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Paxil

Phase 1

Healthy | Small molecule | Other |Viatris Inc.|Last Updated: Apr 24, 2024

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedACTIVE_CONTROLLEDBiomarker
Total Trials3
Total Enrollment216
FDA Designations
No designations recorded
Clinical Trials (3)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00650403Food Study of Paroxetine Hydrochloride Tablets 40 mg and Paxil® Tablets 40 mgPHASE1 COMPLETED 66Dec 1, 2006Jan 1, 2007Apr 24, 20241 United States
NCT00647881Food Study of Paroxetine Hydrochloride Controlled-Release Tablets 25 mg to Paxil CR™ Tablets 25 mgPHASE1 COMPLETED 75Apr 1, 2005May 1, 2005Apr 24, 20241 United States
NCT00648427Fasting Study of Paroxetine Hydrochloride Controlled-Release Tablets 25 mg to Paxil CR™ Tablets 25 mgPHASE1 COMPLETED 75Apr 1, 2005May 1, 2005Apr 24, 20241 United States
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Study Endpoints
Primary Endpoints
Bioequivalence
within 30 days
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Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeOTHER
Treatment Arms
ArmTypeDescription
1EXPERIMENTALParoxetine hydrochloride 40 mg tablet
2ACTIVE_COMPARATORPaxil® 40 mg Tablet
Interventions
NameTypeDescription
Paroxetine hydrochloride 40 mg tabletDRUG40mg, single dose fed
Paxil® 40 mg TabletDRUG40mg, single dose fed
Paroxetine Hydrochloride Controlled-Release Tablets 25 mgDRUG25mg, single dose fed
Paxil CR™ Tablets 25 mgDRUG25mg, single dose fed
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Subjects who were informed of the nature of the study and agreed to read, review, and sign the informed consent document prior to Period I dosing. 2. Subjects who completed the screening process within 21 days prior to Period I dosing. 3. Subjects who were healthy adult men a...

Countries:United States
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