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Imiquimod 5 %

Phase 2

Actinic Keratosis | Small molecule | Dermatology |Viatris Inc.|Last Updated: Feb 7, 2022

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLEDBiomarker
Total Trials1
Total Enrollment45

FDA Designations

No designations recorded

Clinical trial landscape

Imiquimod 5 % · 1 trial · 1 indication

Phase 2 1
NCT00189267A Study to Evaluate the Effectiveness and Safety of Multiple Applications of Imiquimod 5% Cream for the Treatment of Actinic Keratoses in Organ Transplant RecipientsActinic Keratosis
COMPLETED45 Analytics
PHASE2COMPLETED
A Study to Evaluate the Effectiveness and Safety of Multiple Applications of Imiquimod 5% Cream for the Treatment of Actinic Keratoses in Organ Transplant Recipients
Actinic KeratosisUnlock trial analytics

Study Endpoints

Primary Endpoints

Primary outcome of the study is to compare imiquimod 5% cream and vehicle cream with respect to safety assessments in graft recipients.

Secondary Endpoints

Secondary outcome of the study is to compare imiquimod 5% cream and vehicle cream with respect to complete and partial clearance rates.
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
Imiquimod 5 % CreamDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo

Inclusion Criteria: * Have a total of 4-10 actinic keratosis (AK) lesions located on either face or scalp * If female and of childbearing potential, have a negative urine pregnancy test at treatment initiation, and willing to use a medically acceptable method of contraception during the treatment p...

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Frequently asked questions about Imiquimod 5 %

What is Imiquimod used for?

Imiquimod is a small molecule drug being developed by Viatris Inc. for the treatment of basal cell carcinoma and actinic keratosis. It is an investigational therapy that has been studied in clinical trials for these skin conditions.

What does Imiquimod target?

Imiquimod is a small molecule drug that works through immune response modulation. It is being studied for its effectiveness in treating superficial basal cell carcinoma and actinic keratosis, particularly in organ transplant recipients.

Who makes Imiquimod?

Imiquimod is being developed by Viatris Inc., a pharmaceutical company traded on the NASDAQ under the ticker symbol VTRS. The company is conducting clinical trials to evaluate the drug's effectiveness in treating certain skin conditions.

What phase is Imiquimod in?

Imiquimod is in Phase 3 clinical development for basal cell carcinoma. It has completed Phase 3 trials, including a study evaluating the effectiveness of Imiquimod 5% cream in superficial basal cell carcinoma with 160 participants.

What clinical trials is Imiquimod in?

Imiquimod has been studied in several completed clinical trials. NCT00189241 was a Phase 3 trial in Germany for basal cell carcinoma with 160 participants. NCT00189267 was a Phase 2 trial for actinic keratosis in organ transplant recipients. NCT00189280 was a Phase 3 trial in France for basal cell carcinoma.

Is Imiquimod the same as Aldara?

Imiquimod is also known as Aldara, as indicated by the clinical trial NCT00189280 titled 'Aldara for the Treatment of Large and/or Multiple sBCC'. This trial evaluated the drug for the treatment of superficial basal cell carcinoma.