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Tamsulosin- 1 week

Phase 1

Urinary Retention | Small molecule | Nephrology |Meridian Bioscience Inc|Last Updated: Jun 11, 2026

Target and mechanism

ModalitySmall molecule

Also known as Tamsulosin - 1 week

Success Probability

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Market & Valuation

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Trial Design

CONTROLLEDBiomarker
Total Trials1
Total Enrollment127

FDA Designations

No designations recorded

Clinical trial landscape

Tamsulosin- 1 week · 1 trial · 1 indication

Phase 1 1
NCT03609580Post-operative Urinary Retention (POUR) Following Thoracic SurgeryUrinary Retention
RECRUITING127 Analytics
PHASE1RECRUITING
Post-operative Urinary Retention (POUR) Following Thoracic Surgery
Urinary RetentionUnlock trial analytics

Study Endpoints

Primary Endpoints

Volume of urine (cc) post thoracic surgery in patients that received Flomax, 0.4mg/day for a week before surgery
8 hours

The absence of voiding naturally after undergoing thoracic surgery needing an intervention as a Foley catheter or a catheterization. Documentation for first void, Post bladder scan showing more that 300cc of residual urine in the bladder (failure to urinate), or following spontaneous urination if there is more than 300cc of residual urine in the bladder (inadequate urination)

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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1 week Pre-operative Tamsulosin administrationEXPERIMENTAL -
3 days Pre-operative Tamsulosin administrationEXPERIMENTAL -

Interventions

NameTypeDescription
Tamsulosin - 1 weekDRUGThe investigators hypothesize that pre-operative administration of Tamusolin (Flomax, 0.4mg/day x 1 week), with ongoing use post-operatively until normal voiding resumes, will result in a significant decrease in the incidence of POUR after a thoracic surgical procedure.
Tamsulosin - 3 daysDRUGThe investigators hypothesize that pre-operative administration of Tamusolin (Flomax, 0.4mg/day x 3 days), with ongoing use post-operatively until normal voiding resumes, will result in a significant decrease in the incidence of POUR after a thoracic surgical procedure.
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Eligibility Criteria

Age Range50 Years to N/A
SexMALE
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: Males ≥50 years old Planned surgical procedure of a minimally invasive thoracic surgical procedure (wedge resection, segmentectomy, lobectomy, pleural biopsy, or pleurodesis) Surgery scheduled more than 3 days from the time of consent Exclusion Criteria: * Using Flomax alread...

Countries:United States
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Frequently asked questions about Tamsulosin- 1 week

What is Tamsulosin - 1 week used for?

Tamsulosin - 1 week is an investigational small molecule being studied for the treatment of urinary retention, specifically post-operative urinary retention following thoracic surgery. It is currently in Phase 1 clinical development and has not been approved by the FDA.

Who makes Tamsulosin - 1 week?

Tamsulosin - 1 week is being developed by Meridian Bioscience Inc, which trades under the ticker VIVO. The company is conducting a Phase 1 clinical trial to evaluate the drug for urinary retention.

What phase is Tamsulosin - 1 week in?

Tamsulosin - 1 week is in Phase 1 clinical development. It is an investigational drug and has not yet been approved by the FDA. The ongoing trial is recruiting participants to study its effects on post-operative urinary retention.

What clinical trials is Tamsulosin - 1 week in?

Tamsulosin - 1 week is being studied in a single Phase 1 clinical trial with the identifier NCT03609580. The trial, titled 'Post-operative Urinary Retention (POUR) Following Thoracic Surgery,' is recruiting 127 male participants aged 50 years and older in the United States.

Is Tamsulosin - 1 week the same as Tamsulosin - 1 week?

Yes, Tamsulosin - 1 week is also known as Tamsulosin - 1 week. The drug is being developed by Meridian Bioscience Inc for the treatment of urinary retention and is currently in Phase 1 clinical trials.