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BROMOCRIPTINE, USP

Phase 1

Healthy | Small molecule | Other |Viatris Inc.|Last Updated: Apr 24, 2024

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLEDBiomarker
Total Trials2
Total Enrollment239

FDA Designations

No designations recorded

Clinical trial landscape

BROMOCRIPTINE, USP · 2 trials · 1 indication

Phase 1 2
NCT00650520Fed Study of (Parlodel®) 2.5 mg Bromocriptine Mesylate TabletsHealthy
COMPLETED119 Analytics
NCT00649168Fed Study of (Parlodel®) Bromocriptine Mesylate Capsules 5 mgHealthy
COMPLETED120 Analytics
PHASE1COMPLETED
Fed Study of (Parlodel®) 2.5 mg Bromocriptine Mesylate Tablets
HealthyUnlock trial analytics
PHASE1COMPLETED
Fed Study of (Parlodel®) Bromocriptine Mesylate Capsules 5 mg
HealthyUnlock trial analytics

Study Endpoints

Primary Endpoints

Bioequivalence
within 30 days
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Study Design & Arms

AllocationRANDOMIZED
MaskingNONE
ModelCROSSOVER
PurposeOTHER

Treatment Arms

ArmTypeDescription
1EXPERIMENTALMetoclopramide Hydrochloride Injection Sandoz Standard 5mg/mL (10mg/2mL)and BROMOCRIPTINE MESYLATE CAPSULES, USP 5 mg
2ACTIVE_COMPARATORMetoclopramide Hydrochloride Injection Sandoz Standard 5mg/mL (10mg/2mL) and Parlodel® (bromocriptine mesylate) capsules, USP 5 mg

Interventions

NameTypeDescription
BROMOCRIPTINE MESYLATE CAPSULES, USP 5 mgDRUG4x2.5mg bromocriptine mesylate, single dose fed; with 10mg metoclopramide HCl prophylactic injection
Parlodel® (bromocriptine mesylate) capsules, USP 5 mgDRUG4x2.5mg bromocriptine mesylate, single dose fed; with 10mg metoclopramide HCl prophylactic injection
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Eligibility Criteria

Age Range18 Years to 45 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Healthy adult male or female volunteers, 18-45 years of age. * Subjects will be continuous non-smokers for at least 3 months prior to the first dose or consistent moderate smokers (fewer than 10 cigarettes per day) for at least 3 months prior to the first dosing. * Weighi...

Countries:Canada
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Frequently asked questions about BROMOCRIPTINE, USP

What is BROMOCRIPTINE, USP?

BROMOCRIPTINE, USP is a small molecule drug being developed by Viatris Inc. (VTRS). It is currently in Phase 1 clinical development. The drug has been studied in healthy volunteers in clinical trials conducted in Canada.

What is BROMOCRIPTINE, USP used for?

BROMOCRIPTINE, USP is being studied in healthy volunteers. The clinical trials for this drug are Phase 1 studies that enroll healthy participants. The drug is not approved for any specific medical condition and remains in clinical development.

Who makes BROMOCRIPTINE, USP?

BROMOCRIPTINE, USP is being developed by Viatris Inc., a company traded on the stock exchange under the ticker symbol VTRS. Viatris is the sponsor of the clinical trials for this drug.

What phase is BROMOCRIPTINE, USP in?

BROMOCRIPTINE, USP is in Phase 1 clinical development. The drug is investigational and has not been approved by regulatory authorities. It is being studied in early-stage clinical trials involving healthy volunteers.

What clinical trials is BROMOCRIPTINE, USP in?

BROMOCRIPTINE, USP has been studied in two completed Phase 1 clinical trials: NCT00649168 and NCT00650520. Both trials were conducted in Canada and enrolled healthy volunteers. The first trial studied 5 mg capsules and the second studied 2.5 mg tablets.

Is BROMOCRIPTINE, USP the same as Parlodel?

BROMOCRIPTINE, USP is being studied in formulations that are compared to Parlodel. The clinical trials for this drug reference Parlodel in their titles, indicating that BROMOCRIPTINE, USP is being evaluated as a potential generic or alternative version of Parlodel.