Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
Lopressor · 2 trials · 1 indication
| Arm | Type | Description |
|---|---|---|
| 1 | EXPERIMENTAL | Metoprolol Tartrate Tablets 25 mg |
| 2 | ACTIVE_COMPARATOR | Lopressor® Tablets 50 mg |
| Name | Type | Description |
|---|---|---|
| Metoprolol Tartrate Tablets 25 mg | DRUG | 2x50mg, single dose fed |
| Lopressor® Tablets 50 mg | DRUG | 1x50mg, single dose fed |
| Metoprolol Tartrate Tablets 100 mg | DRUG | 100mg, single dose fed |
| Lopressor® Tablets 100 mg | DRUG | 100mg, single dose fed |
Inclusion Criteria: 1. Age: 18 years and older. 2. Sex: Male and non-pregnant, non-lactating female 1. Women of childbearing potential must have negative serum beta-human chorionic gonadotropin (HCG) pregnancy tests performed within 14 days prior to the start of the study and the evening prior ...
Lopressor is a small molecule drug being developed by Viatris Inc. (VTRS). It is currently in Phase 1 clinical trials for use in healthy volunteers. The drug is being studied in bioavailability and fed-state studies to compare different tablet strengths.
Lopressor is developed by Viatris Inc., a global healthcare company traded on the NASDAQ under the ticker VTRS. The company is conducting Phase 1 clinical trials to evaluate the drug's pharmacokinetics in healthy subjects.
Lopressor is in Phase 1 clinical development. It is an investigational drug, meaning it has not yet been approved by regulatory authorities. Two Phase 1 studies have been completed, with no active trials currently ongoing.
Lopressor has two completed Phase 1 clinical trials: NCT00648271, a fed study comparing metoprolol tartrate tablets 25 mg to Lopressor 50 mg, and NCT00649116, a fed study comparing metoprolol tartrate tablets 100 mg to Lopressor 100 mg. Both enrolled healthy adults in the United States.
Lopressor is a brand name for metoprolol tartrate. The clinical trials compare Lopressor to generic metoprolol tartrate tablets to assess bioequivalence under fed conditions. The studies enrolled healthy volunteers aged 18 years and older.