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XORTX Therapeutics Inc.

XRTXFDA catalysts, PDUFA dates & pipeline intelligence
$0.97
▲ +0.05 · +5.43%

Financials

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52W LOW $0.8352W HIGH $3.60
Volume
1.30 M
Value Traded
1.37 M
Short % Float
7.34%
Days to Cover
2.1
+10.88%Week
-35.32%1 Month
-53.18%3 Month
-61.04%6 Month
-98.57%5 Year
-98.57%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
  • Dilution Risk
  • SEC Filing

Key Stats

Market Cap
1.76 M
EPS (TTM)
-2.63
P/E Ratio
-
Ent. Value
2.80 M
Total Shares
1.82 M
Float Shares
1.67 M
Insiders
7.84%
Institutions
2.20%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
IND Submission
XRx-026 (XORLO™ oxypurinol)
gout
INDSmall MoleculesDigestive System
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

XRTX Catalyst Timeline

Dated clinical, regulatory and corporate events for XORTX Therapeutics Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for XORTX Therapeutics Inc.

320Total events
5Upcoming
45Tier-1 (high impact)
2018 to 2027Coverage

Upcoming catalysts 2

T1NDA Submission
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XORLO
TBD
T2Equity Offering
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Event history 50

●Quarterly UpdateCorporate
Computershare becomes transfer agent
●Quarterly UpdateCorporate
Refund of funds from IR Agency LLC
●Partnership / LicenseCorporate
Termination of investor relations agreement with IR Agency LLC
●Management ChangeCorporate
Anthony Giovinazzo steps down from board of directors
●Management ChangeCorporate
Depesh Narotam appointed as independent director
◆Type B MeetingXORLOFDA Meeting
FDA Type B meeting feedback received for XRx-026 program
◆Management ChangeCorporate
Appointment of Mika Grasso as Co-CEO
▼Equity OfferingCorporate
Recent financing completed
▼Restructuring LayoffsCorporate
Voluntary delisting from TSX Venture Exchange
▼Equity OfferingCorporate
Closing of US$5 million public offering of common shares and pre-funded warrants
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How XRTX actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

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Every scored asset with PTRS, rNPV, enrollment velocity and trial design quality.
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Clinical Trial Results

Readouts, endpoints and source filings for every XRTX program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
XORLOTM
Orphan
autosomal dominant polycystic kidney disease (ADPKD)Phase 32023-01-19substantial increase in the bioavailability of oxypurinol with the XORLOTM formulation platform; increased dose proportionality compared to non-formulated oxypurinol; average increase of exposure of ~40% in oxypurinol compared to the fasted state; increased bioavailability of 100% or more could be achieved with test formulations compared to non-formulated oxypurinol aloneRead MoreXORTX Announces Positive Topline Results from XRX-OXY-101 Clinical TrialRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
No hedge fund reported a 13F position in XRTX for Q2 2026.
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

Ownership Trends

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Insider and institutional ownership, quarter by quarter.

XRTX Short Interest

Shares sold short, counted twice a month.

7.34%
Short % of Float
of tradable shares sold short
122.5K
Shares Sold Short
-48.3% vs prior count
2.1 Moderate
Days to Cover
trading days of normal volume to buy every short share back
58.4K
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Live calls and puts by strike: last price, volume and open interest for every expiry.
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Calls vs Puts by Expiry

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Competitive positioning

How XRTX ranks across every disease it competes in

Competitive Position is a premium feature
See how XRTX ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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XRTX News

-XRTX
Nov 13, 2026
XRTXFDA Updates
▲ +5.4%today

XORTX Patent Allowed for XRx-101 Program by Japan Patent Office

XORTX Therapeutics announced that the Japan Patent Office has granted a patent for its xanthine oxidase inhibitor compositions aimed at treating acute kidney injury. This patent will support the XRx-101 program and is expected to remain effective until March 2041. The decision enhances XORTX's intellectual property portfolio in Japan, a significant pharmaceutical market.

Read more →
-XRTX
Oct 8, 2026
XRTXFDA Updates
▼ -23.8%on this news

XORTX Outlines Anticipated Health Canada Clinical Trial Application for XRx-026 for Gout

XORTX Therapeutics plans to submit a Clinical Trial Application for XRx-026 to Health Canada. This application supports a two-part clinical study evaluating XORLO™, a proprietary formulation for gout treatment. The initiative aims to expedite clinical data delivery for a subsequent New Drug Application to the FDA. The company has received inquiries from potential commercialization partners as it advances its regulatory strategy.

Read more →
-XRTX
Sep 18, 2026
XRTXFDA Updates
▲ +15.7%on this news

XORTX Announces Planned FDA IND Submission for XRx-026 Gout Program Using XORLO™, Targeting USD$700M+ U.S. Gout Market Opportunity

XORTX Therapeutics plans to submit an Investigational New Drug application for its XRx-026 gout program to the FDA. The submission is expected in the fourth quarter of 2026, following a two-part clinical trial aimed at characterizing the drug's pharmacokinetics and efficacy. The company estimates a market opportunity exceeding USD $700 million based on previous sales of gout treatments. Successful completion of the trial may lead to a New Drug Application submission within a year.

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-XRTX
Sep 10, 2026
XRTXPhases
▲ +10.4%on this news

XORTX Announces Initiation of Clinical and Commercial Manufacturing of XORLO™

XORTX Therapeutics has commenced the manufacturing of drug substance and tablets for XORLO™, a treatment for gout. This initiative supports the XRX-OXY-102 clinical study, which follows positive previous trial results. The company is collaborating with a contract manufacturer to ensure the necessary materials for FDA marketing approval. Further updates on regulatory strategies are expected soon.

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-XRTX
Sep 8, 2026
XRTXGeneral
▼ -5.4%on this newsshared move

XORTX Re-Engages Investor Relations Program

XORTX Therapeutics Inc. has re-engaged IR Agency LLC for investor relations services following its voluntary delisting from the TSX Venture Exchange. The consulting agreement mirrors previous terms disclosed in earlier news releases. The company is focused on developing treatments for gout and other kidney-related conditions.

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-XRTX
Aug 28, 2026
XRTXGeneral

XORTX Announces Termination and Postponement of Investor Relations Program

XORTX Therapeutics has terminated its investor relations agreement with IR Agency LLC and postponed its marketing program as it prepares for a voluntary delisting from the TSX Venture Exchange. The decision aims to reduce regulatory complexity and focus on advancing clinical development. The company plans to re-engage IR Agency LLC post-delisting, expected by September 1, 2026.

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-XRTX
Jul 31, 2026
XRTXGeneral

XORTX Announces Director Resignation

XORTX Therapeutics Inc. announced the resignation of Anthony Giovinazzo from its board of directors for personal reasons. Dr. Allen Davidoff, co-CEO, expressed gratitude for Giovinazzo's contributions during his tenure. XORTX is focused on developing therapies for gout and kidney diseases, with several products in various stages of development.

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-XRTX
Jul 29, 2026
XRTXGeneral

XORTX Appoints New Director

XORTX Therapeutics has appointed Depesh Narotam as an independent director effective July 27, 2026. Narotam brings over 20 years of experience in financial services, particularly in debt financing and strategic partnerships. His appointment is expected to enhance the board's governance and support the advancement of the company's clinical programs targeting gout and kidney diseases.

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-XRTX
Jun 15, 2026
XRTXGeneral

XORTX Provides Corporate Update and Announces Appointment of Mika Grasso as Co-CEO

XORTX Therapeutics has announced the appointment of Mika Grasso as Co-CEO and provided a corporate update focusing on its lead program for gout, XRx-026. The company aims to restructure its corporate status and re-initiate drug development programs, with a clear regulatory pathway for submitting a new drug application. Increased investor interest has allowed for expanded activities in drug development, particularly targeting the gout market.

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-XRTX
Jun 12, 2026
XRTXGeneral

XORTX Announces Election to Voluntary Delist from the TSX Venture Exchange

XORTX Therapeutics has announced its decision to voluntarily delist from the TSX Venture Exchange to reduce costs and streamline operations. The company believes this move will enhance focus on its lead program for gout treatment, XRx-026. Shareholders will still have access to their shares on Nasdaq, and no action is required from them.

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-XRTX
May 19, 2026
XRTXGeneral
▼ -10.8%on this news

XORTX Announces Closing of US$5 Million Public Offering

XORTX Therapeutics has successfully closed a public offering, raising $5 million by issuing 2,659,574 common shares and pre-funded warrants. The funds will support working capital and corporate activities, including investor relations. The offering is subject to final approval from the TSX Venture Exchange. XORTX is focused on developing therapies for gout and kidney diseases.

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-XRTX
May 14, 2026
XRTXGeneral
▼ -14.1%on this newsshared move

XORTX Announces US$5 Million Public Offering

XORTX Therapeutics Inc. has announced a public offering of 2,659,574 common shares priced at $1.88 each, aiming to raise $5 million. The offering is expected to close on or about May 15, 2026, pending regulatory approvals. XORTX is focused on developing therapies for gout and progressive kidney disease, with several products in various stages of development.

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-XRTX
Apr 21, 2026
XRTXGeneral
▲ +19.6%on this news· ran to +35% by day 3

XORTX Meets Nasdaq Continued Listing Requirements

XORTX Therapeutics Inc. has received a compliance letter from Nasdaq after meeting the minimum bid price requirement of $1.00 per share. This was achieved following a 1 for 5 reverse stock split implemented on April 6, 2026. The company is focused on developing therapies for gout and progressive kidney disease, with several products in various stages of development.

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-XRTX
Apr 14, 2026
XRTXGeneral

XORTX Announces Closing of Acquisition of Vectus Kidney Anti-fibrotic Asset

XORTX Therapeutics has finalized the acquisition of the Vectus kidney anti-fibrotic asset, VB4-P5, which targets chronic kidney disease. The program is at the pre-IND stage and addresses a significant unmet medical need. The acquisition includes intellectual property and data from Vectus, enhancing XORTX's development pipeline.

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-XRTX
Apr 1, 2026
XRTXGeneral

XORTX Confirms Effective Date of Share Consolidation

XORTX Therapeutics Inc. has confirmed the effective date for its share consolidation, which will occur on April 6, 2026. This consolidation will be on the basis of one new common share for every five old common shares. The company has received all required approvals from the TSX Venture Exchange and Nasdaq Stock Exchange. XORTX is focused on developing therapies for gout and progressive kidney disease.

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-XRTX
Mar 26, 2026
XRTXGeneral
▼ -9.7%on this news

XORTX Announces Change of Effective Date of Share Consolidation

XORTX Therapeutics has announced a delay in the effective date of its share consolidation from March 27, 2026, to April 6, 2026. This decision is subject to the necessary approvals from the TSX Venture Exchange and Nasdaq. The company focuses on developing therapies for gout and progressive kidney disease, with several products in various stages of development.

Read more →
-XRTX
Mar 26, 2026
XRTXGeneral
▼ -9.7%on this news

XORTX Announces Results of Annual and Special Meeting of Shareholders

XORTX Therapeutics Inc. announced the results of its annual and special meeting held on March 24, 2026. Approximately 35% of shares were represented, leading to the approval of all proposed matters, including the election of five management nominees and the appointment of auditors. The company continues to focus on developing therapies for gout and kidney diseases.

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-XRTX
Mar 25, 2026
XRTXGeneral

XORTX Announces Share Consolidation

XORTX Therapeutics Inc. has announced a share consolidation of one post-consolidation share for every five pre-consolidation shares, effective March 27, 2026. This decision, approved by the TSX Venture Exchange, aims to ensure compliance with NASDAQ's listing requirements. The total number of outstanding shares will decrease significantly, and shareholders will receive instructions for exchanging their shares following the effective date.

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-XRTX
Mar 24, 2026
XRTXGeneral

XORTX Reports that Shareholders Approved the Share Consolidation at the Annual General Meeting

XORTX Therapeutics Inc. announced that shareholders approved a share consolidation at the annual meeting held on March 24, 2026. The consolidation aims to maintain compliance with NASDAQ listing requirements, specifically ensuring shares trade above $1.00. The company currently has 6,962,218 common shares outstanding and plans to consolidate them at a ratio of five to one. The exact number of shares post-consolidation will depend on the rounding of fractional shares.

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-XRTX
Mar 18, 2026
XRTXGeneral
▲ +6.4%on this news

XORTX Announces Substitute Director Nominees for its Upcoming Annual and Special Meeting of Shareholders

XORTX Therapeutics Inc. has proposed three new director nominees for its upcoming annual and special meeting of shareholders scheduled on March 24, 2026. This change arises as part of the company's negotiations for a significant financing initiative. However, this move is conditional; if the financing does not proceed, the new nominees will resign from their positions. The company is encouraging shareholders to vote in favor of the resolutions at the meeting.

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About XORTX Therapeutics Inc.

3 employees xortx.com
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