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system containing progestin

Phase 3

Female Contraception | Small molecule | Endocrine |Viatris Inc.|Last Updated: May 6, 2026

Target and mechanism

ModalitySmall molecule

Also known as Transdermal system containing progestin

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment1,630

FDA Designations

No designations recorded

Clinical trial landscape

system containing progestin · 1 trial · 1 indication

Phase 3 1
NCT06672016Study to Evaluate Contraceptive Efficacy and Safety of a Progestin Only Patch in Women of Childbearing PotentialFemale Contraception
ACTIVE NOT_RECRUITING1,630 Analytics
PHASE3ACTIVE NOT_RECRUITING
Study to Evaluate Contraceptive Efficacy and Safety of a Progestin Only Patch in Women of Childbearing Potential
Female ContraceptionUnlock trial analytics

Study Endpoints

Primary Endpoints

To determine the contraceptive efficacy of progestin only patch when used over 13 cycles
13 cycles [of 4 weeks (28 days)

The primary efficacy endpoint will be pregnancy rate described by Pearl Index (PI). PI is defined as the number of pregnancies per 100 women-years.

Secondary Endpoints

To determine the efficacy in obese population (Body mass index (BMI) ≥30.0 kg/m2)
13 cycles [of 4 weeks (28 days)
To determine the efficacy in non-obese population (Body mass index (BMI) <30.0 kg/m2)
13 cycles [of 4 weeks (28 days)
Cycle-wise and cumulative pregnancy rates over 1 year
13 cycles [of 4 weeks (28 days)
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposePREVENTION

Treatment Arms

ArmTypeDescription
This is a single-arm study.EXPERIMENTALThe study patch is a transdermal system that contains the active ingredient progestin. This study is an open-label, single-arm study. This means that all participants in the study will receive the study patch

Interventions

NameTypeDescription
Transdermal system containing progestinDRUGMR-130A-01 transdermal system, patch to be used for female contraception
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Eligibility Criteria

Age Range16 Years to N/A
SexFEMALE
Healthy VolunteersNo
Study Sites56

Inclusion Criteria: 1. Healthy, post-menarcheal and premenopausal women at risk of pregnancy who are at least 16 years of age. 2. Desires to avoid pregnancy, is seeking to use hormonal contraception for at least 1 year. 3. Has negative UPT results at screening and at enrollment visits. 4. Has norma...

Countries:United States
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Frequently asked questions about system containing progestin

What is the system containing progestin used for?

The system containing progestin is used for female contraception. It is a progestin-only patch being studied in women of childbearing potential. The drug is currently in Phase 3 clinical development and is not yet approved by the FDA.

Who makes the system containing progestin?

Viatris Inc. (ticker: VTRS) is developing the system containing progestin. The company is conducting a Phase 3 clinical trial to evaluate the contraceptive efficacy and safety of this progestin-only patch in women of childbearing potential.

What phase is the system containing progestin in?

The system containing progestin is in Phase 3 clinical development. It is an investigational drug and has not been approved by the FDA. The ongoing Phase 3 trial is active but not recruiting participants.

What clinical trials is the system containing progestin in?

The system containing progestin is being studied in one Phase 3 clinical trial, NCT06672016, titled 'Study to Evaluate Contraceptive Efficacy and Safety of a Progestin Only Patch in Women of Childbearing Potential.' The trial is active but not recruiting, with an enrollment of 1630 participants in the United States.

Is the system containing progestin the same as the transdermal system containing progestin?

Yes, the system containing progestin is also known as the transdermal system containing progestin. It is a progestin-only patch being developed by Viatris Inc. for female contraception, currently in Phase 3 clinical trials.