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VP-102 Cantharidin film forming

Phase 2

Common Wart | Small molecule | Oncology |Verrica Pharmaceuticals Inc.|Trials Updated: Nov 27, 2024

VP-102 Cantharidin film forming target and mechanism

ModalitySmall molecule

Also known as VP-102 Cantharidin topical film forming solution

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment56

FDA Designations

No designations recorded

VP-102 Cantharidin film forming clinical trials

VP-102 Cantharidin film forming · 1 trial · 12 indications

Phase 2 1
NCT03487549Cantharidin and Occlusion in Verruca EpitheliumCommon Wart
COMPLETED56 Analytics
PHASE2COMPLETED
Cantharidin and Occlusion in Verruca Epithelium
Common WartUnlock trial analytics

Study Endpoints

Primary Endpoints

Cohort 1: Proportion of Subjects Exhibiting Complete Clearance of All Treatable Warts (Baseline and New) at the EOS Visit (Day 84)
Treatment Visit Day 1 (Baseline) compared to Day 84 (EOS) Visit.

Cohort 1: Proportion of subjects exhibiting complete clearance of all treatable warts (baseline and new) at the EOS Visit (Day 84).

Cohort 2: Proportion of Subjects Exhibiting Complete Clearance of All Treatable Warts (Baseline and New) at the EOT Visit (Day 84)
Compare Treatment Visit 1 (Baseline) to EOT Visit (Day 84)

Cohort 2: Proportion of subjects exhibiting complete clearance of all treatable warts (baseline and new) at the EOT Visit (Day 84).

Secondary Endpoints

Cohort 1: Change From Baseline in the Number of Treatable Warts (Baseline and New) at the EOS Visit (Day 84)
Change in the number of warts compared at Baseline (Visit 1) to the End of Study Visit (Day 84).
Cohort 1: Percent Change From Baseline in the Number of Treatable Warts (Baseline and New) at the EOT Visit (Day 84).
Baseline (Visit 1) to End of Treatment Visit (Day 84).
Cohort 1: Proportion of Subjects Exhibiting Complete Clearance of All Treatable Warts (Baseline and New) at Visit 2, Visit 3, Visit 4 and Over the Duration of the Study
Baseline, Day 14, 28, 42 and 84 (EOS)
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSEQUENTIAL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
VP-102EXPERIMENTALOpen label of VP-102 cantharidin topical film forming solution, using the VP-102 applicator.

Interventions

NameTypeDescription
VP-102 Cantharidin topical film forming solutionCOMBINATION_PRODUCTVP-102, a single-use drug device combination product containing (cantharidin) topical solution, 0.7% (w/v). Treatment interval of at least 14 days between treatments.
VP-102 Cantharidin, topical film forming solutionCOMBINATION_PRODUCTVP-102, a single-use drug device combination product containing (cantharidin) topical solution, 0.7% (w/v). Treatment interval of at least 21 days between treatments.
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Eligibility Criteria

Age Range2 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites5

Inclusion Criteria: 1. Be healthy, immunocompetent males or females at least 2 years of age and older for Cohort 1 and 12 years of age and older for Cohort 2. 2. Present with 1-6 common warts (verruca vulgaris) located anywhere on the body except for the following prohibited areas: the eye area (in...

Countries:United States
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Frequently asked questions about VP-102 Cantharidin film forming

What is VP-102 Cantharidin film forming used for?

VP-102 Cantharidin film forming is an investigational small molecule therapy being studied for the treatment of common warts, including warts on the hands and verruca vulgaris. It is applied as a topical film forming solution. The drug is in Phase 2 clinical development and has not been approved by the FDA.

Who makes VP-102 Cantharidin film forming?

VP-102 Cantharidin film forming is being developed by Verrica Pharmaceuticals Inc., which trades on the Nasdaq under the ticker symbol VRCA. Verrica is the sponsor of the clinical program evaluating this topical cantharidin formulation for common warts.

What phase is VP-102 Cantharidin film forming in?

VP-102 Cantharidin film forming is in Phase 2 clinical development. One Phase 2 trial has been completed, and there are currently no active trials listed for this asset. The drug remains investigational and has not received FDA approval for any indication.

What clinical trials is VP-102 Cantharidin film forming in?

VP-102 Cantharidin film forming has been evaluated in one completed Phase 2 trial, NCT03487549, titled Cantharidin and Occlusion in Verruca Epithelium. The trial enrolled 56 participants in the United States and studied common warts, hand warts, and verruca vulgaris. It was an uncontrolled study without randomization or double blinding.

Is VP-102 Cantharidin film forming the same as VP-102 Cantharidin topical film forming solution?

Yes, VP-102 Cantharidin film forming is also known as VP-102 Cantharidin topical film forming solution. Both names refer to the same investigational topical product developed by Verrica Pharmaceuticals for common warts.