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Dual Mode BreathID Hp System

Phase 3

Helicobacter Pylori Infection | Unknown | Infectious Disease |Meridian Bioscience Inc|Last Updated: Dec 20, 2022

Success Probability

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Trial Design

CONTROLLED
Total Trials1
Total Enrollment282

FDA Designations

No designations recorded

Clinical trial landscape

Dual Mode BreathID Hp System · 1 trial · 1 indication

Phase 3 1
NCT02528721Exalenz Lab Mode System Compared to Biopsy for H.Pylori DetectionHelicobacter Pylori Infection
COMPLETED282 Analytics
PHASE3COMPLETED
Exalenz Lab Mode System Compared to Biopsy for H.Pylori Detection
Helicobacter Pylori InfectionUnlock trial analytics

Study Endpoints

Primary Endpoints

Sensitivity is Described as the Accuracy of the Breath Test in Detecting H.Pylori Infection Compared to Biopsy
9 months

Sensitivity of urea breath test with Dual Mode Breath Hp System in accurately detecting presence of H.pylori infection as compared to composite biopsy result

Specificity as Described as the Accuracy of the Breath Test in Detecting Absence of H.Pylori Infection Compared to Biopsy
9 months

Specificity of urea breath test with Dual Mode Breath Hp System in accurately detecting lack of presence of H.pylori infection as compared to composite biopsy result

Overall Agreement in Determining Presence or Absence of H.Pylori Infection Compared to Biopsy
9 months

Overall Agreement of urea breath test with Dual Mode Breath Hp System in accurately detecting presence of H.pylori infection as compared to composite biopsy result

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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingSINGLE
ModelPARALLEL
PurposeDIAGNOSTIC

Treatment Arms

ArmTypeDescription
Initial Diagnosis SubjectsEXPERIMENTALPatients with clinical indication for H.pylori infection
Post Therapy SubjectsEXPERIMENTALPatients wishing to confirm eradication of initially diagnosed H.pylori infection that are after treatment within the last 6 months

Interventions

NameTypeDescription
Dual Mode BreathID Hp SystemDEVICEThe Dual Mode Breath ID Hp System consists of breath collection bags, a 13C-labelled substrate (urea) and a breath analyzer device
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites13

Inclusion Criteria: * Be at least 18 years of age. * Have the ability and willingness to sign the Informed Consent Form. * Present with clinical indication of H. pylori and a candidate for upper endoscopy For Initial Diagnosis arm: • Symptomatic patients naïve to H.pylori treatment in the past 18...

Countries:United StatesIsrael
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Frequently asked questions about Dual Mode BreathID Hp System

What is the Dual Mode BreathID Hp System used for?

The Dual Mode BreathID Hp System is used for the detection of Helicobacter pylori infection. It is an investigational diagnostic device being evaluated in a Phase 3 clinical trial for this infectious disease indication.

Who makes the Dual Mode BreathID Hp System?

The Dual Mode BreathID Hp System is being developed by Meridian Bioscience Inc, which trades under the ticker VIVO. The company is conducting clinical research to evaluate this diagnostic system for Helicobacter pylori detection.

What phase is the Dual Mode BreathID Hp System in?

The Dual Mode BreathID Hp System is in Phase 3 clinical development. It is an investigational diagnostic device and has not been approved for use. One Phase 3 trial for this system has been completed.

What clinical trials is the Dual Mode BreathID Hp System in?

The Dual Mode BreathID Hp System has one completed Phase 3 clinical trial, NCT02528721, titled 'Exalenz Lab Mode System Compared to Biopsy for H.Pylori Detection'. This trial enrolled 282 participants in the United States and Israel.

Is the Dual Mode BreathID Hp System the same as the Exalenz Lab Mode System?

The Dual Mode BreathID Hp System is evaluated in a clinical trial that compares it to biopsy for H. pylori detection. The trial title references the 'Exalenz Lab Mode System', which may be an alternative name for this diagnostic system.