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Fasedienol- Fasedienol

Phase 2

Social Anxiety Disorder | Small molecule | Psychiatry |Vistagen Therapeutics, Inc.|Last Updated: Feb 5, 2026

Target and mechanism

ModalitySmall molecule

Also known as Fasedienol Nasal Spray - Fasedienol Nasal Spray

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindCONTROLLED
Total Trials1
Total Enrollment60

FDA Designations

No designations recorded

Clinical trial landscape

Fasedienol- Fasedienol · 1 trial · 1 indication

Phase 2 1
NCT06809179A Clinical Trial to Assess the Efficacy, Safety, and Tolerability of a Repeat Dose of Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety DisorderSocial Anxiety Disorder
RECRUITING60 Analytics
PHASE2RECRUITING
A Clinical Trial to Assess the Efficacy, Safety, and Tolerability of a Repeat Dose of Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder
Social Anxiety DisorderUnlock trial analytics

Study Endpoints

Primary Endpoints

Subjective Units of Distress Scale (SUDS)
7 days (Visit 2 to Visit 3)

The SUDS is a patient self-rated acute measurement scale that is scored in the range of 0 to 100 (operationalized for participants in this study as 0=totally relaxed or no anxiety at all and 100=highest distress or anxiety ever felt.

Secondary Endpoints

Global Impression Scale of Improvement (CGI-I)
7 days (Visit 2 to Visit 3)
Patient Global Impression of Change (PGI-C)
7 days (Visit 2 to Visit 3)
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Study Design & Arms

AllocationRANDOMIZED
MaskingTRIPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Fasedienol Nasal Spray (single dose)EXPERIMENTALTwenty minutes prior to the PSC, subjects will receive one dose of Fasedienol Nasal Spray followed by one dose of Placebo Nasal Spray, separated by 10-minutes in between the two doses.
Fasedienol Nasal Spray (repeat dose)EXPERIMENTALTwenty minutes prior to the PSC, subjects will receive one dose of Fasedienol Nasal Spray followed by a second dose of Fasedienol Nasal Spray, separated by 10-minutes in between the two doses.
Placebo Nasal SprayEXPERIMENTALTwenty minutes prior to the PSC, subjects will receive one dose of Placebo Nasal Spray followed by a second dose of Placebo Nasal Spray, separated by 10-minutes between the two doses.

Interventions

NameTypeDescription
Fasedienol Nasal Spray - Placebo Nasal SprayDRUGTwenty minutes prior to the PSC, subjects will receive one dose of Fasedienol Nasal Spray followed by one dose of Placebo Nasal Spray, separated by 10-minutes in between the two doses.
Fasedienol Nasal Spray - Fasedienol Nasal SprayDRUGTwenty minutes prior to the PSC, subjects will receive one dose of Fasedienol Nasal Spray followed by a second dose of Fasedienol Nasal Spray, separated by 10-minutes in between the two doses.
Placebo Nasal Spray - Placebo Nasal SprayDRUGTwenty minutes prior to the PSC, subjects will receive one dose of Placebo Nasal Spray followed by a second dose of Placebo Nasal Spray, separated by 10-minutes between the two doses.
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites9

Inclusion Criteria: * Written informed consent provided prior to conducting any study-specific assessment. * Male and female adults, 18 through 65 years of age, inclusive. * Current diagnosis of SAD as defined in the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition, and confirmed ...

Countries:United States
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Frequently asked questions about Fasedienol- Fasedienol

What is Fasedienol used for?

Fasedienol is an investigational small molecule nasal spray being studied for the acute treatment of anxiety in adults with Social Anxiety Disorder. It is currently in Phase 2 clinical development and is not yet approved by the FDA.

How does Fasedienol work?

Fasedienol is a small molecule administered as a nasal spray. Its specific molecular target has not been disclosed in available clinical trial information. The drug is being evaluated for its efficacy, safety, and tolerability in reducing anxiety symptoms in patients with Social Anxiety Disorder.

Who is developing Fasedienol?

Fasedienol is being developed by Vistagen Therapeutics, Inc., a biopharmaceutical company traded on the NASDAQ under the ticker symbol VTGN. The company is conducting clinical trials to assess the drug's potential as a treatment for Social Anxiety Disorder.

What phase is Fasedienol in?

Fasedienol is currently in Phase 2 clinical development. It is an investigational drug, meaning it has not received regulatory approval and is still being studied in clinical trials to evaluate its safety and efficacy for the treatment of Social Anxiety Disorder.

What clinical trials is Fasedienol in?

Fasedienol is being studied in a Phase 2 clinical trial with the identifier NCT06809179. This randomized, double-blind, controlled trial is recruiting 60 adult participants in the United States to assess the efficacy, safety, and tolerability of a repeat dose of Fasedienol Nasal Spray for the acute treatment of anxiety in Social Anxiety Disorder.

Is Fasedienol the same as Fasedienol Nasal Spray?

Yes, Fasedienol is also known as Fasedienol Nasal Spray. The drug is administered as a nasal spray formulation and is being investigated for the acute treatment of anxiety in adults with Social Anxiety Disorder.