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Mylan Estradiol System/day

Phase 1

Healthy | Small molecule | Other |Viatris Inc.|Last Updated: Apr 1, 2008

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLEDBiomarker
Total Trials1
Total Enrollment76

FDA Designations

No designations recorded

Clinical trial landscape

Mylan Estradiol System/day · 1 trial · 1 indication

Phase 1 1
NCT00649896Evaluation of Adhesion Quality of a New Formulation of the Mylan Estradiol Transdermal System 0.025 mg/Day and Climara® Transdermal System 0.025 mg/DayHealthy
COMPLETED76 Analytics
PHASE1COMPLETED
Evaluation of Adhesion Quality of a New Formulation of the Mylan Estradiol Transdermal System 0.025 mg/Day and Climara® Transdermal System 0.025 mg/Day
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Study Endpoints

Primary Endpoints

Dermal Safety
within 30 days
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Study Design & Arms

AllocationRANDOMIZED
MaskingSINGLE
ModelSINGLE_GROUP

Treatment Arms

ArmTypeDescription
1EXPERIMENTALMylan Estradiol Transdermal System 0.025 mg/day
2ACTIVE_COMPARATORClimara® Transdermal System 0.025 mg/day

Interventions

NameTypeDescription
Mylan Estradiol Transdermal System 0.025 mg/dayDRUG -
Climara® Transdermal System 0.025 mg/dayDRUG -
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Eligibility Criteria

Age Range40 Years to 69 Years
SexFEMALE
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Age: 40-69 years. 2. Sex: Females only. 3. Weight: At least 52 kg (115 lbs) and within 30% of Ideal Body Weight (IBW), as referenced by the Table of "Desirable Weights of Adults" from Metropolitan Life Insurance Company, 1999 (See Part II: ADMINISTRATIVE ASPECTS OF HUMAN BIOA...

Countries:United States
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Frequently asked questions about Mylan Estradiol System/day

What is Mylan Estradiol System/day used for?

Mylan Estradiol System/day is an investigational small molecule being studied in healthy female volunteers. It is a transdermal estradiol system delivering 0.025 mg per day. The drug is currently in Phase 1 clinical development and is not approved by the FDA.

Who makes Mylan Estradiol System/day?

Mylan Estradiol System/day is being developed by Viatris Inc. (NASDAQ: VTRS). The company is conducting clinical trials to evaluate this transdermal estradiol system in healthy volunteers.

What phase is Mylan Estradiol System/day in?

Mylan Estradiol System/day is in Phase 1 clinical development. It is an investigational drug and has not been approved by the FDA. One Phase 1 trial has been completed, with no active trials currently ongoing.

What clinical trials is Mylan Estradiol System/day in?

Mylan Estradiol System/day has one completed clinical trial, NCT00649896. This Phase 1 study evaluated the adhesion quality of the Mylan Estradiol Transdermal System 0.025 mg/day compared to Climara Transdermal System 0.025 mg/day in 76 healthy female volunteers aged 40 years and older in the United States.

Is Mylan Estradiol System/day the same as Climara?

Mylan Estradiol System/day is not the same as Climara, but it was compared to Climara in a clinical trial. The study NCT00649896 evaluated the adhesion quality of the Mylan Estradiol Transdermal System 0.025 mg/day against Climara Transdermal System 0.025 mg/day in healthy female volunteers.