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MTX-001

Phase 2

Venous Stasis Ulcer | Monoclonal antibody | Other |cbdMD, Inc.|Last Updated: Aug 26, 2026

Target and mechanism

ModalityMonoclonal antibody

Also known as MTX-001 (human amniotic fluid)

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment80

FDA Designations

No designations recorded

Clinical trial landscape

MTX-001 · 1 trial · 2 indications

Phase 2 1
NCT04647240MTX-001 for the Treatment of Non-Healing Venous Stasis UlcersVenous Stasis Ulcer
RECRUITING80 Analytics
PHASE2RECRUITING
MTX-001 for the Treatment of Non-Healing Venous Stasis Ulcers
Venous Stasis UlcerUnlock trial analytics

Study Endpoints

Primary Endpoints

Safety and tolerability
Baseline to Week 12

Evaluated via patient and/or Investigator reported adverse events that occur during the study

Preliminary efficacy
Baseline to Week 4

Assessed by percentage area reduction of the ulcer surface area from Baseline to Week 4.

Secondary Endpoints

Total wound closure
Baseline to Week 12
Ulcer size
Baseline to Week 12
Change in pain
Baseline to Weeks 4, 8 and 12
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
MTX-001ACTIVE_COMPARATORMTX-001 (human amniotic fluid) solution 0.2 mL/sqcm weekly
Placebo (0.9% saline)PLACEBO_COMPARATORMatching placebo solution 0.2mL/sqcm weekly

Interventions

NameTypeDescription
MTX-001 (human amniotic fluid)BIOLOGICALSubcutaneous injection into and/or around wound bed weekly
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites12

Inclusion Criteria: * Patients who voluntarily give written informed consent to participate in study * Males and female patients aged 18 to 75 years inclusive at Screening (date the patient provides written informed consent to participate in study) for Part 1 only * Males and female patients aged 1...

Countries:United States
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