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CD-NP

Phase 2

Acute Decompensated Heart Failure | Small molecule | Cardiovascular |cbdMD, Inc.|Last Updated: Mar 25, 2009

Success Probability

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Market & Valuation

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Trial Design

CONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment30

FDA Designations

No designations recorded

Clinical trial landscape

CD-NP · 1 trial · 1 indication

Phase 2 1
NCT00699712Study to Assess Hemodynamic Effects, Safety and Tolerability of Chimeric Natriuretic Peptide (CD-NP) in Patients With Stabilized Acute Heart Failure (AHF)Acute Decompensated Heart Failure
COMPLETED30 Analytics
PHASE2COMPLETED
Study to Assess Hemodynamic Effects, Safety and Tolerability of Chimeric Natriuretic Peptide (CD-NP) in Patients With Stabilized Acute Heart Failure (AHF)
Acute Decompensated Heart FailureUnlock trial analytics

Study Endpoints

Primary Endpoints

Changes in cardiac output and wedge pressure
8 hours

Secondary Endpoints

Changes in additional hemodynamic measures
8 hours
Diuresis and natriuresis during and after administration of study drug
36 hour
Safety of CD-NP
30 Days
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
AEXPERIMENTALOpen-label regimen of doses 1 and 2 of CDNP
BEXPERIMENTALOpen-label regimen of doses 2 and 3 of CDNP
CEXPERIMENTALOpen-label regimen of doses 3 and 4 of CDNP

Interventions

NameTypeDescription
CD-NP (Chimeric natriuretic peptide)DRUGInfusion of CDNP at two of four doses
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Key Inclusion Criteria: * Hospitalization for AHF * In need of hemodynamic monitoring Key Exclusion Criteria: * Administration of intravenous radiographic contrast agent within 7 days prior to screening or planned IV contrast media administration in the 4 days after screening or acute contrast-in...

Countries:Russia
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Frequently asked questions about CD-NP

What is CD-NP used for?

CD-NP is an investigational small molecule being developed for the treatment of Acute Decompensated Heart Failure. It is a chimeric natriuretic peptide studied for its hemodynamic effects in patients with stabilized acute heart failure. The drug is currently in clinical development and has not been approved by regulatory authorities.

Who makes CD-NP?

CD-NP is being developed by cbdMD, Inc., a company traded on the stock exchange under the ticker YCBD. The drug is in Phase 2 clinical development for Acute Decompensated Heart Failure, a cardiovascular condition.

What phase is CD-NP in?

CD-NP is in Phase 2 clinical development. It is an investigational drug, meaning it has not yet been approved for commercial use. A Phase 2 clinical trial has been completed to assess its hemodynamic effects, safety, and tolerability in patients with stabilized acute heart failure.

What clinical trials is CD-NP in?

CD-NP has one completed clinical trial registered under NCT00699712. This Phase 2 study assessed hemodynamic effects, safety, and tolerability of CD-NP in patients with stabilized acute heart failure. The trial enrolled 30 participants in Russia and included patients aged 18 years and older.

Is CD-NP the same as chimeric natriuretic peptide?

Yes, CD-NP is also known as chimeric natriuretic peptide. The clinical trial NCT00699712 refers to the drug as 'Chimeric Natriuretic Peptide (CD-NP)' in its title. This alternative name may be used in scientific literature and clinical trial registries.