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VP-102 Cantharidin film forming

Phase 2

Common Wart | Small molecule | Oncology |Verrica Pharmaceuticals Inc.|Last Updated: Nov 27, 2024

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment56

FDA Designations

No designations recorded

Clinical trial landscape

VP-102 Cantharidin film forming · 1 trial · 12 indications

Phase 2 1
NCT03487549Cantharidin and Occlusion in Verruca EpitheliumCommon Wart
COMPLETED56 Analytics
PHASE2COMPLETED
Cantharidin and Occlusion in Verruca Epithelium
Common WartUnlock trial analytics

Study Endpoints

Primary Endpoints

Cohort 1: Proportion of Subjects Exhibiting Complete Clearance of All Treatable Warts (Baseline and New) at the EOS Visit (Day 84)
Treatment Visit Day 1 (Baseline) compared to Day 84 (EOS) Visit.

Cohort 1: Proportion of subjects exhibiting complete clearance of all treatable warts (baseline and new) at the EOS Visit (Day 84).

Cohort 2: Proportion of Subjects Exhibiting Complete Clearance of All Treatable Warts (Baseline and New) at the EOT Visit (Day 84)
Compare Treatment Visit 1 (Baseline) to EOT Visit (Day 84)

Cohort 2: Proportion of subjects exhibiting complete clearance of all treatable warts (baseline and new) at the EOT Visit (Day 84).

Secondary Endpoints

Cohort 1: Change From Baseline in the Number of Treatable Warts (Baseline and New) at the EOS Visit (Day 84)
Change in the number of warts compared at Baseline (Visit 1) to the End of Study Visit (Day 84).
Cohort 1: Percent Change From Baseline in the Number of Treatable Warts (Baseline and New) at the EOT Visit (Day 84).
Baseline (Visit 1) to End of Treatment Visit (Day 84).
Cohort 1: Proportion of Subjects Exhibiting Complete Clearance of All Treatable Warts (Baseline and New) at Visit 2, Visit 3, Visit 4 and Over the Duration of the Study
Baseline, Day 14, 28, 42 and 84 (EOS)
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSEQUENTIAL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
VP-102EXPERIMENTALOpen label of VP-102 cantharidin topical film forming solution, using the VP-102 applicator.

Interventions

NameTypeDescription
VP-102 Cantharidin topical film forming solutionCOMBINATION_PRODUCTVP-102, a single-use drug device combination product containing (cantharidin) topical solution, 0.7% (w/v). Treatment interval of at least 14 days between treatments.
VP-102 Cantharidin, topical film forming solutionCOMBINATION_PRODUCTVP-102, a single-use drug device combination product containing (cantharidin) topical solution, 0.7% (w/v). Treatment interval of at least 21 days between treatments.
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Eligibility Criteria

Age Range2 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites5

Inclusion Criteria: 1. Be healthy, immunocompetent males or females at least 2 years of age and older for Cohort 1 and 12 years of age and older for Cohort 2. 2. Present with 1-6 common warts (verruca vulgaris) located anywhere on the body except for the following prohibited areas: the eye area (in...

Countries:United States
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Frequently asked questions about VP-102 Cantharidin film forming

What is VP-102 Cantharidin film forming used for?

VP-102 Cantharidin film forming is an investigational small molecule being developed for the treatment of common warts, also known as verruca vulgaris. It is a topical film-forming formulation of cantharidin, a substance derived from blister beetles, that is applied directly to the wart. The drug is currently in Phase 2 clinical development.

Who makes VP-102 Cantharidin film forming?

VP-102 Cantharidin film forming is being developed by Verrica Pharmaceuticals Inc., a biopharmaceutical company traded on the NASDAQ under the ticker symbol VRCA. The company is conducting clinical trials to evaluate the safety and efficacy of this investigational drug for the treatment of common warts.

What phase is VP-102 Cantharidin film forming in?

VP-102 Cantharidin film forming is in Phase 2 clinical development. It is an investigational drug and has not been approved by the FDA. The drug is being studied for the treatment of common warts, and a Phase 2 clinical trial has been completed to evaluate its effects.

What clinical trials is VP-102 Cantharidin film forming in?

VP-102 Cantharidin film forming has been studied in one clinical trial with the identifier NCT03487549, titled 'Cantharidin and Occlusion in Verruca Epithelium.' This Phase 2 trial enrolled 56 participants with common warts and was completed in the United States. The trial was uncontrolled and did not use randomization or blinding.

Is VP-102 Cantharidin film forming the same as cantharidin?

VP-102 Cantharidin film forming is a specific formulation of cantharidin, a chemical compound derived from blister beetles. The drug is designed as a film-forming topical solution that delivers cantharidin to the skin. It is being developed by Verrica Pharmaceuticals for the treatment of common warts.