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Zonisamide

Phase 1

Healthy | Small molecule | Other |Viatris Inc.|Last Updated: Apr 23, 2024

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedACTIVE_CONTROLLEDBiomarker
Total Trials2
Total Enrollment217
FDA Designations
No designations recorded
Clinical Trials (2)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00649714Fed Study of Zonisamide Capsules 100 mg and Zonegran® Capsules 100 mgPHASE1 COMPLETED 110Dec 1, 2003Jan 1, 2004Apr 23, 20241 United States
NCT00650052Fasting Study of Zonisamide Capsules 100 mg and Zonegran® Capsules 100 mgPHASE1 COMPLETED 107Nov 1, 2003Dec 1, 2003Apr 23, 20241 United States
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Study Endpoints
Primary Endpoints
Bioequivalence
within 30 days
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Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelPARALLEL
PurposeOTHER
Treatment Arms
ArmTypeDescription
1EXPERIMENTALZonisamide Capsules 100 mg
2ACTIVE_COMPARATORZonegran® Capsules 100 mg
Interventions
NameTypeDescription
Zonisamide Capsules 100 mgDRUG100mg, single dose fed
Zonegran® Capsules 100 mgDRUG100mg, single dose fed
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Eligibility Criteria
Age Range18 Years — N/A
SexMALE
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Age: 18 years and older. 2. Sex: Male. 3. Weight: At least 60 kg (132 lbs) and within 15% of Ideal Body Weight (IBW), as referenced by the Table of ""Desirable Weights of Adults"" Metropolitan Life Insurance Company, 1999 (See Part II ADMINISTRATIVE ASPECTS OF BIOEQUIVALENCE ...

Countries:United States
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