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122-0551 Foam

Phase 3

Plaque Psoriasis | Small molecule | Dermatology |cbdMD, Inc.|Last Updated: Nov 8, 2018

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDBiomarker
Total Trials1
Total Enrollment144

FDA Designations

No designations recorded

Clinical trial landscape

122-0551 Foam · 1 trial · 1 indication

Phase 3 1
NCT02367911A Comparison of 122-0551 Foam Versus Vehicle Foam in Subjects With Plaque PsoriasisPlaque Psoriasis
COMPLETED144 Analytics
PHASE3COMPLETED
A Comparison of 122-0551 Foam Versus Vehicle Foam in Subjects With Plaque Psoriasis
Plaque PsoriasisUnlock trial analytics

Study Endpoints

Primary Endpoints

Percentage of Subjects Rated a "Treatment Success" Based on the Investigator's Global Assessment (IGA)
Day 15

The IGA score is a static evaluation of the overall or "average" degree of severity of a subject's disease, taking into account all of the subject's psoriatic lesions. "Treatment success" is defined as a score of 0 or 1 representing "cleared" or "almost cleared" at Day 15 with at least a two grade decrease in severity score relative to Baseline. IGA is measured on a 5-point scale, ranging from 0 (clear) to 4 (severe).

Secondary Endpoints

Percentage of Subjects Rated a "Treatment Success" for Each of the Clinical Signs of Psoriasis (Scaling, Erythema and Plaque Elevation)
Day 15
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Active ArmEXPERIMENTAL122-0551 Foam, topically applied twice daily for two weeks
Vehicle ArmPLACEBO_COMPARATORVehicle Foam, topically applied twice daily for two weeks

Interventions

NameTypeDescription
122-0551 FoamDRUG122-0551 Foam applied twice daily to treat psoriasis
Vehicle FoamDRUGVehicle Foam applied twice daily to treat psoriasis
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites9

Inclusion Criteria: * Subject has a clinical diagnosis of stable plaque psoriasis involving a minimum of 2% and no more than 12% affected body surface area. * Subject has an Investigator's Global Assessment (IGA) score of at least three (moderate) at study start. * If subject is a woman of childbea...

Countries:United States
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Frequently asked questions about 122-0551 Foam

What is 122-0551 Foam used for?

122-0551 Foam is an investigational small molecule being developed for the treatment of plaque psoriasis. It is a topical foam formulation designed for application to the skin. The drug is currently in Phase 3 clinical development and has not been approved by the FDA.

Who makes 122-0551 Foam?

122-0551 Foam is being developed by cbdMD, Inc., a company traded on the NYSE American under the ticker symbol YCBD. The company is conducting clinical trials to evaluate the safety and efficacy of this investigational treatment for plaque psoriasis.

What phase is 122-0551 Foam in?

122-0551 Foam is in Phase 3 clinical development. It is an investigational drug and has not yet been approved by regulatory authorities. A Phase 3 clinical trial has been completed to evaluate its effects in patients with plaque psoriasis.

What clinical trials is 122-0551 Foam in?

122-0551 Foam has one completed Phase 3 clinical trial, identified as NCT02367911. This study, titled "A Comparison of 122-0551 Foam Versus Vehicle Foam in Subjects With Plaque Psoriasis," enrolled 144 participants in the United States. The trial was randomized, double-blind, and placebo-controlled.

Is 122-0551 Foam the same as any other drug?

No alternative names for 122-0551 Foam have been reported. It is identified solely by this name in clinical trial records. The drug is being studied specifically for plaque psoriasis and is not known to be marketed under any other brand name.