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Modafinil

Phase 1

Healthy | Small molecule | Other |Viatris Inc.|Last Updated: Apr 24, 2024

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
RandomizedACTIVE_CONTROLLEDBiomarker
Total Trials2
Total Enrollment52
FDA Designations
No designations recorded
Clinical Trials (2)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00650000Fasting Study of Modafinil Tablets 200 mg and Provigil® Tablets 200 mgPHASE1 COMPLETED 32Oct 1, 2002Oct 1, 2002Apr 24, 20241 United States
NCT00650286Food Study of Modafinil Tablets 200 mg to Provigil® Tablets 200 mgPHASE1 COMPLETED 20Sep 1, 2002Oct 1, 2002Apr 24, 20241 United States
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Study Endpoints
Primary Endpoints
Bioequivalence
within 30 days
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Study Design & Arms
AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeOTHER
Treatment Arms
ArmTypeDescription
1EXPERIMENTALModafinil Tablets 200 mg
2ACTIVE_COMPARATORProvigil® Tablets 200 mg
Interventions
NameTypeDescription
Modafinil Tablets 200 mgDRUG200mg, single dose fasting
Provigil® Tablets 200 mgDRUG200mg, single dose fasting
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Age: 18 years and older. 2. Sex: Male and non-pregnant, non-lactating female 1. Women of childbearing potential must have negative serum (Beta HCG) pregnancy tests performed within 14 days prior to the start of the study and on the evening prior to each dose administratio...

Countries:United States
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