Recent Updates
Recently added Catalysts

FMX101

Phase 3

Acne Vulgaris | Small molecule | Dermatology |cbdMD, Inc.|Last Updated: Sep 28, 2023

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment372

FDA Designations

No designations recorded

Clinical trial landscape

FMX101 · 1 trial · 1 indication

Phase 3 1
NCT04960930To Evaluate the Efficacy and Safety of Minocycline Hydrochloride Foam in the Treatment of Moderate-to-severe Acne VulgarisAcne Vulgaris
COMPLETED372 Analytics
PHASE3COMPLETED
To Evaluate the Efficacy and Safety of Minocycline Hydrochloride Foam in the Treatment of Moderate-to-severe Acne Vulgaris
Acne VulgarisUnlock trial analytics

Study Endpoints

Primary Endpoints

ILC
Week12

The efficacy assessments will inflammation lesion counts at week12

Secondary Endpoints

Investigator Global Assessment (IGA)
week 12
nILC
week 12
ILC week4
week 4
Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
FMX101EXPERIMENTALFMX101 4% minocycline foam
Vehicle FoamPLACEBO_COMPARATORVehicle Foam

Interventions

NameTypeDescription
FMX101DRUGtopically once daily
Unlock Study Design Details

Eligibility Criteria

Age Range9 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites29

Inclusion Criteria: 1. Has completed and signed an appropriately administered Informed Consent Form (ICF) prior to any study-related procedures. Subjects less than 18 years of age (or as required by state law) must sign an Assent Form for the study and a parent or legal guardian must sign the ICF. ...

Countries:China
Unlock Eligibility Criteria

Frequently asked questions about FMX101

What is FMX101 used for?

FMX101 is an investigational small molecule being developed for the treatment of acne vulgaris. It is formulated as a foam containing minocycline hydrochloride and is intended for topical application. The drug is currently in clinical development and has not been approved by regulatory authorities.

What does FMX101 target?

FMX101 contains minocycline hydrochloride, an antibiotic that works by inhibiting bacterial protein synthesis. It targets Propionibacterium acnes, the bacteria implicated in acne vulgaris, reducing inflammation and bacterial growth in the skin. This mechanism helps treat moderate-to-severe acne.

Who makes FMX101?

FMX101 is being developed by cbdMD, Inc., a company traded on the NYSE American under the ticker symbol YCBD. The company is conducting clinical trials to evaluate the drug's efficacy and safety for the treatment of acne vulgaris.

What phase is FMX101 in?

FMX101 is in Phase 3 clinical development. A Phase 3 trial has been completed, evaluating the efficacy and safety of minocycline hydrochloride foam in treating moderate-to-severe acne vulgaris. The drug remains investigational and is not yet approved for commercial use.

What clinical trials is FMX101 in?

FMX101 has one completed Phase 3 clinical trial, identified as NCT04960930. This randomized, double-blind, placebo-controlled study enrolled 372 participants in China to evaluate the efficacy and safety of minocycline hydrochloride foam in treating moderate-to-severe acne vulgaris. The trial included participants aged 9 years and older.

Is FMX101 the same as minocycline hydrochloride foam?

FMX101 is the brand name for a minocycline hydrochloride foam formulation. The active ingredient is minocycline hydrochloride, an antibiotic. The drug is being developed specifically as a topical foam for acne vulgaris, and the clinical trial NCT04960930 evaluates this formulation.