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Third Harmonic Bio, Inc.

THRDFDA catalysts, PDUFA dates & pipeline intelligence
$5.38
▼ -0.03 · -0.55%

Last traded Jul 30, 2025. This price is not current.

Financials

Last updated
Revenue
R&D Expenses
Operating CF
Total Assets
Total Liabilities
Equity
Shares Out.
D/E Ratio
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Quarterly Cash
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52W LOW $3.1852W HIGH $16.02
Volume
1.42 M
Value Traded
7.61 M
Short % Float
6.4%
Days to Cover
9.5
-1.28%Week
-0.92%1 Month
+4.06%3 Month
0%6 Month
-73.76%5 Year
-73.76%All Time

Cash Data

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  • Monthly Burn
  • Burn Trend
  • Dilution Risk
  • SEC Filing

Key Stats

Market Cap
242.79 M
EPS (TTM)
-1.24
P/E Ratio
-
Ent. Value
-25.82 M
Total Shares
45.13 M
Float Shares
22.29 M
Insiders
50.60%
Institutions
39.45%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

THRD Catalyst Timeline

Dated clinical, regulatory and corporate events for Third Harmonic Bio, Inc.

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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How THRD actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2025-03-02THB335 (oral small molecule inhibitor of KIT) Phase 1 data readout Phase 1
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Valuation Signal
1
Drugs Scored
rNPV / MCap
Top Drug
Showing 1 of 1 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
THB335 single dose Small moleculeCompletedNCT06425861UndisclosedPhase 1 COMPLETED 60Dec 18, 2024
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PTRS, rNPV, enrollment velocity, trial design quality and ML risk signals for every asset above.
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Clinical Trial Results

Readouts, endpoints and source filings for every THRD program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
THB335 chronic spontaneous urticariaPhase 12025-02-11SAD: n 48, dose levels 21, 41, 82, 164, 205, half life approximately 40 hours, exposure trough plasma exposures exceeding the KIT IC90 at MAD dose levels of 41 mg QD and greater; MAD: n 32, dose levels 21, 41, 82, 205, mean reductions from baseline min 13, max 84Read MoreThird Harmonic Bio Announces Phase 1 Clinical Results for THB335 and Provides Corporate Strategic UpdateRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Conner Edward R.Officer (Chief Medical Officer)Option 2,117 2,117 held$4.20 11/08/2024
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Hedge Fund 13F Activity

Hedge Funds invested in THRD

Fund % of Portfolio Current MV Shares Owned Activity
ORBIMED ADVISORS LLC 0.8 % (60 %) 31.38 M 5.78 M
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

Ownership Trends

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Insider and institutional ownership, quarter by quarter.

THRD Short Interest

Shares sold short, counted twice a month.

6.4%
Short % of Float
of tradable shares sold short
1.4M
Shares Sold Short
-4.0% vs prior count
9.5 High
Days to Cover
trading days of normal volume to buy every short share back
150.0K
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Live calls and puts by strike: last price, volume and open interest for every expiry.
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How THRD ranks across every disease it competes in

Competitive Position is a premium feature
See how THRD ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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THRD News

About Third Harmonic Bio, Inc.

Founded14-09-2022
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