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Breath Test Collection bags

Phase 3

Helicobacter Pylori Infection | Unknown | Other |Meridian Bioscience Inc|Last Updated: Dec 20, 2022

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment193
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT02010112Bag Mode BreathID Hp Validation Versus Endoscopy in Detection of Helicobacter PyloriPHASE3 COMPLETED 193Jan 1, 2014Feb 1, 2015Dec 20, 20229 United States
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Study Endpoints
Primary Endpoints
overall percent agreement
21 days

The primary study endpoint is the performance measure (overall percent agreement) in initial diagnosis (presence/ absence of H.pylori) between biopsy results and bag mode breath test.

Secondary Endpoints
overall percent agreement
21 days
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Study Design & Arms
AllocationNA
MaskingSINGLE
ModelSINGLE_GROUP
PurposeDIAGNOSTIC
Treatment Arms
ArmTypeDescription
Initial Diagnosis CohortEXPERIMENTALSubjects with clinical indication of H.pylori infection will undergo breath test compared to routine clinical standard of care- endoscopy
Interventions
NameTypeDescription
Breath Test Collection bagsOTHERBreath Collection bags will be used to collect breath of subjects before and after ingestion of 13-C breath test substrate
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites9

Inclusion Criteria: * Present with clinical indication of H. pylori and candidate for upper endoscopy * Have the ability and willingness to sign the Informed Consent Form for initial diagnosis cohort * Naive to treatment in the past 18 months * No known H.pylori status (no conclusive test results w...

Countries:United States
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