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Oxybutynin Chloride

Phase 1

Healthy | Small molecule | Other |Viatris Inc.|Last Updated: Apr 24, 2024

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLEDBiomarker
Total Trials2
Total Enrollment88

FDA Designations

No designations recorded

Clinical trial landscape

Oxybutynin Chloride · 2 trials · 1 indication

Phase 1 2
NCT00648843Food Study of Oxybutynin Chloride Extended-release Tablets 5 mg and Ditropan XL® Tablets 5 mgHealthy
COMPLETED28 Analytics
NCT00650481Fasting Study of Oxybutynin Chloride Extended-release Tablets 5 mg and Ditropan XL® Tablets 5 mgHealthy
COMPLETED60 Analytics
PHASE1COMPLETED
Food Study of Oxybutynin Chloride Extended-release Tablets 5 mg and Ditropan XL® Tablets 5 mg
HealthyUnlock trial analytics
PHASE1COMPLETED
Fasting Study of Oxybutynin Chloride Extended-release Tablets 5 mg and Ditropan XL® Tablets 5 mg
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Bioequivalence
within 30 days
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeOTHER

Treatment Arms

ArmTypeDescription
1EXPERIMENTALOxybutynin Chloride Extended-release Tablets 5 mg
2ACTIVE_COMPARATORDitropan XL® Tablets 5 mg

Interventions

NameTypeDescription
Oxybutynin Chloride Extended-release Tablets 5 mgDRUG4x5mg, single dose fed
Ditropan XL® Tablets 5 mgDRUG4x5mg, single dose fed
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Age: 18 years and older. 2. Sex: Male and/or non-pregnant, non-lactating female 1. Women of childbearing potential must have negative serum (Beta HCG) pregnancy tests performed within 14 days prior to the start of the study and on the evening prior to each dose administra...

Countries:United States
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Frequently asked questions about Oxybutynin Chloride

What is Oxybutynin Chloride used for?

Oxybutynin Chloride is an investigational small molecule being studied in healthy volunteers. It is being developed by Viatris Inc. (VTRS) and is currently in Phase 1 clinical development. The drug is being evaluated in pharmacokinetic studies comparing extended-release tablets to a reference product.

Who makes Oxybutynin Chloride?

Oxybutynin Chloride is being developed by Viatris Inc., a pharmaceutical company traded on the NASDAQ under the ticker VTRS. The company is conducting Phase 1 clinical trials to evaluate the drug's pharmacokinetic profile in healthy adult volunteers.

What phase is Oxybutynin Chloride in?

Oxybutynin Chloride is in Phase 1 clinical development. Two Phase 1 studies have been completed, with a total of 88 participants enrolled. The drug is investigational and has not been approved by regulatory authorities.

What clinical trials is Oxybutynin Chloride in?

Oxybutynin Chloride has two completed Phase 1 trials: NCT00648843, a food study of extended-release tablets 5 mg versus Ditropan XL 5 mg with 28 participants, and NCT00650481, a fasting study with 60 participants. Both were conducted in the United States with healthy volunteers aged 18 and older.

Is Oxybutynin Chloride the same as Ditropan XL?

Oxybutynin Chloride is being studied as a potential generic version of Ditropan XL. The clinical trials compare Oxybutynin Chloride extended-release tablets 5 mg directly against Ditropan XL tablets 5 mg to assess bioequivalence under fed and fasting conditions.