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VTX3232

Phase 2

Idiopathic Parkinson Disease | Small molecule | Neurology |Ventyx Biosciences, Inc.|Last Updated: Apr 15, 2026

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment11

FDA Designations

No designations recorded

Clinical trial landscape

VTX3232 · 1 trial · 1 indication

Phase 2 1
NCT06556173Phase 2a Study of VTX3232 in Parkinson's DiseaseIdiopathic Parkinson Disease
COMPLETED11 Analytics
PHASE2COMPLETED
Phase 2a Study of VTX3232 in Parkinson's Disease
Idiopathic Parkinson DiseaseUnlock trial analytics

Study Endpoints

Primary Endpoints

Adverse Event (AE) / Serious Adverse Event (SAE) Incidence Rate and Severity through study completion
Day 1 of treatment period through study completion, up to 6 weeks

Incidence of AEs and SAEs

Secondary Endpoints

Pharmacokinetics (PK) of VTX3232 in plasma and Cerebrospinal Fluid (CSF) at Day 28
Day 1 of treatment period to Day 28 of treatment period
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
VTX3232 Dose AEXPERIMENTAL -

Interventions

NameTypeDescription
VTX3232DRUGDose A
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Eligibility Criteria

Age Range40 Years to 80 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Participants must be ≥ 40 years up to 80 years of age, inclusive, at the time of signing the informed consent, with BMI \> 18.5 and \< 32.0 kg/m2 and body weight ≥ 50.0 kg for males and ≥ 45.0 kg for females. * Diagnosis of idiopathic Parkinson's Disease between 0 and 60 month...

Countries:United States
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Frequently asked questions about VTX3232

What is VTX3232 used for?

VTX3232 is an investigational small molecule being developed for the treatment of idiopathic Parkinson disease. It is currently in Phase 2 clinical development and has not been approved by regulatory authorities.

Who makes VTX3232?

VTX3232 is being developed by Ventyx Biosciences, Inc., a biopharmaceutical company traded on the NASDAQ under the ticker symbol VTYX.

What phase is VTX3232 in?

VTX3232 is in Phase 2 clinical development. It is an investigational drug and has not been approved for any use. A Phase 2a study has been completed.

What clinical trials is VTX3232 in?

VTX3232 has one completed clinical trial, NCT06556173, a Phase 2a study in Parkinson's disease. This trial enrolled 11 participants with idiopathic Parkinson disease in the United States.

Is VTX3232 FDA approved?

VTX3232 is not FDA approved. It is an investigational drug currently in Phase 2 clinical development for idiopathic Parkinson disease, and its safety and efficacy have not been established.