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Doxycycline

Phase 1

Healthy | Small molecule | Other |Viatris Inc.|Last Updated: Apr 24, 2024

Target and mechanism

ModalitySmall molecule

Also known as Doxycycline Tablets, 150mg

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLEDBiomarker
Total Trials3
Total Enrollment107

FDA Designations

No designations recorded

Clinical trial landscape

Doxycycline · 3 trials · 1 indication

Phase 1 3
NCT00647959Fasting Study of Doxycycline Monohydrate Tablets 150 mg and Adoxa Tablets 150 mgHealthy
COMPLETED36 Analytics
NCT00648180Food Study of Doxycycline Monohydrate Tablets 100 mg and Adoxa Tablets 100 mgHealthy
COMPLETED36 Analytics
NCT00649571Fasting Study of Doxycycline Monohydrate Tablets 100 mg and Adoxa Tablets 100 mgHealthy
COMPLETED35 Analytics
PHASE1COMPLETED
Fasting Study of Doxycycline Monohydrate Tablets 150 mg and Adoxa Tablets 150 mg
HealthyUnlock trial analytics
PHASE1COMPLETED
Food Study of Doxycycline Monohydrate Tablets 100 mg and Adoxa Tablets 100 mg
HealthyUnlock trial analytics
PHASE1COMPLETED
Fasting Study of Doxycycline Monohydrate Tablets 100 mg and Adoxa Tablets 100 mg
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Bioequivalence
within 30 days
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeOTHER

Treatment Arms

ArmTypeDescription
1EXPERIMENTALDoxycycline Tablets, 150mg
2ACTIVE_COMPARATORAdoxa Tablets 150 mg

Interventions

NameTypeDescription
Doxycycline Tablets, 150mgDRUG150mg, single dose fasting
Adoxa Tablets 150 mgDRUG150mg, single dose fasting
Doxycycline Monohydrate Tablets 100 mgDRUG100mg, single dose fed
Adoxa Tablets 100 mgDRUG100mg, single dose fed
Doxycycline Monohydrate Tablets (100 mgDRUG100mg, single dose fasting
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: 1. Age: 18 years and older. 2. Sex: Male and/or non-pregnant, non-lactating female. 1. Women of childbearing potential must have negative serum beta human chorionic gonadotropin (beta-HCG) pregnancy tests performed within 21 days prior to the start of the study and on the ev...

Countries:United States
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