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CEL383

Phase 1

Healthy | Small molecule | Other |cbdMD, Inc.|Last Updated: Feb 9, 2024

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment48

FDA Designations

No designations recorded

Clinical trial landscape

CEL383 · 1 trial · 1 indication

Phase 1 1
NCT05901883First-in-human, Single Ascending Dose Study of CEL383 in Healthy Adult SubjectsHealthy
COMPLETED48 Analytics
PHASE1COMPLETED
First-in-human, Single Ascending Dose Study of CEL383 in Healthy Adult Subjects
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Treatment-emergent adverse events (TEAEs)
Through the Day 85 study visit

Incidence of TEAEs by type, severity, seriousness, and relationship

Secondary Endpoints

Cmax
Day 1 through Day 85
Tmax
Day 1 through Day 85
t1/2
Day 1 through Day 85
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
CEL383 ArmEXPERIMENTALSubjects will receive a single intravenous dose of CEL383
Placebo ArmPLACEBO_COMPARATORSubjects will receive a single intravenous dose of placebo

Interventions

NameTypeDescription
CEL383DRUGSubjects will receive CEL383
PlaceboDRUGSubjects will receive placebo
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Eligibility Criteria

Age Range19 Years to 64 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Healthy, adult, male or female (of nonchildbearing potential only), 19-64 years of age, inclusive, at screening visit * Willingness of men of reproductive potential to agree to use a condom with spermicide or abstain from heterosexual intercourse from dosing until at least 90 ...

Countries:United States
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Frequently asked questions about CEL383

What is CEL383?

CEL383 is an investigational small molecule being developed by cbdMD, Inc. (ticker: YCBD). It is currently in Phase 1 clinical development. The drug is being studied in healthy adult subjects, and its therapeutic area is classified as Other.

What is CEL383 used for?

CEL383 is being studied for use in healthy adult subjects. It is currently in Phase 1 clinical development, with a completed first-in-human trial. The drug is not approved for any indication and remains investigational.

Who makes CEL383?

CEL383 is being developed by cbdMD, Inc., a company traded under the ticker YCBD. The company is conducting clinical trials to evaluate the safety and tolerability of this investigational small molecule in healthy subjects.

What phase is CEL383 in?

CEL383 is in Phase 1 clinical development. A first-in-human, single ascending dose study has been completed. The drug is investigational and has not been approved by regulatory authorities.

What clinical trials is CEL383 in?

CEL383 has one completed Phase 1 clinical trial, identified as NCT05901883. This was a first-in-human, single ascending dose study in 48 healthy adult subjects in the United States. The trial was randomized, double-blind, and placebo-controlled.

Is CEL383 FDA approved?

CEL383 is not FDA approved. It is an investigational drug currently in Phase 1 clinical development. A first-in-human study has been completed, but the drug remains under clinical investigation and has not received regulatory approval.