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TEV-56286 Dose A

Phase 1

Healthy Volunteers | Small molecule | Other |Teva Pharmaceutical Industries Limited|Last Updated: Jul 2, 2026

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindCONTROLLEDBiomarker
Total Trials1
Total Enrollment60

FDA Designations

No designations recorded

Clinical trial landscape

TEV-56286 Dose A · 1 trial · 1 indication

Phase 1 1
NCT07674940A Trial to Assess TEV-56286 at Different Doses in Healthy ParticipantsHealthy Volunteers
NOT YET_RECRUITING60 Analytics
PHASE1NOT YET_RECRUITING
A Trial to Assess TEV-56286 at Different Doses in Healthy Participants
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Study Endpoints

Primary Endpoints

SAD: Time to maximum observed plasma drug concentration (tmax) of TEV-56286
Day 1 to Day 3
SAD: Maximum observed plasma concentration (Cmax) of TEV-56286
Day 1 to Day 3
SAD: Area Under the Plasma Drug Concentration-Time Curve from Time 0 to the Time of the Last Measurable Concentration (AUC0-t) of TEV-56286
Day 1 to Day 3
SAD: Area Under the Plasma Drug Concentration-Time Curve from Time 0 to Infinity (AUC0-inf) of TEV-56286
Day 1 to Day 3
MD: tmax of TEV-56286
Day 7 to Day 9
MD: Cmax of TEV-56286
Day 7 to Day 9
MD: AUC0-t of TEV-56286
Day 7 to Day 9
MD: Area Under the Plasma Drug Concentration-Time Curve for the Defined Interval Between Doses (AUC0-tau) of TEV-56286
Day 7 to Day 8

Secondary Endpoints

Number of participants with at least 1 treatment-emergent adverse event
Up to Day 17
Number of participants who did not complete the trial due to an adverse event
Up to Day 17
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelSEQUENTIAL
PurposeOTHER

Treatment Arms

ArmTypeDescription
Group 1: Single Ascending Dose (SAD1)EXPERIMENTAL -
Group 2: Single Ascending Dose (SAD2)EXPERIMENTAL -
Group 3: Single Ascending Dose (SAD3)EXPERIMENTAL -
Group 4: Single Ascending Dose (SAD4)EXPERIMENTAL -
Group 5: Multiple Dose (MD1)EXPERIMENTAL -

Interventions

NameTypeDescription
TEV-56286 Dose ADRUGoral administration
TEV-56286 Dose BDRUGoral administration
TEV-56286 Dose CDRUGoral administration
TEV-56286 Dose DDRUGoral administration
TEV-56286 Dose EDRUGoral administration
PlaceboDRUGmatching placebo
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Eligibility Criteria

Age Range18 Years to 60 Years
SexALL
Healthy VolunteersYes

Inclusion Criteria: * Participant is a healthy male or female with a body weight of ≥50 kg for males and ≥45 kg for females, and body mass index (BMI) of 18.5 to 32.0 kg/m2 inclusive. * Participant is 18 to 60 years of age inclusive, at the time of signing the informed consent form (ICF). * Female ...

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Frequently asked questions about TEV-56286 Dose A

What is TEV-56286 Dose A used for?

TEV-56286 Dose A is an investigational small molecule being studied in healthy volunteers. It is currently in Phase 1 clinical development, with a trial assessing different doses in healthy participants. The drug is not approved and is still in early-stage clinical testing.

Who makes TEV-56286 Dose A?

TEV-56286 Dose A is being developed by Teva Pharmaceutical Industries Limited, a company traded on the New York Stock Exchange under the ticker TEVA. The drug is currently in Phase 1 clinical development.

What phase is TEV-56286 Dose A in?

TEV-56286 Dose A is in Phase 1 clinical development. It is an investigational drug being studied in a trial of healthy volunteers, and it has not been approved by regulatory authorities.

What clinical trials is TEV-56286 Dose A in?

TEV-56286 Dose A is being evaluated in a Phase 1 trial with the identifier NCT07674940, titled 'A Trial to Assess TEV-56286 at Different Doses in Healthy Participants.' The trial is not yet recruiting and plans to enroll 60 participants.

Is TEV-56286 Dose A the same as TEV-56286?

TEV-56286 Dose A is a specific dose level of the investigational drug TEV-56286. The Phase 1 trial NCT07674940 is designed to assess TEV-56286 at different doses, with Dose A being one of the dose levels being studied.