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Twist Bioscience Corporation

TWSTFDA catalysts, PDUFA dates & pipeline intelligence
$142.95
▲ +2.88 · +2.06%

Financials

Last updated
Revenue
R&D Expenses
Operating CF
Total Assets
Total Liabilities
Equity
Shares Out.
D/E Ratio
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Quarterly Cash
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52W LOW $23.3052W HIGH $219.71
Volume
242.75 K
Value Traded
325.98 M
Short % Float
16.51%
Days to Cover
3.8
-1.55%Week
-23.38%1 Month
+59.01%3 Month
+125.59%6 Month
-38.59%5 Year
+365.92%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
  • Dilution Risk
  • SEC Filing

Key Stats

Market Cap
8.94 B
EPS (TTM)
-2.06
P/E Ratio
-
Ent. Value
8.51 B
Total Shares
62.71 M
Float Shares
64.01 M
Insiders
2.77%
Institutions
121.38%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
PDUFA
2026
Example Drug
Treatment for example condition requiring FDA review
Phase 3Small MoleculeOncology-
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

TWST Catalyst Timeline

Dated clinical, regulatory and corporate events for Twist Bioscience Corporation

Catalyst Timeline

Dated clinical, regulatory & corporate events for Twist Bioscience Corporation

100Total events
2Upcoming
16Tier-1 (high impact)
2022 to 2026Coverage

Upcoming catalysts 2

T2Timing Guidance
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TBD
T2Equity Offering
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Event history 50

▲Partnership / LicenseCorporate
Twist Bioscience joins Lilly TuneLab AI/ML drug discovery platform as antibody characterization data provider
◆Equity OfferingCorporate
Expected closing of the public offering
▼Equity OfferingCorporate
Pricing of upsized $300.0 million public offering of 3,125,000 shares of common stock at $96.00 per share
▼Equity OfferingCorporate
Twist Bioscience commences $250.0M underwritten public offering of common stock
●Quarterly UpdateCorporate
Twist Bioscience reports fiscal 2026 third quarter financial results
●R&D DayPresentation
Conference call and webcast to discuss financial results
◆Oral PresentationPresentation
Twist Bioscience presentation at William Blair 46th Annual Growth Stock Conference
●Quarterly UpdateCorporate
Q3 FY2026 revenue guidance of ~$114-115M
◆R&D DayPresentation
Investor Day with facility tour and management presentations
◆Quarterly UpdateCorporate
Fiscal 2026 Second Quarter Financial Results
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How TWST actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
-Example Drug Phase 3 data readout Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

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Every scored asset with PTRS, rNPV, enrollment velocity and trial design quality.
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Clinical Trial Results

Readouts, endpoints and source filings for every TWST program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
Example Drug Example indication for clinical evaluationPhase 32025-12-01The study met its primary endpoint demonstrating statistically significant improvement.Read MorePhase 3 Study Results AnnouncementRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Laponis AdamOfficer (Chief Financial Officer)Sell -2,462 98,114 held$156.30 10/09/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
SOLEUS CAPITAL MANAGEMENT, L.P. 0.4 % (-83.3 %) 10.76 M 104.63 K -91.47% ( -1.12 M)
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

TWST Institutional Ownership Trends

TWST Short Interest

Shares sold short, counted twice a month.

16.51%
Short % of Float
of tradable shares sold short
10.6M
Shares Sold Short
-15.5% vs prior count
3.8 Moderate
Days to Cover
trading days of normal volume to buy every short share back
2.8M
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-11-20
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Live calls and puts by strike: last price, volume and open interest for every expiry.
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How TWST ranks across every disease it competes in

Competitive Position is a premium feature
See how TWST ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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TWST News

TWST
Oct 26, 2026
TWSTConferences/Events
▲ +2.1%today

Twist Bioscience to Report Fiscal 2026 Fourth Quarter and Full Year Financial Results on Thursday, November 12, 2026

Twist Bioscience Corporation will release its fiscal 2026 fourth quarter and full year financial results on November 12, 2026. The results will cover the period ending September 30, 2026. A conference call is scheduled for 8:00 a.m. Eastern Time to discuss the results and provide updates.

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TWST
Sep 16, 2026
TWSTGeneral

Twist Bioscience Joins Lilly TuneLab to Advance Antibody Drug Discovery

Twist Bioscience Corporation has entered into a partnership with Lilly TuneLab, an AI/ML drug discovery platform developed by Eli Lilly. This collaboration will allow Twist to provide antibody characterization data services, including the AbLab model, to enhance the drug discovery process. The partnership aims to foster innovation in the biotech sector.

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TWST
Sep 9, 2026
TWSTConferences/Events

Twist Bioscience to Present at Baird 2026 Global Healthcare Conference

Twist Bioscience Corporation announced that its CEO, Dr. Emily M. Leproust, and CFO, Adam Laponis, will participate in a fireside chat at the Baird 2026 Global Healthcare Conference. The event is scheduled for September 15, 2026, and will be webcast live, allowing broader access to the discussion.

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TWST
Aug 5, 2026
TWSTGeneral
▲ +15.7%on this news

Twist Bioscience Announces Pricing of Upsized $300.0 Million Public Offering of Common Stock

Twist Bioscience Corporation has announced the pricing of an upsized public offering of 3,125,000 shares of common stock at $96.00 per share. The offering aims to raise $300 million in gross proceeds, which will be used for corporate purposes. All shares will be sold by Twist, indicating a strong demand for its stock.

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TWST
Aug 4, 2026
TWSTGeneral
▲ +15.7%on this newsshared move

Twist Bioscience Announces Proposed Public Offering of $250.0 Million of Common Stock

Twist Bioscience Corporation has announced a proposed public offering of $250 million in common stock. The company also plans to grant underwriters a 30-day option to purchase an additional $37.5 million in shares. This move aims to bolster its financial resources and support future growth initiatives.

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TWST
Aug 4, 2026
TWSTGeneral

Twist Bioscience Corporation Announces Inducement Grants under NASDAQ Listing Rule 5635(c)(4)

Twist Bioscience Corporation has announced the granting of 44,434 restricted stock units (RSUs) to 24 new employees as an inducement for their acceptance of employment. This move aligns with Nasdaq Listing Rule 5635(c)(4), demonstrating the company's commitment to attracting skilled professionals. The RSUs are part of the company's strategy to enhance its workforce.

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TWST
Aug 3, 2026
TWSTGeneral
▲ +10.4%on this newsshared move

Twist Bioscience Announces Fiscal 2026 Third Quarter Financial Results

Twist Bioscience Corporation announced its financial results for the third quarter of fiscal 2026, which ended on June 30, 2026. The company highlighted its growth and value in the biotech industry. Investors can access detailed reports and presentations through their website.

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TWST
Jul 15, 2026
TWSTGeneral

Twist Bioscience to Report Fiscal 2026 Third Quarter Financial Results on Monday, August 3, 2026

Twist Bioscience Corporation will release its financial results for the fiscal 2026 third quarter on August 3, 2026. The results will cover the period ending June 30, 2026, and will be announced before the market opens. Following the announcement, the company will host a conference call and live audio webcast to discuss the results and provide a business update.

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TWST
May 27, 2026
TWSTConferences/Events

Twist Bioscience to Present at William Blair 46th Annual Growth Stock Conference

Twist Bioscience is scheduled to present at the William Blair 46th Annual Growth Stock Conference. Details regarding the presentation content or specific topics have not been disclosed in the article.

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TWST
May 4, 2026
TWSTGeneral
▼ -7%on this news

Twist Bioscience Expands Clonal Genes Offering to Include Long and Complex Sequences

Twist Bioscience has expanded its clonal genes offering to include long and complex sequences. This move aims to enhance their product portfolio and cater to a broader range of applications in synthetic biology. The expansion reflects the company's commitment to innovation and meeting customer needs in the biopharma sector.

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TWST
May 4, 2026
TWSTGeneral
▼ -7%on this news

Twist Bioscience Reports Fiscal Second Quarter 2026 Financial Results

Twist Bioscience Corporation reported its fiscal second quarter 2026 financial results, showcasing a record revenue of $110.7 million, reflecting a 19% increase compared to the same quarter last year. This quarter marks the thirteenth consecutive quarter of growth for the company, with improved gross margins. Despite the positive financial results, the company reported a net loss of $44.0 million and an increase in selling, general and administrative expenses. Looking forward, Twist has raised its revenue guidance for fiscal 2026 and anticipates achieving adjusted EBITDA breakeven by the fourth quarter.

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TWST
May 4, 2026
TWSTGeneral
▼ -7%on this news

Twist Bioscience Announces Fiscal 2026 Second Quarter Financial Results

Twist Bioscience has announced its financial results for the second quarter of fiscal 2026. The report includes key financial metrics and performance indicators, although specific details on revenue or growth were not disclosed in the provided text. The announcement is part of the company's ongoing financial reporting.

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TWST
Apr 21, 2026
TWSTConferences/Events

Twist Bioscience to Report Fiscal 2026 Second Quarter Financial Results on Monday, May 4, 2026

Twist Bioscience Corporation will announce its fiscal 2026 second quarter financial results on May 4, 2026, before market opening. A conference call will follow at 8:00 a.m. ET for discussion and updates. Additionally, an Investor Day is scheduled for May 21, 2026, featuring a facility tour and presentations from senior leaders.

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TWST
Feb 18, 2026
TWSTConferences/Events

Twist Bioscience to Present at Upcoming Investor Conferences

Twist Bioscience Corporation announced that its CEO, Dr. Emily M. Leproust, and CFO, Adam Laponis, will participate in upcoming investor conferences through fireside chats. These events will be webcast live and available for replay for 30 days. The company emphasizes its role in supporting customers across various industries with its advanced DNA synthesis technology.

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TWST
Feb 17, 2026
TWSTGeneral
▲ +7.7%on this newsshared move

Twist Bioscience Expands Antibody Discovery Offering with Bispecific Licensing Agreement

Twist Bioscience has entered a licensing agreement with Invenra to co-exclusively provide the B-Body bispecific antibody platform. This partnership aims to enhance Twist's antibody discovery services and meet the increasing demand for bispecific therapeutics. The deal includes a $5 million upfront payment and a 6% ownership stake in Invenra. Twist's CEO emphasizes the potential of bispecific antibodies in addressing unmet medical needs.

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TWST
Feb 10, 2026
TWSTGeneral

Twist Bioscience Launches Next-Generation Library Preparation Kits Powered by Proprietary Enzymes

Twist Bioscience has launched two next-generation library preparation kits, the Twist TrueAmp and the Twist PCR-Free WGS Library Preparation Kits. These kits are designed to enhance sequencing accuracy and efficiency, particularly for low-input and difficult sample types. The TrueAmp polymerase and engineered ligase improve performance and reduce errors, catering to various clinical research applications.

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TWST
Feb 4, 2026
TWSTGeneral

Twist Bioscience Corporation Announces Inducement Grants under NASDAQ Listing Rule 5635(c)(4) - February 3, 2026

Twist Bioscience Corporation announced the grant of 114,869 equity awards to 52 new employees as an inducement for joining the company. This includes 107,742 restricted stock units (RSUs) and up to 7,127 performance stock units (PSUs). The awards are structured to vest over a 48-month period, contingent on continued employment and performance metrics.

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TWST
Feb 2, 2026
TWSTGeneral
▲ +14%on this news

Twist Bioscience Announces Fiscal 2026 First Quarter Financial Results

Twist Bioscience Corporation announced its financial results for the first quarter of fiscal 2026, ending December 31, 2025. The company highlighted its innovative DNA synthesis platform, which supports advancements in medicine, agriculture, and other sectors. A conference call is scheduled to discuss these results and company updates.

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TWST
Feb 2, 2026
TWSTGeneral
▲ +14%on this newsshared move

Twist Bioscience Reports Fiscal First Quarter 2026 Financial Results

Twist Bioscience reported financial results for the first quarter of fiscal 2026, showcasing record revenue of $103.7 million, a 17% increase from the same quarter last year. The company achieved a gross margin of 52.0%, marking an improvement over the previous year, and raised its full-year revenue guidance to between $435 million and $440 million. Despite these positives, the company posted a net loss of $30.5 million and continued to operate at a loss in adjusted EBITDA, though this figure improved from the prior year’s loss. Twist remains focused on maintaining revenue growth while aiming for profitability.

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About Twist Bioscience Corporation

South San Francisco, CA 979 employees twistbioscience.com
Headquarters681 GATEWAY BLVD., SOUTH SAN FRANCISCO, CA, 94080
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