company’s programme and excluded. Pembrolizumab alone appears under 21 tickers in raw trial data.
  • A programme counts only where at least one industry-sponsored trial supports it, so investigator-initiated academic studies of third-party drugs are excluded.

Allocated capital divides each company’s market capitalisation evenly across the indications it is running clinical programmes in, so every dollar of the universe is counted exactly once. Total market capitalisation competing counts a company in each of its indications and therefore sums to more than the universe.

Third-party market size estimates are not used anywhere on this page. Approved incumbents are excluded from competitor counts, and companies above $20B are outside the universe by construction.

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